Nakamura Y, Dryanovski D, Kimura Y, Jackson S, Woods A, Yasui Y, et al. Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion. elife. 2019;8: pubmed publisher

Puri C, Vicinanza M, Ashkenazi A, Gratian M, Zhang Q, Bento C, et al. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Dev Cell. 2018;45:114-131.e8 pubmed publisher

McArthur K, Whitehead L, Heddleston J, Li L, Padman B, Oorschot V, et al. BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science. 2018;359: pubmed publisher

Sorokina I, Denisenko T, Imreh G, Tyurin Kuzmin P, Kaminskyy V, Gogvadze V, et al. Involvement of autophagy in the outcome of mitotic catastrophe. Sci Rep. 2017;7:14571 pubmed publisher

Koh J, Hancock C, Terada S, Higashida K, Holloszy J, Han D. PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise. Cell Metab. 2017;25:1176-1185.e5 pubmed publisher

Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, et al. Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death. J Biol Chem. 2017;292:4727-4742 pubmed publisher

Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed publisher

Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed publisher

Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher

Kang Y, Baker M, Liem M, Louber J, McKenzie M, Atukorala I, et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. elife. 2016;5: pubmed publisher

Welchen E, Schmitz J, Fuchs P, Garcia L, Wagner S, Wienstroer J, et al. d-Lactate Dehydrogenase Links Methylglyoxal Degradation and Electron Transport through Cytochrome c. Plant Physiol. 2016;172:901-912 pubmed

Megyesi J, Tarcsafalvi A, Seng N, Hodeify R, Price P. Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak. Cell Death Discov. 2016;2: pubmed

Molla B, Riveiro F, Bolinches Amorós A, Muñoz Lasso D, Palau F, Gonzalez Cabo P. Two different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich's ataxia. Dis Model Mech. 2016;9:647-57 pubmed publisher

Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed publisher

Wang J, Goetsch L, Tucker L, Zhang Q, Gonzalez A, Vaidya K, et al. Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification. BMC Cancer. 2016;16:105 pubmed publisher

Cousin F, Jouan Lanhouet S, Théret N, Brenner C, Jouan E, Le Moigne Muller G, et al. The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer. Oncotarget. 2016;7:7161-78 pubmed publisher

Cloonan S, Glass K, Laucho Contreras M, Bhashyam A, Cervo M, Pabón M, et al. Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nat Med. 2016;22:163-74 pubmed publisher

Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed publisher

Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed publisher

Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed publisher

Ambroise G, Portier A, Roders N, Arnoult D, Vazquez A. Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells. Oncotarget. 2015;6:38181-94 pubmed publisher

Fentz J, Kjøbsted R, Kristensen C, Hingst J, Birk J, Gudiksen A, et al. AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle. Am J Physiol Endocrinol Metab. 2015;309:E900-14 pubmed publisher

Naghdi S, Várnai P, Hajnóczky G. Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis. Proc Natl Acad Sci U S A. 2015;112:E5590-9 pubmed publisher

Matsuda S, Adachi J, Ihara M, Tanuma N, Shima H, Kakizuka A, et al. Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor. Nucleic Acids Res. 2016;44:636-47 pubmed publisher

Zhu X, Wang K, Zhang K, Tan X, Wu Z, Sun S, et al. Tetramethylpyrazine Protects Retinal Capillary Endothelial Cells (TR-iBRB2) against IL-1β-Induced Nitrative/Oxidative Stress. Int J Mol Sci. 2015;16:21775-90 pubmed publisher

Sereni F, Dal Monte M, Filippi L, Bagnoli P. Role of host β1- and β2-adrenergic receptors in a murine model of B16 melanoma: functional involvement of β3-adrenergic receptors. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:1317-31 pubmed publisher

Huang C, Lee C, Lin H, Chen M, Lin C, Chang J. Autophagy-Regulated ROS from Xanthine Oxidase Acts as an Early Effector for Triggering Late Mitochondria-Dependent Apoptosis in Cathepsin S-Targeted Tumor Cells. PLoS ONE. 2015;10:e0128045 pubmed publisher

Loureiro R, Magalhães Novais S, Mesquita K, Baldeiras I, Sousa I, Tavares L, et al. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015;6:17081-96 pubmed

Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed publisher

Yang N, Gilman P, Mirzayans R, Sun X, Touret N, Weinfeld M, et al. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound. PLoS ONE. 2015;10:e0125381 pubmed publisher

Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher

Brandauer J, Andersen M, Kellezi H, Risis S, Frøsig C, Vienberg S, et al. AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD. Front Physiol. 2015;6:85 pubmed publisher

Kao Y, Chang B, Liang J, Tsai H, Lee Y, Lin R, et al. Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid β-oxidation. PLoS Pathog. 2015;11:e1004750 pubmed publisher

Zhang Q, Kuang H, Chen C, Yan J, Do Umehara H, Liu X, et al. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nat Immunol. 2015;16:458-66 pubmed publisher

Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed publisher

Rayavarapu R, Heiden B, Pagani N, Shaw M, Shuff S, Zhang S, et al. The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment. J Biol Chem. 2015;290:8722-33 pubmed publisher

Han M, Woo S, Min K, Kim S, Park J, Kim D, et al. 6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression. Chem Biol Interact. 2015;228:69-78 pubmed publisher

Bertolin G, Jacoupy M, Traver S, Ferrando Miguel R, Saint Georges T, Grenier K, et al. Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10. Cell Death Differ. 2015;22:1563-76 pubmed publisher

Sanderson T, Raghunayakula S, Kumar R. Release of mitochondrial Opa1 following oxidative stress in HT22 cells. Mol Cell Neurosci. 2015;64:116-22 pubmed publisher

Zhou L, Park S, Xu L, Xia X, Ye J, Su L, et al. Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice. Nat Commun. 2015;6:5949 pubmed publisher

Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed publisher

Nie C, Luo Y, Zhao X, Luo N, Tong A, Liu X, et al. Caspase-9 mediates Puma activation in UCN-01-induced apoptosis. Cell Death Dis. 2014;5:e1495 pubmed publisher

Geserick P, Wang J, Feoktistova M, Leverkus M. The ratio of Mcl-1 and Noxa determines ABT737 resistance in squamous cell carcinoma of the skin. Cell Death Dis. 2014;5:e1412 pubmed publisher

White A, Philp A, Fridolfsson H, Schilling J, Murphy A, Hamilton D, et al. High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression. Am J Physiol Endocrinol Metab. 2014;307:E764-72 pubmed publisher

Burman J, Itsara L, Kayser E, Suthammarak W, Wang A, Kaeberlein M, et al. A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer. Dis Model Mech. 2014;7:1165-74 pubmed publisher

Bai L, Chen J, McEachern D, Liu L, Zhou H, Aguilar A, et al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS ONE. 2014;9:e99404 pubmed publisher

Thomas R, Andrews L, Burman J, Lin W, Pallanck L. PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix. PLoS Genet. 2014;10:e1004279 pubmed publisher

Olesen J, Gliemann L, Biensø R, Schmidt J, Hellsten Y, Pilegaard H. Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men. J Physiol. 2014;592:1873-86 pubmed publisher

Chen M, Zhang Y, Yu V, Chong Y, Yoshioka T, Ge R. Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction. Cell Death Differ. 2014;21:797-810 pubmed publisher

Xavier J, Morgado A, Sola S, Rodrigues C. Mitochondrial translocation of p53 modulates neuronal fate by preventing differentiation-induced mitochondrial stress. Antioxid Redox Signal. 2014;21:1009-24 pubmed publisher

Landry M, Champagne C, Boulanger M, Jetté A, Fuchs M, Dziengelewski C, et al. A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases. J Biol Chem. 2014;289:2230-49 pubmed publisher

Clerc P, Ge S, Hwang H, Waddell J, Roelofs B, Karbowski M, et al. Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes. Br J Pharmacol. 2014;171:1988-99 pubmed publisher

Yoshioka H, Katsu M, Sakata H, Okami N, Wakai T, Kinouchi H, et al. The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J Cereb Blood Flow Metab. 2013;33:1658-65 pubmed publisher

Mobasher M, Gonzalez Rodriguez A, Santamaria B, Ramos S, Martin M, Goya L, et al. Protein tyrosine phosphatase 1B modulates GSK3?/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. Cell Death Dis. 2013;4:e626 pubmed publisher

Kristensen J, Larsen S, Helge J, Dela F, Wojtaszewski J. Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS ONE. 2013;8:e53533 pubmed publisher

Liu C, Chen C, Huang A, Li J. Subamolide A, a component isolated from Cinnamomum subavenium, induces apoptosis mediated by mitochondria-dependent, p53 and ERK1/2 pathways in human urothelial carcinoma cell line NTUB1. J Ethnopharmacol. 2011;137:503-11 pubmed publisher

