product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Caspase-3, Active Form
catalog :
559565
quantity :
25 µg
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C92-605
reactivity :
crab eating macaque, black ferret, human, mouse, pigs , zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 107
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; zebrafish ; 1:500; loading ...; fig s4a
Umans R, Pollock C, Mills W, Clark K, Pan Y, Sontheimer H. Using Zebrafish to Elucidate Glial-Vascular Interactions During CNS Development. Front Cell Dev Biol. 2021;9:654338 pubmed publisher
  • immunohistochemistry; pigs ; loading ...; fig 2b
  • immunohistochemistry; mouse; 1:500; loading ...; fig 7h
Völkner M, Kurth T, Schor J, Ebner L, Bardtke L, Kavak C, et al. Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture. Front Cell Dev Biol. 2021;9:645704 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1c
Qiu R, Wu J, Gudenas B, Northcott P, Wechsler Reya R, Lu Q. Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth. Commun Biol. 2021;4:552 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; loading ...; fig 1s2a
Ozcan G, Lim S, Leighton P, Allison W, Rihel J. Sleep is bi-directionally modified by amyloid beta oligomers. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 3a
Mamriev D, Abbas R, Klingler F, Kagan J, Kfir N, Donald A, et al. A small-molecule ARTS mimetic promotes apoptosis through degradation of both XIAP and Bcl-2. Cell Death Dis. 2020;11:483 pubmed publisher
  • immunohistochemistry - frozen section; black ferret; 1:300; loading ...; fig 4s1a
Matsumoto N, Tanaka S, Horiike T, Shinmyo Y, Kawasaki H. A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6e
Jachimowicz R, Beleggia F, Isensee J, Velpula B, Goergens J, Bustos M, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019;176:505-519.e22 pubmed publisher
  • flow cytometry; human; loading ...; fig 5c
Matsuda K, Kobayakawa T, Tsuchiya K, Hattori S, Nomura W, Gatanaga H, et al. Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal. J Biol Chem. 2019;294:116-129 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s3f
Maurya D, Bohm S, Alenius M. Hedgehog signaling regulates ciliary localization of mouse odorant receptors. Proc Natl Acad Sci U S A. 2017;114:E9386-E9394 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s6f
Jongbloets B, Lemstra S, Schellino R, Broekhoven M, Parkash J, Hellemons A, et al. Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors. Nat Commun. 2017;8:14666 pubmed publisher
  • flow cytometry; crab eating macaque; loading ...; fig 5d
Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3f
Engler J, Kursawe N, Solano M, Patas K, Wehrmann S, Heckmann N, et al. Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy. Proc Natl Acad Sci U S A. 2017;114:E181-E190 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; tbl 1
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2
Fogarty L, Song B, Suppiah Y, Hasan S, Martin H, Hogan S, et al. Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord. Mol Cell Neurosci. 2016;77:34-46 pubmed publisher
  • flow cytometry; human; 1:500; loading ...; fig 2c
  • flow cytometry; mouse; 1:500; loading ...; fig 2a, 5b
Ohmer M, Weber A, Sutter G, Ehrhardt K, Zimmermann A, Häcker G. Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis. Cell Death Dis. 2016;7:e2340 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:500; fig 6
Noonan H, Metelo A, Kamei C, Peterson R, Drummond I, Iliopoulos O. Loss of vhl in the zebrafish pronephros recapitulates early stages of human clear cell renal cell carcinoma. Dis Model Mech. 2016;9:873-84 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Cheng H, Gaddis D, Wu R, McSkimming C, Haynes L, Taylor A, et al. Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. J Clin Invest. 2016;126:3236-46 pubmed publisher
  • flow cytometry; human; loading ...; fig s3b
Gren S, Janciauskiene S, Sandeep S, Jonigk D, Kvist P, Gerwien J, et al. The protease inhibitor cystatin C down-regulates the release of IL-? and TNF-? in lipopolysaccharide activated monocytes. J Leukoc Biol. 2016;100:811-822 pubmed
