Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:1000; loading ...; fig 6f
| Gao X, Chen H, Liu J, Shen S, Wang Q, Clement T, et al. The REGγ-Proteasome Regulates Spermatogenesis Partially by P53-PLZF Signaling. Stem Cell Reports. 2019;13:559-571 pubmed publisher
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- western blot; mouse; loading ...; fig 3e
| Zhao Y, Tan M, Liu X, Xiong X, Sun Y. Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes. Cell Death Dis. 2018;9:145 pubmed publisher
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- western blot; human; loading ...; fig 6
| Lee T, Pelletier J. Dependence of p53-deficient cells on the DHX9 DExH-box helicase. Oncotarget. 2017;8:30908-30921 pubmed publisher
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- western blot; human; loading ...; fig 6a
| Yuan H, Tan B, Gao S. Tenovin-6 impairs autophagy by inhibiting autophagic flux. Cell Death Dis. 2017;8:e2608 pubmed publisher
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- immunohistochemistry; mouse; 1:1000; loading ...; fig 7h
- western blot; human; 1:2000; loading ...; fig 3g
| Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, et al. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017;8:14002 pubmed publisher
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- western blot; human; 1:500; loading ...; fig 6,7d
| Marquez Vilendrer S, Thompson K, Lu L, Reisman D. Mechanism of BRG1 silencing in primary cancers. Oncotarget. 2016;7:56153-56169 pubmed publisher
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- western blot; human; fig 1
| Hampp S, Kiessling T, Buechle K, Mansilla S, Thomale J, Rall M, et al. DNA damage tolerance pathway involving DNA polymerase ? and the tumor suppressor p53 regulates DNA replication fork progression. Proc Natl Acad Sci U S A. 2016;113:E4311-9 pubmed publisher
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- western blot; mouse; fig 3
| Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed publisher
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- western blot; mouse; fig 3
| He D, Xiang J, Li B, Liu H. The dynamic behavior of Ect2 in response to DNA damage. Sci Rep. 2016;6:24504 pubmed publisher
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- western blot; human; fig 3a
| Garcia C, Videla Richardson G, Dimopoulos N, Fernandez Espinosa D, Miriuka S, Sevlever G, et al. Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. PLoS ONE. 2016;11:e0152607 pubmed publisher
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- western blot; mouse; fig s1
| Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed publisher
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- western blot; human; loading ...; fig 4e
| Niopek D, Wehler P, Roensch J, Eils R, Di Ventura B. Optogenetic control of nuclear protein export. Nat Commun. 2016;7:10624 pubmed publisher
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- other; human; loading ...; fig st1
| Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
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- western blot; human; fig 2
| Marazita M, Dugour A, Marquioni Ramella M, Figueroa J, Suburo A. Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration. Redox Biol. 2016;7:78-87 pubmed publisher
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- western blot; human; 1:1000; fig 4b
| Hu D, Gur M, Zhou Z, Gamper A, Hung M, Fujita N, et al. Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis. Nat Commun. 2015;6:8419 pubmed publisher
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- western blot; human; fig 11
| Daou S, Hammond Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono N, et al. The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem. 2015;290:28643-63 pubmed publisher
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- western blot; mouse; fig s3
| Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher
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- western blot; mouse; 1:2000; fig 3
| Cheedipudi S, Puri D, Saleh A, Gala H, Rumman M, Pillai M, et al. A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene. Nucleic Acids Res. 2015;43:6236-56 pubmed publisher
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| Yamauchi T, Nishiyama M, Moroishi T, Yumimoto K, Nakayama K. MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24. Mol Cell Biol. 2014;34:3321-40 pubmed publisher
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- western blot; human; fig 2
| Hayashi A, Suenaga N, Shiomi Y, Nishitani H. PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells. Methods Mol Biol. 2014;1170:367-82 pubmed publisher
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- western blot; rat; 1:1000