Son J, Varadarajan S, Bratton S. TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1. Cell Death Differ. 2010;17:1288-301 pubmed publisher

Yee K, Wilkinson S, James J, Ryan K, Vousden K. PUMA- and Bax-induced autophagy contributes to apoptosis. Cell Death Differ. 2009;16:1135-45 pubmed publisher

Liu J, Zhou W, Li S, Sun Z, Lin B, Lang Y, et al. Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues. Cancer Res. 2008;68:8871-80 pubmed publisher

Rieger J, Lemke D, Maurer G, Weiler M, Frank B, Tabatabai G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106:2436-48 pubmed publisher

Wolff S, Erster S, Palacios G, Moll U. p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Res. 2008;18:733-44 pubmed publisher

Martin Latil S, Mousson L, Autret A, Colbere Garapin F, Blondel B. Bax is activated during rotavirus-induced apoptosis through the mitochondrial pathway. J Virol. 2007;81:4457-64 pubmed

Chin H, Li M, Tan I, Ninnis R, Reljic B, Scicluna K, et al. VDAC2 enables BAX to mediate apoptosis and limit tumor development. Nat Commun. 2018;9:4976 pubmed publisher

Kale J, Kutuk O, Brito G, Andrews T, Leber B, Letai A, et al. Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. EMBO Rep. 2018;19: pubmed publisher

Steenbeek S, Pham T, de Ligt J, Zomer A, Knol J, Piersma S, et al. Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. EMBO J. 2018;37: pubmed publisher

Niescier R, Hong K, Park D, MIN K. MCU Interacts with Miro1 to Modulate Mitochondrial Functions in Neurons. J Neurosci. 2018;38:4666-4677 pubmed publisher

Debernardi J, Hollville E, Lipinski M, Wiels J, Robert A. Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt's lymphoma cells. Oncogene. 2018;37:2410-2421 pubmed publisher

Lu C, Yang D, Sabbatini M, Colby A, Grinstaff M, Oberlies N, et al. Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells. BMC Cancer. 2018;18:149 pubmed publisher

Agerholm M, Dall M, Jensen B, Prats C, Madsen S, Basse A, et al. Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle. Am J Physiol Endocrinol Metab. 2018;314:E377-E395 pubmed publisher

Kang Y, Stroud D, Baker M, De Souza D, Frazier A, Liem M, et al. Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex. Mol Cell. 2017;67:457-470.e5 pubmed publisher

Li M, Tan I, Ma S, Hockings C, Kratina T, Dengler M, et al. BAK ?6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove. Proc Natl Acad Sci U S A. 2017;114:7629-7634 pubmed publisher

Kuchay S, Giorgi C, Simoneschi D, Pagan J, Missiroli S, Saraf A, et al. PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth. Nature. 2017;546:554-558 pubmed publisher

Zhang P, Zheng Z, Ling L, Yang X, Zhang N, Wang X, et al. w09, a novel autophagy enhancer, induces autophagy-dependent cell apoptosis via activation of the EGFR-mediated RAS-RAF1-MAP2K-MAPK1/3 pathway. Autophagy. 2017;13:1093-1112 pubmed publisher

Uren R, O Hely M, Iyer S, Bartolo R, Shi M, Brouwer J, et al. Disordered clusters of Bak dimers rupture mitochondria during apoptosis. elife. 2017;6: pubmed publisher

Prenek L, Boldizsár F, Kugyelka R, Ugor E, Berta G, Németh P, et al. The regulation of the mitochondrial apoptotic pathway by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cells. Apoptosis. 2017;22:239-253 pubmed publisher

Mahapatra G, Varughese A, Ji Q, Lee I, Liu J, Vaishnav A, et al. Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney: IMPLICATIONS FOR AMP KINASE. J Biol Chem. 2017;292:64-79 pubmed publisher

Woo S, Min K, Seo B, Kwon T. YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-?B-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells. Oncotarget. 2016;7:61520-61532 pubmed publisher

Yamaguchi R, Harada H, Hirota K. VHL-deficient renal cancer cells gain resistance to mitochondria-activating apoptosis inducers by activating AKT through the IGF1R-PI3K pathway. Tumour Biol. 2016;37:13295-13306 pubmed

Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, et al. A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway. Mol Cell. 2016;63:229-239 pubmed publisher

Iyer S, Anwari K, Alsop A, Yuen W, Huang D, Carroll J, et al. Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies. Nat Commun. 2016;7:11734 pubmed publisher