  • immunohistochemistry - frozen section; mouse
Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss D, Frappart L, et al. Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis. Oncotarget. 2016;7:23006-18 pubmed publisher
  • flow cytometry; human; loading ...; fig 5e
Carrasco A, Fernández Bañares F, Pedrosa E, Salas A, Loras C, Rosinach M, et al. Regional Specialisation of T Cell Subsets and Apoptosis in the Human Gut Mucosa: Differences Between Ileum and Colon in Healthy Intestine and Inflammatory Bowel Diseases. J Crohns Colitis. 2016;10:1042-54 pubmed publisher
  • flow cytometry; human; fig 4
Nyhan M, O Donovan T, Boersma A, Wiemer E, McKenna S. MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells. BMC Cancer. 2016;16:101 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 6
Tadokoro T, Gao X, Hong C, Hotten D, Hogan B. BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors. Development. 2016;143:764-73 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 5
Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher
  • flow cytometry; mouse; fig 5a
Andzinski L, Kasnitz N, Stahnke S, Wu C, Gereke M, von Köckritz Blickwede M, et al. Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int J Cancer. 2016;138:1982-93 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 2
Login H, HÃ¥glin S, Berghard A, Bohm S. The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map. J Neurosci. 2015;35:13807-18 pubmed publisher
  • western blot; mouse; 1:1000; fig 7
Lee I, Jung K, Kim I, Lee H, Kim M, Yun S, et al. Human neural stem cells alleviate Alzheimer-like pathology in a mouse model. Mol Neurodegener. 2015;10:38 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:1000; fig 1
Wan X, Chen Z, Choi W, Gee H, Hildebrandt F, Zhou W. Loss of Epithelial Membrane Protein 2 Aggravates Podocyte Injury via Upregulation of Caveolin-1. J Am Soc Nephrol. 2016;27:1066-75 pubmed publisher
  • flow cytometry; mouse; fig s9a
Weigelin B, Bolaños E, Teijeira A, Martinez Forero I, Labiano S, Azpilikueta A, et al. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015;112:7551-6 pubmed publisher
  • western blot; human
Shi S, Wang Q, Xu J, Jang J, Padilla M, Nyunoya T, et al. Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis. Oncotarget. 2015;6:1640-51 pubmed
  • immunocytochemistry; zebrafish ; fig 5
  • immunohistochemistry; zebrafish ; 1:200
Yu J, Fox Z, Crimp J, Littleford H, Jowdry A, Jackman W. Hedgehog signaling regulates dental papilla formation and tooth size during zebrafish odontogenesis. Dev Dyn. 2015;244:577-90 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Jung H, Tatar A, Tu Y, Nobumori C, Yang S, Goulbourne C, et al. An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin. Mol Cell Biol. 2014;34:4534-44 pubmed publisher
  • western blot; human
Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey Bates E, et al. Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs. Int J Cancer. 2015;136:E51-61 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, et al. Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this. Development. 2014;141:3319-23 pubmed publisher
  • immunocytochemistry; human
Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed publisher
  • immunohistochemistry; zebrafish
Balci T, Prykhozhij S, Teh E, Da as S, McBride E, Liwski R, et al. A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis. Br J Haematol. 2014;167:48-61 pubmed publisher
  • western blot; human
Wang X, Stafford W, Mazurkiewicz M, Fryknäs M, Brjnic S, Zhang X, et al. The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death. Mol Pharmacol. 2014;85:932-45 pubmed publisher
  • immunocytochemistry; human
Petazzi P, Akizu N, Garcia A, Estarás C, Martinez de Paz A, Rodríguez Paredes M, et al. An increase in MECP2 dosage impairs neural tube formation. Neurobiol Dis. 2014;67:49-56 pubmed publisher
  • western blot; human
