product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Bax
catalog :
556467
quantity :
0.1 mg
price :
268.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6A7
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:100
  • western blot; human; loading ...; fig 4e
Brasacchio D, Alsop A, Noori T, Lufti M, Iyer S, Simpson K, et al. Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization. Cell Death Differ. 2017;24:961-970 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 4c
  • western blot; human; loading ...; fig 4c
Matsuura K, Huang N, Cocce K, Zhang L, Kornbluth S. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin. Oncogene. 2017;36:1698-1706 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3a
Lavik A, Zhong F, Chang M, Greenberg E, Choudhary Y, Smith M, et al. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2. Oncotarget. 2015;6:27388-402 pubmed publisher
  • western blot; rat; fig 10
Matsumoto T, Urushido M, Ide H, Ishihara M, Hamada Ode K, Shimamura Y, et al. Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury. PLoS ONE. 2015;10:e0126229 pubmed publisher
  • immunoprecipitation; human
  • immunocytochemistry; human; fig 4b
Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed publisher
  • western blot; human; 1:500
Han M, Woo S, Min K, Kim S, Park J, Kim D, et al. 6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression. Chem Biol Interact. 2015;228:69-78 pubmed publisher
  • western blot; human
Brinkmann K, Hombach A, Seeger J, Wagner Stippich D, Klubertz D, Kronke M, et al. Second mitochondria-derived activator of caspase (SMAC) mimetic potentiates tumor susceptibility toward natural killer cell-mediated killing. Leuk Lymphoma. 2014;55:645-51 pubmed publisher
  • flow cytometry; human
Xargay Torrent S, Lopez Guerra M, Saborit Villarroya I, Rosich L, Campo E, Roué G, et al. Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters. Clin Cancer Res. 2011;17:3956-68 pubmed publisher
Han M, Min K, Woo S, Seo B, Kwon T. Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells. Oncotarget. 2016;7:65707-65720 pubmed publisher
Yu W, Bonnet M, Farso M, Ma K, Chabot J, Martin E, et al. The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer's disease. BMC Neurosci. 2014;15:73 pubmed publisher
Balmer D, Emery M, Andreux P, Auwerx J, Ginet V, Puyal J, et al. Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells. PLoS ONE. 2013;8:e74162 pubmed publisher
Koziel K, Smigelskaite J, Drasche A, Enthammer M, Ashraf M, Khalid S, et al. RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins. Exp Cell Res. 2013;319:2728-38 pubmed publisher
van Dijk M, Halpin McCormick A, Sessler T, Samali A, Szegezdi E. Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways. Cell Death Dis. 2013;4:e702 pubmed publisher
Razandi M, Pedram A, Jordan V, Fuqua S, Levin E. Tamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer. Oncogene. 2013;32:3274-85 pubmed publisher
Stratos I, Li Z, Rotter R, Herlyn P, Mittlmeier T, Vollmar B. Inhibition of caspase mediated apoptosis restores muscle function after crush injury in rat skeletal muscle. Apoptosis. 2012;17:269-77 pubmed publisher
Mahmoudi S, Henriksson S, Farnebo L, Roberg K, Farnebo M. WRAP53 promotes cancer cell survival and is a potential target for cancer therapy. Cell Death Dis. 2011;2:e114 pubmed publisher
Todorovic V, Chen C, Hay N, Lau L. The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts. J Cell Biol. 2005;171:559-68 pubmed
Andoniou C, Andrews D, Manzur M, Ricciardi Castagnoli P, Degli Esposti M. A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells. J Cell Biol. 2004;166:827-37 pubmed
Zong W, Li C, Hatzivassiliou G, Lindsten T, Yu Q, Yuan J, et al. Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol. 2003;162:59-69 pubmed
Boya P, Andreau K, Poncet D, Zamzami N, Perfettini J, Metivier D, et al. Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med. 2003;197:1323-34 pubmed
Zhang Y, McLaughlin R, Goodyer C, LeBlanc A. Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons. J Cell Biol. 2002;156:519-29 pubmed
Castedo M, Ferri K, Blanco J, Roumier T, Larochette N, Barretina J, et al. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J Exp Med. 2001;194:1097-110 pubmed
product information
Cat.# :
556467
Brand :
BD Pharmingen
Name :
Bax
Format :
Purified
Clone :
6A7
Isotype :
Ms IgG 1
React :
Hu , Ms , Rat
Conc :
0.5 mg/ml
Apps :
WB
Size :
0.1 mg
Status :
RUO
List Price :
268.00 USD
more info or order :
company information
BD Biosciences