product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
E-Cadherin
catalog :
560064
quantity :
100 Tests
price :
379.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
36/E-Cadherin
reactivity :
hamsters, human, mouse, rat, dog
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 49
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig s1d
Richardson R, Mitchell K, Hammond N, Mollo M, Kouwenhoven E, Wyatt N, et al. p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017;13:e1006828 pubmed publisher
  • immunohistochemistry; human; 2.5 ug/ml; tbl s3
Garrido Gomez T, Ona K, Kapidzic M, Gormley M, Simon C, Genbacev O, et al. Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion. Development. 2017;144:767-777 pubmed publisher
  • immunohistochemistry - paraffin section; dog; 0.8 ug/ml; fig 4k
  • western blot; dog; fig 2
Yokoyama N, Ohta H, Kagawa Y, Leela Arporn R, Dermlim A, Nisa K, et al. Expression of apical junction complex proteins in colorectal mucosa of miniature dachshunds with inflammatory colorectal polyps. J Vet Med Sci. 2017;79:456-463 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2
Bizzarro V, Belvedere R, Migliaro V, Romano E, Parente L, Petrella A. Hypoxia regulates ANXA1 expression to support prostate cancer cell invasion and aggressiveness. Cell Adh Migr. 2017;11:247-260 pubmed publisher
  • western blot; mouse; 1:10,000; fig 5
Schokrpur S, Hu J, Moughon D, Liu P, Lin L, Hermann K, et al. CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma. Sci Rep. 2016;6:29032 pubmed publisher
  • immunocytochemistry; hamsters; loading ...; fig s2
  • immunocytochemistry; human; loading ...; fig s3
  • immunocytochemistry; dog; loading ...; fig 1a
Chen C, Wang S, Chan P, Shen M, Chen H. Phosphorylation of E-cadherin at threonine 790 by protein kinase C? reduces ?-catenin binding and suppresses the function of E-cadherin. Oncotarget. 2016;7:37260-37276 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig s1i
Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nat Commun. 2016;7:11471 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 4
Choi V, Herrou J, Hecht A, Teoh W, Turner J, Crosson S, et al. Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice. Nat Med. 2016;22:563-7 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 3a
  • immunocytochemistry; mouse; 1:200; fig 3a
Hornsveld M, Tenhagen M, van de Ven R, Smits A, van Triest M, van Amersfoort M, et al. Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer. Cell Death Differ. 2016;23:1483-92 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig 2
Fiorino C, Harrison R. E-cadherin is important for cell differentiation during osteoclastogenesis. Bone. 2016;86:106-18 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 2a
Haikala H, Klefström J, Eilers M, Wiese K. MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures. Cell Cycle. 2016;15:316-23 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 1e
Howitt M, Lavoie S, Michaud M, Blum A, Tran S, Weinstock J, et al. Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut. Science. 2016;351:1329-33 pubmed publisher
  • western blot; human; 1:5000; fig 3
Maiden S, Petrova Y, Gumbiner B. Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model. PLoS ONE. 2016;11:e0148574 pubmed publisher
  • immunocytochemistry; human; loading ...