He W, Wang Q, Srinivasan B, Xu J, Padilla M, Li Z, et al. A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy. Oncogene. 2014;33:3004-13 pubmed publisher
  • western blot; human; fig 4
Xargay Torrent S, Lopez Guerra M, Saborit Villarroya I, Rosich L, Campo E, Roué G, et al. Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters. Clin Cancer Res. 2011;17:3956-68 pubmed publisher
  • immunohistochemistry - paraffin section; human
Koschny R, Ganten T, Sykora J, Haas T, Sprick M, Kolb A, et al. TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. Hepatology. 2007;45:649-58 pubmed
Warnes G. Flow cytometric detection of hyper-polarized mitochondria in regulated and accidental cell death processes. Apoptosis. 2020;25:548-557 pubmed publisher
Golenberg N, Squirrell J, Bennin D, Rindy J, Pistono P, Eliceiri K, et al. Citrullination regulates wound responses and tissue regeneration in zebrafish. J Cell Biol. 2020;219: pubmed publisher
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, et al. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Commun. 2019;10:4710 pubmed publisher
Mintz M, Felce J, Chou M, Mayya V, Xu Y, Shui J, et al. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. 2019;: pubmed publisher
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
Silva H, Bafica A, Rodrigues Luiz G, Chi J, Santos P, Reis B, et al. Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges. J Exp Med. 2019;216:786-806 pubmed publisher
Siekierska A, Stamberger H, Deconinck T, Oprescu S, Partoens M, Zhang Y, et al. Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish. Nat Commun. 2019;10:708 pubmed publisher
Chea L, Wyatt L, Gangadhara S, Moss B, Amara R. Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13R Delays Apoptosis and Enhances Humoral Responses. J Virol. 2019;93: pubmed publisher
Kennedy J, Steain M, Slobedman B, Abendroth A. Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus. J Virol. 2019;93: pubmed publisher
Chambers J, Poureetezadi S, Addiego A, Lahne M, Wingert R. ppargc1a controls nephron segmentation during zebrafish embryonic kidney ontogeny. elife. 2018;7: pubmed publisher
Hattori S, Matsuda K, Tsuchiya K, Gatanaga H, Oka S, Yoshimura K, et al. Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 Infection in vitro. Front Microbiol. 2018;9:2022 pubmed publisher
Chadwick M, Lane A, Thomas D, Smith A, White A, Davidson D, et al. Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma. Oncotarget. 2018;9:24750-24765 pubmed publisher
Robinson C, Chong A, Ashbrook A, Jeng G, Jin J, Chen H, et al. Male germ cells support long-term propagation of Zika virus. Nat Commun. 2018;9:2090 pubmed publisher
Feng L, Vujicic S, Dietrich M, Litbarg N, Setty S, Antoni A, et al. Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis. J Biol Chem. 2018;293:10245-10263 pubmed publisher
Than Trong E, Ortica Gatti S, Mella S, Nepal C, Alunni A, Bally Cuif L. Neural stem cell quiescence and stemness are molecularly distinct outputs of the Notch3 signalling cascade in the vertebrate adult brain. Development. 2018;145: pubmed publisher
Varelias A, Bunting M, Ormerod K, Koyama M, Olver S, Straube J, et al. Recipient mucosal-associated invariant T cells control GVHD within the colon. J Clin Invest. 2018;128:1919-1936 pubmed publisher
Zhang Y, Tech L, George L, Acs A, Durrett R, Hess H, et al. Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells. J Exp Med. 2018;215:1227-1243 pubmed publisher
Filipova D, Henry M, Rotshteyn T, Brunn A, Carstov M, Deckert M, et al. Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5. PLoS ONE. 2018;13:e0194428 pubmed publisher
Khan A, Carpenter B, Santos e Sousa P, Pospori C, Khorshed R, Griffin J, et al. Redirection to the bone marrow improves T cell persistence and antitumor functions. J Clin Invest. 2018;128:2010-2024 pubmed publisher
Dillenburg A, Ireland G, Holloway R, Davies C, Evans F, Swire M, et al. Activin receptors regulate the oligodendrocyte lineage in health and disease. Acta Neuropathol. 2018;135:887-906 pubmed publisher
