product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD140a
catalog :
558774
quantity :
0.1 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
APA5
reactivity :
mouse, rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, immunohistochemistry - free floating section, other
more info or order :
citations: 38
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig s2e
Wang Y, Su Y, Yu G, Wang X, Chen X, Yu B, et al. Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress. Adv Sci (Weinh). 2021;8:e2101181 pubmed publisher
  • other; mouse
Sherafat A, Pfeiffer F, Reiss A, Wood W, Nishiyama A. Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor. Nat Commun. 2021;12:2265 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6s2
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • immunocytochemistry; rat; 1:300; loading ...; fig s1g
Neumann B, Baror R, Zhao C, SEGEL M, Dietmann S, Rawji K, et al. Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells. Cell Stem Cell. 2019;25:473-485.e8 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s3a
Kim G, Rincon Fernandez Pacheco D, Saxon D, Yang A, Sabet S, Dutra Clarke M, et al. Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements. Cell. 2019;179:251-267.e24 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 4f
Wu R, Li A, Sun B, Sun J, Zhang J, Zhang T, et al. A novel m6A reader Prrc2a controls oligodendroglial specification and myelination. Cell Res. 2019;29:23-41 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1b
Zhao C, Dong C, Frah M, Deng Y, Marie C, Zhang F, et al. Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair. Dev Cell. 2018;45:753-768.e8 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 3e
Winkler C, Yabut O, Fregoso S, Gomez H, Dwyer B, Pleasure S, et al. The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog. J Neurosci. 2018;38:5237-5250 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1m
Kelenis D, Hart E, Edwards Fligner M, Johnson J, Vue T. ASCL1 regulates proliferation of NG2-glia in the embryonic and adult spinal cord. Glia. 2018;66:1862-1880 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 1b
  • immunocytochemistry; mouse; 1:500; fig s2a
Kuroda M, Muramatsu R, Maedera N, Koyama Y, Hamaguchi M, Fujimura H, et al. Peripherally derived FGF21 promotes remyelination in the central nervous system. J Clin Invest. 2017;127:3496-3509 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3b
Rux D, Song J, Swinehart I, Pineault K, Schlientz A, Trulik K, et al. Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells. Dev Cell. 2016;39:653-666 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 8
Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2? signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 1h
Nagao M, Ogata T, Sawada Y, Gotoh Y. Zbtb20 promotes astrocytogenesis during neocortical development. Nat Commun. 2016;7:11102 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1g
Zhao C, Deng Y, Liu L, Yu K, Zhang L, Wang H, et al. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nat Commun. 2016;7:10883 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, et al. Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth. Nat Immunol. 2016;17:159-68 pubmed publisher
  • immunohistochemistry; mouse; 1:200
Peckham H, Giuffrida L, Wood R, Gonsalvez D, Ferner A, Kilpatrick T, et al. Fyn is an intermediate kinase that BDNF utilizes to promote oligodendrocyte myelination. Glia. 2016;64:255-69 pubmed publisher
  • flow cytometry; mouse; fig 1
Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, et al. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015;212:905-25 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 1
Liu W, Zhou H, Liu L, Zhao C, Deng Y, Chen L, et al. Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region. Neurobiol Dis. 2015;77:106-16 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 3
Giera S, Deng Y, Luo R, Ackerman S, Mogha A, Monk K, et al. The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015;6:6121 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig s4b
Umberger N, Caspary T. Ciliary transport regulates PDGF-AA/αα signaling via elevated mammalian target of rapamycin signaling and diminished PP2A activity. Mol Biol Cell. 2015;26:350-8 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50
Wahl S, McLane L, Bercury K, Macklin W, Wood T. Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination. J Neurosci. 2014;34:4453-65 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:100
McQueen J, Reimer M, Holland P, Manso Y, McLaughlin M, Fowler J, et al. Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion. PLoS ONE. 2014;9:e87227 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Hagiwara K, Obayashi T, Sakayori N, Yamanishi E, Hayashi R, Osumi N, et al. Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells. PLoS ONE. 2014;9:e84072 pubmed publisher
  • immunohistochemistry; mouse; 1:800
Khalaf Nazzal R, Bruel Jungerman E, Rio J, Bureau J, Irinopoulou T, Sumia I, et al. Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice. PLoS ONE. 2013;8:e72622 pubmed publisher
  • immunohistochemistry; mouse; 1:250
Viganò F, Mobius W, Gotz M, Dimou L. Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain. Nat Neurosci. 2013;16:1370-2 pubmed publisher
  • immunocytochemistry; rat
Pendleton J, Shamblott M, Gary D, Belegu V, Hurtado A, Malone M, et al. Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTP?. Exp Neurol. 2013;247:113-21 pubmed publisher
Wei H, Dong X, You Y, Hai B, Duran R, Wu X, et al. OLIG2 regulates lncRNAs and its own expression during oligodendrocyte lineage formation. BMC Biol. 2021;19:132 pubmed publisher
Tripathi A, Volsko C, Garcia J, Agirre E, Allan K, Tesar P, et al. Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination. Cell Rep. 2019;29:904-919.e9 pubmed publisher
Rungta R, Chaigneau E, Osmanski B, Charpak S. Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia. Neuron. 2018;99:362-375.e4 pubmed publisher
González Fernández E, Jeong H, Fukaya M, Kim H, Khawaja R, Srivastava I, et al. PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling. elife. 2018;7: pubmed publisher
Kuipers H, Yoon J, van Horssen J, Han M, Bollyky P, Palmer T, et al. Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination. Proc Natl Acad Sci U S A. 2017;114:E1745-E1754 pubmed publisher
Fancy S, Harrington E, Baranzini S, Silbereis J, Shiow L, Yuen T, et al. Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nat Neurosci. 2014;17:506-12 pubmed publisher
Chertoff M, Shrivastava K, Gonzalez B, Acarin L, Gimenez Llort L. Differential modulation of TREM2 protein during postnatal brain development in mice. PLoS ONE. 2013;8:e72083 pubmed publisher
Bujalka H, Koenning M, Jackson S, Perreau V, Pope B, Hay C, et al. MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol. 2013;11:e1001625 pubmed publisher
Rostovskaya M, Anastassiadis K. Differential expression of surface markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment. PLoS ONE. 2012;7:e51221 pubmed publisher
Zhang L, Yu W, Schroedter I, Kong J, Vrontakis M. Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model. PLoS ONE. 2012;7:e33901 pubmed publisher
Fancy S, Harrington E, Yuen T, Silbereis J, Zhao C, Baranzini S, et al. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci. 2011;14:1009-16 pubmed publisher
Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, et al. Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. J Exp Med. 2001;193:621-30 pubmed
product information
Cat.# :
558774
Brand :
BD Pharmingen
Name :
CD140a
Format :
Purified
Clone :
APA5
Isotype :
Rat IgG 2a
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.1 mg
Status :
RUO
more info or order :
company information