product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Cytochrome c
catalog :
558700
quantity :
100 Tests
price :
379.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6H2.B4
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 2b
Akabane S, Matsuzaki K, Yamashita S, Arai K, Okatsu K, Kanki T, et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy. J Biol Chem. 2016;291:16162-74 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 5
Winter L, Kuznetsov A, Grimm M, Zeöld A, Fischer I, Wiche G. Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle. Hum Mol Genet. 2015;24:4530-44 pubmed publisher
  • western blot; human
Morita A, Ariyasu S, Wang B, Asanuma T, Onoda T, Sawa A, et al. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation. Biochem Biophys Res Commun. 2014;450:1498-504 pubmed publisher
  • immunocytochemistry; human
Landry M, Champagne C, Boulanger M, Jetté A, Fuchs M, Dziengelewski C, et al. A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases. J Biol Chem. 2014;289:2230-49 pubmed publisher
Zhou J, Liu S, Wang Y, Dai W, Zou H, Wang S, et al. Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma. Mol Cancer. 2019;18:159 pubmed publisher
Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
Mukherjee A, Patra U, Bhowmick R, Chawla Sarkar M. Rotaviral nonstructural protein 4 triggers dynamin-related protein 1-dependent mitochondrial fragmentation during infection. Cell Microbiol. 2018;20:e12831 pubmed publisher
Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher
Chattaragada M, Riganti C, Sassoe M, Principe M, Santamorena M, Roux C, et al. FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis. Oncogene. 2018;37:697-709 pubmed publisher
Skrott Z, Mistrik M, Andersen K, Friis S, Majera D, Gursky J, et al. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017;552:194-199 pubmed publisher
Lee J, Kim Y, Liu T, Hwang Y, Hyeon S, Im H, et al. SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease. Aging Cell. 2017;: pubmed publisher
Dang E, McDonald J, Russell D, Cyster J. Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation. Cell. 2017;171:1057-1071.e11 pubmed publisher
Cakir Z, Funk K, Lauterwasser J, Todt F, Zerbes R, Oelgeklaus A, et al. Parkin promotes proteasomal degradation of misregulated BAX. J Cell Sci. 2017;130:2903-2913 pubmed publisher
Westrate L, Drocco J, Martin K, Hlavacek W, Mackeigan J. Mitochondrial morphological features are associated with fission and fusion events. PLoS ONE. 2014;9:e95265 pubmed publisher
Yamano K, Fogel A, Wang C, van der Bliek A, Youle R. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. elife. 2014;3:e01612 pubmed publisher
Goller T, Seibold U, Kremmer E, Voos W, Kolanus W. Atad3 function is essential for early post-implantation development in the mouse. PLoS ONE. 2013;8:e54799 pubmed publisher
Tait S, de Vries E, Maas C, Keller A, D Santos C, Borst J. Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. J Cell Biol. 2007;179:1453-66 pubmed publisher
Pardo J, Urban C, Galvez E, Ekert P, Muller U, Kwon Chung J, et al. The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice. J Cell Biol. 2006;174:509-19 pubmed
Todorovic V, Chen C, Hay N, Lau L. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. J Cell Biol. 2005;171:559-68 pubmed
Niemann A, Ruegg M, La Padula V, Schenone A, Suter U. Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J Cell Biol. 2005;170:1067-78 pubmed
Berliocchi L, Fava E, Leist M, Horvat V, Dinsdale D, Read D, et al. Botulinum neurotoxin C initiates two different programs for neurite degeneration and neuronal apoptosis. J Cell Biol. 2005;168:607-18 pubmed
Pozniakovsky A, Knorre D, Markova O, Hyman A, Skulachev V, Severin F. Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast. J Cell Biol. 2005;168:257-69 pubmed
Karbowski M, Jeong S, Youle R. Endophilin B1 is required for the maintenance of mitochondrial morphology. J Cell Biol. 2004;166:1027-39 pubmed
Rehm M, Dussmann H, Prehn J. Real-time single cell analysis of Smac/DIABLO release during apoptosis. J Cell Biol. 2003;162:1031-43 pubmed
Reimertz C, Kogel D, Rami A, Chittenden T, Prehn J. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol. 2003;162:587-97 pubmed
Boya P, Andreau K, Poncet D, Zamzami N, Perfettini J, Metivier D, et al. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med. 2003;197:1323-34 pubmed
Murphy B, O Neill A, Adrain C, Watson R, Martin S. The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome C. J Exp Med. 2003;197:625-32 pubmed
Clarke M, Savill J, Jones D, Noble B, Brown S. Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death. J Cell Biol. 2003;160:577-87 pubmed
Arnoult D, Parone P, Martinou J, Antonsson B, Estaquier J, Ameisen J. Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli. J Cell Biol. 2002;159:923-9 pubmed
Robert A, Miron M, Champagne C, Gingras M, Branton P, Lavoie J. Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein. J Cell Biol. 2002;158:519-28 pubmed
Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol. 2002;157:455-68 pubmed
Dorstyn L, Read S, Cakouros D, Huh J, Hay B, Kumar S. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. J Cell Biol. 2002;156:1089-98 pubmed
Castedo M, Ferri K, Blanco J, Roumier T, Larochette N, Barretina J, et al. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J Exp Med. 2001;194:1097-110 pubmed
Ferri K, Jacotot E, Blanco J, Este J, Zamzami N, Susin S, et al. Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases. J Exp Med. 2000;192:1081-92 pubmed
Jacotot E, Ravagnan L, Loeffler M, Ferri K, Vieira H, Zamzami N, et al. The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med. 2000;191:33-46 pubmed
product information
Cat.# :
558700
Brand :
BD Pharmingen
Name :
Cytochrome c
Format :
Alexa Fluor® 555
Clone :
6H2.B4
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat
Apps :
Bioimg
Size :
100 Tests
Status :
RUO
List Price :
379.00 USD
more info or order :
company information