Chua C, Epsi N, Leung E, Xuan S, Lei M, Li B, et al. Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation. elife. 2018;7: pubmed publisher
Clarke A, Riffelmacher T, Braas D, Cornall R, Simon A. B1a B cells require autophagy for metabolic homeostasis and self-renewal. J Exp Med. 2018;215:399-413 pubmed publisher
Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed publisher
Wonderlich E, Caroline A, McMillen C, Walters A, Reed D, Barratt Boyes S, et al. Peripheral Blood Biomarkers of Disease Outcome in a Monkey Model of Rift Valley Fever Encephalitis. J Virol. 2018;92: pubmed publisher
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed publisher
Singh P, Roukounakis A, Frank D, Kirschnek S, Das K, Neumann S, et al. Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis. Genes Dev. 2017;31:1754-1769 pubmed publisher
Mayer C, Gazumyan A, Kara E, Gitlin A, Golijanin J, Viant C, et al. The microanatomic segregation of selection by apoptosis in the germinal center. Science. 2017;358: pubmed publisher
Ferrara M, Sessa G, Fiore M, Bernard F, Asteriti I, Cundari E, et al. Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization. Oncogene. 2018;37:231-240 pubmed publisher
Zhu S, Zhang X, Weichert Leahey N, Dong Z, Zhang C, Lopez G, et al. LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer Cell. 2017;32:310-323.e5 pubmed publisher
Swan Z, Bouwer A, Wonderlich E, Barratt Boyes S. Persistent accumulation of gut macrophages with impaired phagocytic function correlates with SIV disease progression in macaques. Eur J Immunol. 2017;47:1925-1935 pubmed publisher
Kroeger P, Drummond B, Miceli R, McKernan M, Gerlach G, Marra A, et al. The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Dev Biol. 2017;428:148-163 pubmed publisher
Woodberry T, Loughland J, Minigo G, Burel J, Amante F, Piera K, et al. Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation. Infect Immun. 2017;85: pubmed publisher
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Kim N, Cha Y, Lee J, Lee S, Yang J, Yun J, et al. Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress. Nat Commun. 2017;8:14374 pubmed publisher
Cheng L, Ma J, Li J, Li D, Li G, Li F, et al. Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. J Clin Invest. 2017;127:269-279 pubmed publisher
Rydeen A, Waxman J. Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity. PLoS Biol. 2016;14:e2000504 pubmed publisher
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Wilfinger N, Austin S, Scheiber Mojdehkar B, Berger W, Reipert S, Praschberger M, et al. Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy. Oncotarget. 2016;7:1242-61 pubmed publisher
Poché R, Hsu C, McElwee M, Burns A, Dickinson M. Macrophages engulf endothelial cell membrane particles preceding pupillary membrane capillary regression. Dev Biol. 2015;403:30-42 pubmed publisher
Luyet C, Schulze K, Sayar B, Howald D, Müller E, Galichet A. Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris. PLoS ONE. 2015;10:e0119809 pubmed publisher
Ek C, D Angelo B, Baburamani A, Lehner C, Leverin A, Smith P, et al. Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia. J Cereb Blood Flow Metab. 2015;35:818-27 pubmed publisher
Slaats G, Ghosh A, Falke L, Le Corre S, Shaltiël I, van de Hoek G, et al. Nephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transition. PLoS Genet. 2014;10:e1004594 pubmed publisher
Tousif S, Singh D, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, et al. Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. J Biol Chem. 2014;289:30190-5 pubmed publisher
Cavalheiro G, Matos Rodrigues G, Gomes A, Rodrigues P, Martins R. c-Myc regulates cell proliferation during lens development. PLoS ONE. 2014;9:e87182 pubmed publisher
Kalko S, Paco S, Jou C, Rodríguez M, Meznaric M, Rogac M, et al. Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies. BMC Genomics. 2014;15:91 pubmed publisher
Némati F, De Montrion C, Lang G, Kraus Berthier L, Carita G, Sastre Garau X, et al. Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenografts. PLoS ONE. 2014;9:e80836 pubmed publisher