| Borkham Kamphorst E, Schaffrath C, Van De Leur E, Haas U, Tihaa L, Meurer S, et al. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-? signaling. Biochim Biophys Acta. 2014;1843:902-14 pubmed publisher
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| Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed publisher
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| Kaur A, Lim J, Sepramaniam S, Patnaik S, Harmston N, Lee M, et al. WNT inhibition creates a BRCA-like state in Wnt-addicted cancer. EMBO Mol Med. 2021;13:e13349 pubmed publisher
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| Crochemore C, Fernandez Molina C, Montagne B, Salles A, Ricchetti M. CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence. Nat Commun. 2019;10:5576 pubmed publisher
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| Zhou Z, Feng Z, Hu D, Yang P, Gur M, Bahar I, et al. A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy. EBioMedicine. 2019;: pubmed publisher
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| Aubrecht T, Faden A, Sabirzhanov B, Glaser E, Roelofs B, Polster B, et al. Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury. Cell Death Dis. 2018;9:1121 pubmed publisher
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| Osei Kuffour E, Schott K, Jaguva Vasudevan A, Holler J, Schulz W, Lang P, et al. USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1. J Virol. 2018;92: pubmed publisher
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| Peters D, Radine C, Reese A, Budach W, Sohn D, Janicke R. The DEAD-box RNA helicase DDX41 is a novel repressor of p21WAF1/CIP1 mRNA translation. J Biol Chem. 2017;292:8331-8341 pubmed publisher
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| Ge X, Chen S, Liu M, Liang T, Liu C. Evodiamine inhibits PDGF?BB?induced proliferation of rat vascular smooth muscle cells through the suppression of cell cycle progression and oxidative stress. Mol Med Rep. 2016;14:4551-4558 pubmed publisher
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| Beer A, Zenzmaier C, Schreinlechner M, Haas J, Dietrich M, Herz J, et al. Expression of a recombinant full-length LRP1B receptor in human non-small cell lung cancer cells confirms the postulated growth-suppressing function of this large LDL receptor family member. Oncotarget. 2016;7:68721-68733 pubmed publisher
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| Menendez D, Lowe J, Snipe J, Resnick M. Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells. Oncotarget. 2016;7:61630-61642 pubmed publisher
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| Gu Y, Bouwman P, Greco D, Saarela J, Yadav B, Jonkers J, et al. Suppression of BRCA1 sensitizes cells to proteasome inhibitors. Cell Death Dis. 2014;5:e1580 pubmed publisher
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| Lim H, Xie L, Zhang W, Li R, Chen Z, Wu G, et al. Ribosomal S6 Kinase 2 (RSK2) maintains genomic stability by activating the Atm/p53-dependent DNA damage pathway. PLoS ONE. 2013;8:e74334 pubmed publisher
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| Greussing R, Hackl M, Charoentong P, Pauck A, Monteforte R, Cavinato M, et al. Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics. 2013;14:224 pubmed publisher
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| Ma P, Schultz R. Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse. PLoS Genet. 2013;9:e1003377 pubmed publisher
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| Yehezkel S, Shaked R, Sagie S, Berkovitz R, Shachar Bener H, Segev Y, et al. Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts. Front Oncol. 2013;3:35 pubmed publisher
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| Yang Y, Durando M, Smith Roe S, Sproul C, Greenwalt A, Kaufmann W, et al. Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage. Nucleic Acids Res. 2013;41:2296-312 pubmed publisher
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| Mackenzie Ross A, Cook M, Chong H, Hossain M, Pandha H, Bennett D. Senescence evasion in melanoma progression: uncoupling of DNA-damage signaling from p53 activation and p21 expression. Pigment Cell Melanoma Res. 2013;26:226-35 pubmed publisher
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| Korfali N, Srsen V, Waterfall M, Batrakou D, Pekovic V, Hutchison C, et al. A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal. PLoS ONE. 2011;6:e18762 pubmed publisher
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| Vilas Zornoza A, Agirre X, Martín Palanco V, Martin Subero J, San Jose Eneriz E, Garate L, et al. Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia. PLoS ONE. 2011;6:e17012 pubmed publisher
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