product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
TAZ
catalog :
560235
quantity :
0.1 mg
price :
278.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M2-616
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, other
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4d
Park B, Chang S, Lee G, Kang B, Kim J, Park H. Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis. Cell Death Dis. 2019;10:16 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1a
Lu L, Finegold M, Johnson R. Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration. Exp Mol Med. 2018;50:e423 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 2d
  • western blot; human; loading ...; fig 2g
Heidary Arash E, Shiban A, Song S, Attisano L. MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells. EMBO Rep. 2017;18:420-436 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 3a
  • western blot; human
Lee H, Diaz M, Price K, Ozuna J, Zhang S, Sevick Muraca E, et al. Fluid shear stress activates YAP1 to promote cancer cell motility. Nat Commun. 2017;8:14122 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
  • immunoprecipitation; human; loading ...; fig s3d
  • western blot; human; loading ...; fig s1e
Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed publisher
  • immunocytochemistry; mouse; fig 3b
  • western blot; mouse; fig 4i
  • immunoprecipitation; human; loading ...; fig 2b
  • immunocytochemistry; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 2b
Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
  • western blot; human; loading ...; fig 4f
Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 6
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed publisher
  • western blot; human; fig 3
Liu X, Li H, Rajurkar M, Li Q, Cotton J, Ou J, et al. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016;14:1169-1180 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 1c
Finch Edmondson M, Strauss R, Passman A, Sudol M, Yeoh G, Callus B. TAZ Protein Accumulation Is Negatively Regulated by YAP Abundance in Mammalian Cells. J Biol Chem. 2015;290:27928-38 pubmed publisher
  • immunocytochemistry; human; fig 1
Hwang J, Byun M, Kim A, Kim K, Cho H, Lee Y, et al. Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation. PLoS ONE. 2015;10:e0135519 pubmed publisher
  • other; human; 1:200; loading ...; fig 2c
  • western blot; human; loading ...; fig 2
Wang M, Liu Y, Zou J, Yang R, Xuan F, Wang Y, et al. Transcriptional co-activator TAZ sustains proliferation and tumorigenicity of neuroblastoma by targeting CTGF and PDGF-β. Oncotarget. 2015;6:9517-30 pubmed
  • immunocytochemistry; human; 1:100; fig 1
Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the ?-catenin destruction complex orchestrates the Wnt response. Cell. 2014;158:157-70 pubmed publisher
  • immunocytochemistry; mouse
Martianov I, Cler E, Duluc I, Vicaire S, Philipps M, Freund J, et al. TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3. PLoS ONE. 2014;9:e87365 pubmed publisher
  • immunocytochemistry; human; 1:200; fig s1
Nallet Staub F, Marsaud V, Li L, Gilbert C, Dodier S, Bataille V, et al. Pro-invasive activity of the Hippo pathway effectors YAP and TAZ in cutaneous melanoma. J Invest Dermatol. 2014;134:123-132 pubmed publisher
Hoj J, Mayro B, Pendergast A. A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis. Cell Rep. 2019;29:3421-3434.e8 pubmed publisher
Yang W, Ding C, Sun T, Rupprecht G, Lin C, Hsu D, et al. The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma. Cell Rep. 2019;28:2501-2508.e4 pubmed publisher
Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, et al. OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ. Mol Cell. 2019;73:7-21.e7 pubmed publisher
Gill M, Christova T, Zhang Y, Gregorieff A, Zhang L, Narimatsu M, et al. A feed forward loop enforces YAP/TAZ signaling during tumorigenesis. Nat Commun. 2018;9:3510 pubmed publisher
Astone M, Lai J, Dupont S, Stainier D, Argenton F, Vettori A. Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Sci Rep. 2018;8:10189 pubmed publisher
Melucci E, Casini B, Ronchetti L, Pizzuti L, Sperati F, Pallocca M, et al. Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy. J Transl Med. 2018;16:22 pubmed publisher
Lee H, Ewere A, Diaz M, Wenzel P. TAZ responds to fluid shear stress to regulate the cell cycle. Cell Cycle. 2017;:1-21 pubmed publisher
Elosegui Artola A, Andreu I, Beedle A, Lezamiz A, Uroz M, Kosmalska A, et al. Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Cell. 2017;171:1397-1410.e14 pubmed publisher
Diamantopoulou Z, White G, Fadlullah M, Dreger M, Pickering K, Maltas J, et al. TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells. Cancer Cell. 2017;31:621-634.e6 pubmed publisher
Speight P, Kofler M, Szaszi K, Kapus A. Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGF?-regulated Smad3. Nat Commun. 2016;7:11642 pubmed publisher
Serrano I, McDonald P, Lock F, Muller W, Dedhar S. Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun. 2013;4:2976 pubmed publisher
product information
Cat.# :
560235
Brand :
BD Pharmingen
Name :
TAZ
Format :
Purified
Clone :
M2-616
Isotype :
Ms IgG 2b
React :
Hu
Conc :
0.5 mg/ml
Apps :
Bioimg , WB
Size :
0.1 mg
Status :
RUO
List Price :
278.00 USD
more info or order :
company information