Whiteus C, Freitas C, Grutzendler J. Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period. Nature. 2014;505:407-11 pubmed publisher
O Shea L, Fair T, Hensey C. Aven is dynamically regulated during Xenopus oocyte maturation and is required for oocyte survival. Cell Death Dis. 2013;4:e908 pubmed publisher
Novorol C, Burkhardt J, Wood K, Iqbal A, Roque C, Coutts N, et al. Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression. Open Biol. 2013;3:130065 pubmed publisher
Khalaf Nazzal R, Bruel Jungerman E, Rio J, Bureau J, Irinopoulou T, Sumia I, et al. Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice. PLoS ONE. 2013;8:e72622 pubmed publisher
Viel T, Schelhaas S, Wagner S, Wachsmuth L, Schwegmann K, Kuhlmann M, et al. Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging. PLoS ONE. 2013;8:e67911 pubmed publisher
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Floyd S, Pacold M, Huang Q, Clarke S, Lam F, Cannell I, et al. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature. 2013;498:246-50 pubmed publisher
Boehm D, Mazurier C, Giarratana M, Darghouth D, Faussat A, Harmand L, et al. Caspase-3 is involved in the signalling in erythroid differentiation by targeting late progenitors. PLoS ONE. 2013;8:e62303 pubmed publisher
Hughes J, Piltz S, Rogers N, McAninch D, Rowley L, Thomas P. Mechanistic insight into the pathology of polyalanine expansion disorders revealed by a mouse model for X linked hypopituitarism. PLoS Genet. 2013;9:e1003290 pubmed publisher
Robu M, Zhang Y, Rhodes J. Rereplication in emi1-deficient zebrafish embryos occurs through a Cdh1-mediated pathway. PLoS ONE. 2012;7:e47658 pubmed publisher
Cai Y, Zhu H, Li J, Luo X, Patrylo P, Rose G, et al. Age-related intraneuronal elevation of ?II-spectrin breakdown product SBDP120 in rodent forebrain accelerates in 3×Tg-AD mice. PLoS ONE. 2012;7:e37599 pubmed publisher
Ponferrada V, Fan J, Vallance J, Hu S, Mamedova A, Rankin S, et al. CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis. PLoS ONE. 2012;7:e32635 pubmed publisher
Lee K, Tan J, Morris M, Rizzoti K, Hughes J, Cheah P, et al. Congenital hydrocephalus and abnormal subcommissural organ development in Sox3 transgenic mice. PLoS ONE. 2012;7:e29041 pubmed publisher
Chen C, Chu C, Chen T, Lee S, Shen C, Hsiao C. Establishment of a transgenic zebrafish line for superficial skin ablation and functional validation of apoptosis modulators in vivo. PLoS ONE. 2011;6:e20654 pubmed publisher
Rodriguez Mari A, Wilson C, Titus T, Canestro C, Bremiller R, Yan Y, et al. Roles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafish. PLoS Genet. 2011;7:e1001357 pubmed publisher
Ho J, Asagiri M, Hoffmann A, Ghosh G. NF-?B potentiates caspase independent hydrogen peroxide induced cell death. PLoS ONE. 2011;6:e16815 pubmed publisher
de Bruijn M, Raats D, Hoogwater F, van Houdt W, Cameron K, Medema J, et al. Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. Br J Cancer. 2010;102:1254-64 pubmed publisher
Forest V, Hadjeres R, Bertrand R, Jean François R. Optimisation and molecular signalling of apoptosis in sequential cryotherapy and chemotherapy combination in human A549 lung cancer xenografts in SCID mice. Br J Cancer. 2009;100:1896-902 pubmed publisher
Das G, Choi Y, Sicinski P, Levine E. Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells. Neural Dev. 2009;4:15 pubmed publisher
Meyer Bahlburg A, Andrews S, Yu K, Porcelli S, Rawlings D. Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med. 2008;205:155-68 pubmed publisher
Pardo J, Urban C, Galvez E, Ekert P, Muller U, Kwon Chung J, et al. The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice. J Cell Biol. 2006;174:509-19 pubmed
product information
Cat.# :
559565
Brand :
BD Pharmingen
Name :
Caspase-3, Active Form
Format :
Purified
Clone :
C92-605
Isotype :
Rab IgG
React :
Hu , Ms
Conc :
0.5 mg/ml
Apps :
Bioimg , ELISA , IC/FCM , IHC(Fr) , IP/WB
Size :
25 µg
Status :
RUO
more info or order :
company information