Hattori K, Naguro I, Okabe K, Funatsu T, Furutani S, Takeda K, et al. ASK1 signalling regulates brown and beige adipocyte function. Nat Commun. 2016;7:11158 pubmed publisher

Chen H, Kanai M, Inoue Yamauchi A, Tu H, Huang Y, Ren D, et al. An interconnected hierarchical model of cell death regulation by the BCL-2 family. Nat Cell Biol. 2015;17:1270-81 pubmed publisher

Gibson G, Xu H, Chen H, Chen W, Denton T, Zhang S. Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines. J Neurochem. 2015;134:86-96 pubmed publisher

Fang L, Hemion C, Pinho Ferreira Bento A, Bippes C, Flammer J, Neutzner A. Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control. Front Cell Neurosci. 2015;9:16 pubmed publisher

Cavallucci V, Bisicchia E, Cencioni M, Ferri A, Latini L, Nobili A, et al. Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons. Cell Death Dis. 2014;5:e1545 pubmed publisher

Cao Y, Rathmell J, Macintyre A. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS ONE. 2014;9:e104104 pubmed publisher

Endo H, Yano M, Okumura Y, Kido H. Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70. Cell Death Dis. 2014;5:e1027 pubmed publisher

Quast S, Berger A, Eberle J. ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis. Cell Death Dis. 2013;4:e839 pubmed publisher

Yehuda Shnaidman E, Nimri L, Tarnovscki T, Kirshtein B, Rudich A, Schwartz B. Secreted human adipose leptin decreases mitochondrial respiration in HCT116 colon cancer cells. PLoS ONE. 2013;8:e74843 pubmed publisher

Simone L, Caplan S, Naslavsky N. Role of phosphatidylinositol 4,5-bisphosphate in regulating EHD2 plasma membrane localization. PLoS ONE. 2013;8:e74519 pubmed publisher

Murata H, Sakaguchi M, Kataoka K, Huh N. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell. 2013;24:2772-84 pubmed publisher

Abadi A, Crane J, Ogborn D, Hettinga B, Akhtar M, Stokl A, et al. Supplementation with ?-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice. PLoS ONE. 2013;8:e60722 pubmed publisher

Berger A, Quast S, Plötz M, Kammermeier A, Eberle J. Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax. Cell Death Dis. 2013;4:e477 pubmed publisher

Stolpmann K, Brinkmann J, Salzmann S, Genkinger D, Fritsche E, Hutzler C, et al. Activation of the aryl hydrocarbon receptor sensitises human keratinocytes for CD95L- and TRAIL-induced apoptosis. Cell Death Dis. 2012;3:e388 pubmed publisher

Hu J, Yao H, Gan F, Tokarski A, Wang Y. Interaction of OKL38 and p53 in regulating mitochondrial structure and function. PLoS ONE. 2012;7:e43362 pubmed publisher

Wu G, Jiang M, Liu Y, Nagaoka Y, Rao N. Phenotype of transgenic mice overexpressed with inducible nitric oxide synthase in the retina. PLoS ONE. 2012;7:e43089 pubmed publisher

Ofengeim D, Chen Y, Miyawaki T, Li H, Sacchetti S, Flannery R, et al. N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death. Nat Neurosci. 2012;15:574-80 pubmed publisher

de Pablo Latorre R, Saide A, Polishhuck E, Nusco E, Fraldi A, Ballabio A. Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases. Hum Mol Genet. 2012;21:1770-81 pubmed publisher

Yamaguchi R, Janssen E, Perkins G, Ellisman M, Kitada S, Reed J. Efficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapy. PLoS ONE. 2011;6:e24102 pubmed publisher

Kaur J, Mencl S, Sahaboglu A, Farinelli P, van Veen T, Zrenner E, et al. Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. PLoS ONE. 2011;6:e22181 pubmed publisher

Mahmoudi S, Henriksson S, Farnebo L, Roberg K, Farnebo M. WRAP53 promotes cancer cell survival and is a potential target for cancer therapy. Cell Death Dis. 2011;2:e114 pubmed publisher

Zhang H, Gogada R, Yadav N, Lella R, Badeaux M, Ayres M, et al. Defective molecular timer in the absence of nucleotides leads to inefficient caspase activation. PLoS ONE. 2011;6:e16379 pubmed publisher

Liu F, Hu X, Zimmerman M, Waller J, Wu P, Hayes Jordan A, et al. TNF? cooperates with IFN-? to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis. PLoS ONE. 2011;6:e16241 pubmed publisher

Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol. 2010;8:e1000410 pubmed publisher

Ma L, Buchold G, Greenbaum M, Roy A, Burns K, Zhu H, et al. GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet. 2009;5:e1000635 pubmed publisher

Rardin M, Wiley S, Murphy A, Pagliarini D, Dixon J. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem. 2008;283:15440-50 pubmed publisher

Lee E, Czabotar P, van Delft M, Michalak E, Boyle M, Willis S, et al. A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation. J Cell Biol. 2008;180:341-55 pubmed publisher

Gillissen B, Essmann F, Hemmati P, Richter A, Richter A, Oztop I, et al. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis. J Cell Biol. 2007;179:701-15 pubmed

Margineantu D, Emerson C, Diaz D, Hockenbery D. Hsp90 inhibition decreases mitochondrial protein turnover. PLoS ONE. 2007;2:e1066 pubmed

Zhu C, Wang X, Deinum J, Huang Z, Gao J, Modjtahedi N, et al. Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia. J Exp Med. 2007;204:1741-8 pubmed

Uren R, Dewson G, Chen L, Coyne S, Huang D, Adams J, et al. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak. J Cell Biol. 2007;177:277-87 pubmed

Niemann A, Ruegg M, La Padula V, Schenone A, Suter U. Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J Cell Biol. 2005;170:1067-78 pubmed

Dorstyn L, Mills K, Lazebnik Y, Kumar S. The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells. J Cell Biol. 2004;167:405-10 pubmed

Rehm M, Dussmann H, Prehn J. Real-time single cell analysis of Smac/DIABLO release during apoptosis. J Cell Biol. 2003;162:1031-43 pubmed

Clarke M, Savill J, Jones D, Noble B, Brown S. Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death. J Cell Biol. 2003;160:577-87 pubmed

Ricci J, Gottlieb R, Green D. Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis. J Cell Biol. 2003;160:65-75 pubmed

Arnoult D, Parone P, Martinou J, Antonsson B, Estaquier J, Ameisen J. Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli. J Cell Biol. 2002;159:923-9 pubmed

Malisan F, Franchi L, Tomassini B, Ventura N, Condo I, Rippo M, et al. Acetylation suppresses the proapoptotic activity of GD3 ganglioside. J Exp Med. 2002;196:1535-41 pubmed

Schwer B, North B, Frye R, Ott M, Verdin E. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol. 2002;158:647-57 pubmed

Dorstyn L, Read S, Cakouros D, Huh J, Hay B, Kumar S. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. J Cell Biol. 2002;156:1089-98 pubmed

Zimmermann K, Ricci J, Droin N, Green D. The role of ARK in stress-induced apoptosis in Drosophila cells. J Cell Biol. 2002;156:1077-87 pubmed

Dijkers P, Birkenkamp K, Lam E, Thomas N, Lammers J, Koenderman L, et al. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J Cell Biol. 2002;156:531-42 pubmed

Madesh M, Hajnoczky G. VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release. J Cell Biol. 2001;155:1003-15 pubmed

Waterhouse N, Goldstein J, von Ahsen O, Schuler M, Newmeyer D, Green D. Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J Cell Biol. 2001;153:319-28 pubmed

Jacotot E, Ferri K, El Hamel C, Brenner C, Druillennec S, Hoebeke J, et al. Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2. J Exp Med. 2001;193:509-19 pubmed

Heibein J, Goping I, Barry M, Pinkoski M, Shore G, Green D, et al. Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax. J Exp Med. 2000;192:1391-402 pubmed

Zhou H, Li X, Meinkoth J, Pittman R. Akt regulates cell survival and apoptosis at a postmitochondrial level. J Cell Biol. 2000;151:483-94 pubmed

von Ahsen O, Renken C, Perkins G, Kluck R, Bossy Wetzel E, Newmeyer D. Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release. J Cell Biol. 2000;150:1027-36 pubmed

Nakamura K, Bossy Wetzel E, Burns K, Fadel M, Lozyk M, Goping I, et al. Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis. J Cell Biol. 2000;150:731-40 pubmed

Latta M, Künstle G, Leist M, Wendel A. Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis. J Exp Med. 2000;191:1975-85 pubmed

Jacotot E, Ravagnan L, Loeffler M, Ferri K, Vieira H, Zamzami N, et al. The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J Exp Med. 2000;191:33-46 pubmed