product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
SREBP-1
catalog :
557036
quantity :
0.1 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IgG-2A4
reactivity :
human, mouse
application :
western blot, immunoprecipitation, western blot knockout validation
more info or order :
BD Biosciences product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig s6
Jang H, Lee G, Selby C, Lee G, Jeon Y, Lee J, et al. SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nat Commun. 2016;7:12180 pubmed publisher
  • western blot; human; loading ...; fig 1f
Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed publisher
  • western blot; human; loading ...; fig s9d
Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Stein S, Lemos V, Xu P, Demagny H, Wang X, Ryu D, et al. Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease. J Clin Invest. 2017;127:583-592 pubmed publisher
  • western blot; human; fig 3k
Geng F, Cheng X, Wu X, Yoo J, Cheng C, Guo J, et al. Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clin Cancer Res. 2016;22:5337-5348 pubmed
  • western blot; human; loading ...; fig 7c
Belkaid A, Duguay S, Ouellette R, Surette M. 17β-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cells. BMC Cancer. 2015;15:440 pubmed publisher
Wu S, Naar A. SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Sci Rep. 2019;9:10369 pubmed publisher
Lee J, Jeon Y, Lee K, Lee H, Park J, Jang H, et al. RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer. Mol Cell Biol. 2017;37: pubmed publisher
Yu Y, Pierciey F, Maguire T, Alwine J. PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection. PLoS Pathog. 2013;9:e1003266 pubmed publisher
Le Martelot G, Claudel T, Gatfield D, Schaad O, Kornmann B, Lo Sasso G, et al. REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol. 2009;7:e1000181 pubmed publisher
product information
Cat.# :
557036
Brand :
BD Pharmingen
Name :
SREBP-1
Format :
Purified
Clone :
IgG-2A4
Isotype :
Ms IgG 1
React :
Hu , Ham
Conc :
0.5 mg/ml
Apps :
IP , WB
Size :
0.1 mg
Status :
RUO
more info or order :
BD Biosciences product webpage
company information