product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
DNA Topoisomerase I
catalog :
556597
quantity :
0.1 mg
price :
270.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C-21
reactivity :
human, mouse
application :
western blot, immunohistochemistry, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
BD Biosciences product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 3
  • immunohistochemistry; human; fig 3
  • western blot; human; fig 3
Zhang H, Zhang Y, Yasukawa T, Dalla Rosa I, Khiati S, Pommier Y. Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases II? and II? in vertebrate mitochondria. Nucleic Acids Res. 2014;42:7259-67 pubmed publisher
  • western blot; human; fig 4
Ribeyre C, Zellweger R, Chauvin M, Bec N, Larroque C, Lopes M, et al. Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks. Cell Rep. 2016;15:300-9 pubmed publisher
  • western blot; human; fig 2
Vincent A, Berthel E, Dacheux E, Magnard C, Venezia N. BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28. Biochem J. 2016;473:949-60 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2
Kaur G, Reinhart R, Monks A, Evans D, Morris J, Polley E, et al. Bromodomain and hedgehog pathway targets in small cell lung cancer. Cancer Lett. 2016;371:225-39 pubmed publisher
  • western blot; mouse
Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
  • western blot; human; 1:2000
Pardee T, Stadelman K, Jennings Gee J, Caudell D, Gmeiner W. The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells. Oncotarget. 2014;5:4170-9 pubmed
Misiak M, Heldt M, Szeligowska M, Mazzini S, Scaglioni L, Grabe G, et al. Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7. Oncotarget. 2017;8:105137-105154 pubmed publisher
Khiati S, Dalla Rosa I, Sourbier C, Ma X, Rao V, Neckers L, et al. Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity. Clin Cancer Res. 2014;20:4873-81 pubmed publisher
Orr S, Boutz D, Wang R, Chronis C, Lea N, Thayaparan T, et al. Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry. Mol Syst Biol. 2012;8:573 pubmed publisher
Gundry R, Raginski K, Tarasova Y, Tchernyshyov I, Bausch Fluck D, Elliott S, et al. The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. Mol Cell Proteomics. 2009;8:2555-69 pubmed publisher
product information
Cat.# :
556597
Brand :
BD Pharmingen
Name :
DNA Topoisomerase I
Format :
Purified
Clone :
C-21
Isotype :
Ms IgM
React :
Hu
Conc :
0.5 mg/ml
Apps :
WB
Size :
0.1 mg
Status :
RUO
List Price :
270.00 USD
more info or order :
BD Biosciences product webpage
company information