  • western blot; human; loading ...; fig s4b
Bowser J, Blackburn M, Shipley G, Molina J, Dunner K, Broaddus R. Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest. 2016;126:220-38 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250; fig 4
Faltermeier C, Drake J, Clark P, Smith B, Zong Y, Volpe C, et al. Functional screen identifies kinases driving prostate cancer visceral and bone metastasis. Proc Natl Acad Sci U S A. 2016;113:E172-81 pubmed publisher
  • western blot; human; fig 2
Widder M, Lützkendorf J, Caysa H, Unverzagt S, Wickenhauser C, Benndorf R, et al. Multipotent mesenchymal stromal cells promote tumor growth in distinct colorectal cancer cells by a β1-integrin-dependent mechanism. Int J Cancer. 2016;138:964-75 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; fig 2
Jung M, Ryu Y, Kang G. Investigation of the origin of stromal and endothelial cells at the desmoplastic interface in xenograft tumor in mice. Pathol Res Pract. 2015;211:925-30 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; tbl 2
Takahashi S, Kohashi K, Yamamoto H, Hirahashi M, Kumagai R, Takizawa N, et al. Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum. Hum Pathol. 2015;46:1257-66 pubmed publisher
  • immunocytochemistry; human
Burkhalter R, Westfall S, Liu Y, Stack M. Lysophosphatidic Acid Initiates Epithelial to Mesenchymal Transition and Induces β-Catenin-mediated Transcription in Epithelial Ovarian Carcinoma. J Biol Chem. 2015;290:22143-54 pubmed publisher
  • immunohistochemistry; mouse; fig 1e
Hernández P, Mahlakõiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F, et al. Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nat Immunol. 2015;16:698-707 pubmed publisher
  • immunohistochemistry; rat; 1:200
Tennakoon A, Izawa T, Wijesundera K, Katou Ichikawa C, Tanaka M, Golbar H, et al. Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA). Exp Mol Pathol. 2015;98:476-85 pubmed publisher
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Cai X, Dai Z, Reeves R, Caballero Benítez A, Duran K, Delrow J, et al. Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells. PLoS ONE. 2014;9:e108942 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Sako Kubota K, Tanaka N, Nagae S, Meng W, Takeichi M. Minus end-directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions. Mol Biol Cell. 2014;25:3851-60 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:35; fig 5
Wögenstein K, Szabo S, Lunova M, Wiche G, Haybaeck J, Strnad P, et al. Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules. PLoS ONE. 2014;9:e108323 pubmed publisher
  • immunohistochemistry; dog; fig 3
  • western blot; dog; fig 1
Ohta H, Sunden Y, Yokoyama N, Osuga T, Lim S, Tamura Y, et al. Expression of apical junction complex proteins in duodenal mucosa of dogs with inflammatory bowel disease. Am J Vet Res. 2014;75:746-51 pubmed publisher
  • immunocytochemistry; human; 1:200
Bassagañas S, Carvalho S, Dias A, Pérez Garay M, Ortiz M, Figueras J, et al. Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of ?2?1 integrin and E-cadherin function. PLoS ONE. 2014;9:e98595 pubmed publisher
  • immunohistochemistry; dog
Rossi G, Pengo G, Caldin M, Palumbo Piccionello A, Steiner J, Cohen N, et al. Comparison of microbiological, histological, and immunomodulatory parameters in response to treatment with either combination therapy with prednisone and metronidazole or probiotic VSL#3 strains in dogs with idiopathic inflammatory bowel disease. PLoS ONE. 2014;9:e94699 pubmed publisher
  • immunocytochemistry; human
Peitsch W, Doerflinger Y, Fischer Colbrie R, Huck V, Bauer A, Utikal J, et al. Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells. PLoS ONE. 2014;9:e89491 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300
Luo W, Yao K. Cancer stem cell characteristics, ALDH1 expression in the invasive front of nasopharyngeal carcinoma. Virchows Arch. 2014;464:35-43 pubmed publisher
  • immunohistochemistry; rat
