product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
SREBP-2
catalog :
557037
quantity :
0.1 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IgG-1C6
reactivity :
human
application :
western blot, immunoprecipitation, chromatin immunoprecipitation
more info or order :
BD Biosciences product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 2e
Lebeau P, Byun J, Platko K, Saliba P, Sguazzin M, Macdonald M, et al. Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance. Nat Commun. 2022;13:770 pubmed publisher
  • western blot; human; 1:250; loading ...; fig 5g
Aregger M, Lawson K, Billmann M, Costanzo M, Tong A, Chan K, et al. Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism. Nat Metab. 2020;2:499-513 pubmed publisher
  • western blot; human; loading ...; fig 4a
Göbel A, Breining D, Rauner M, Hofbauer L, Rachner T. Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells. Cell Death Dis. 2019;10:91 pubmed publisher
  • chromatin immunoprecipitation; human
Garver W, Jelinek D, Francis G, Murphy B. The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts. J Lipid Res. 2008;49:1090-102 pubmed publisher
Goedeke L, Canfrán Duque A, Rotllan N, Chaube B, Thompson B, Lee R, et al. MMAB promotes negative feedback control of cholesterol homeostasis. Nat Commun. 2021;12:6448 pubmed publisher
product information
Cat.# :
557037
Brand :
BD Pharmingen
Name :
SREBP-2
Format :
Purified
Clone :
IgG-1C6
Isotype :
Ms IgG 1
React :
Hu
Conc :
0.5 mg/ml
Apps :
IP , WB
Size :
0.1 mg
Status :
RUO
more info or order :
BD Biosciences product webpage
company information