Dawes L, Sugiyama Y, Lovicu F, Harris C, Shelley E, McAvoy J. Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism. Dev Biol. 2014;385:291-303 pubmed publisher
  • western blot; rat
Dawes L, Sugiyama Y, Tanedo A, Lovicu F, McAvoy J. Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation. Invest Ophthalmol Vis Sci. 2013;54:1582-90 pubmed publisher
  • western blot; dog; 0.05 ug/ml; loading ...; fig 1
  • immunohistochemistry; mouse; 0.8 ug/ml; loading ...; fig 2g
Ohta H, Yamaguchi T, Rajapakshage B, Murakami M, Sasaki N, Nakamura K, et al. Expression and subcellular localization of apical junction proteins in canine duodenal and colonic mucosa. Am J Vet Res. 2011;72:1046-51 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 3
Pigors M, Kiritsi D, Krümpelmann S, Wagner N, He Y, Podda M, et al. Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity. Hum Mol Genet. 2011;20:1811-9 pubmed publisher
  • immunoprecipitation; mouse; 1:2000; fig 1c
  • immunocytochemistry; mouse; 1:2000; loading ...; fig 1a
  • western blot; mouse; 1:2000; fig 6a
Gladden A, Hebert A, Schneeberger E, McClatchey A. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010;19:727-39 pubmed publisher
Biddy B, Kong W, Kamimoto K, Guo C, Waye S, Sun T, et al. Single-cell mapping of lineage and identity in direct reprogramming. Nature. 2018;564:219-224 pubmed publisher
Yamaguchi T, Sato H, Kobayashi T, Kato Itoh M, Goto T, Hara H, et al. An interspecies barrier to tetraploid complementation and chimera formation. Sci Rep. 2018;8:15289 pubmed publisher
Lima J, Carvalho J, Pinto Ribeiro I, Almeida C, Wengel J, Cerqueira L, et al. Targeting miR-9 in gastric cancer cells using locked nucleic acid oligonucleotides. BMC Mol Biol. 2018;19:6 pubmed publisher
Ferraretto A, Bottani M, De Luca P, Cornaghi L, Arnaboldi F, Maggioni M, et al. Morphofunctional properties of a differentiated Caco2/HT-29 co-culture as an in vitro model of human intestinal epithelium. Biosci Rep. 2018;38: pubmed publisher
Chockley P, Chen J, Chen G, Beer D, Standiford T, Keshamouni V. Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer. J Clin Invest. 2018;128:1384-1396 pubmed publisher
Yui S, Azzolin L, Maimets M, Pedersen M, Fordham R, Hansen S, et al. YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018;22:35-49.e7 pubmed publisher
Langer E, Kendsersky N, Daniel C, Kuziel G, Pelz C, Murphy K, et al. ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells. Oncogene. 2018;37:1005-1019 pubmed publisher
Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed publisher
Cooper J, Ou Y, McMillan E, Vaden R, Zaman A, Bodemann B, et al. TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer. Cancer Res. 2017;77:5077-5094 pubmed publisher
Jones G, D Orazio S. Monocytes Are the Predominant Cell Type Associated with Listeria monocytogenes in the Gut, but They Do Not Serve as an Intracellular Growth Niche. J Immunol. 2017;198:2796-2804 pubmed publisher
Chatterjee S, Saj A, Gocha T, Murphy M, Gonsalves F, Zhang X, et al. Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. J Cell Biol. 2015;211:39-51 pubmed publisher
Kato T, Oka K, Nakamura T, Ito A. Bronchioalveolar morphogenesis of human bronchial epithelial cells depending upon hepatocyte growth factor. J Cell Mol Med. 2015;19:2818-26 pubmed publisher
Nagai H, Sezaki M, Kakiguchi K, Nakaya Y, Lee H, Ladher R, et al. Cellular analysis of cleavage-stage chick embryos reveals hidden conservation in vertebrate early development. Development. 2015;142:1279-86 pubmed publisher
Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed publisher
Liebertz D, Lechner M, Masood R, Sinha U, Han J, Puri R, et al. Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1. Head Neck Oncol. 2010;2:5 pubmed publisher
product information
Cat.# :
560064
Brand :
BD Pharmingen
Name :
E-Cadherin
Format :
Alexa Fluor® 555
Clone :
36/E-Cadherin
Isotype :
Ms IgG 2a
React :
Hu , Ms , Rat , Dog
Apps :
Bioimg
Size :
100 Tests
Status :
RUO
List Price :
379.00 USD
more info or order :
company information