product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
PMS2
catalog :
556415
quantity :
0.1 mg
price :
270.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A16-4
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:500; loading ...; fig 4a
Fischer J, Dudley S, Miller A, Liskay R. An intact Pms2 ATPase domain is not essential for male fertility. DNA Repair (Amst). 2016;39:46-51 pubmed publisher
  • western blot; human; 1:2500; loading ...; fig 4a
Abildgaard A, Stein A, Nielsen S, Schultz Knudsen K, Papaleo E, Shrikhande A, et al. Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome. elife. 2019;8: pubmed publisher
  • immunohistochemistry; human; 1:100; fig s4b
Beltran H, Prandi D, Mosquera J, Benelli M, Puca L, Cyrta J, et al. Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016;22:298-305 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...
Taieb J, Zaanan A, Le Malicot K, Julie C, Blons H, Mineur L, et al. Prognostic Effect of BRAF and KRAS Mutations in Patients With Stage III Colon Cancer Treated With Leucovorin, Fluorouracil, and Oxaliplatin With or Without Cetuximab: A Post Hoc Analysis of the PETACC-8 Trial. JAMA Oncol. 2016;2:643-653 pubmed publisher
  • immunohistochemistry; human; 1:100
Vanoli A, Argenti F, Vinci A, La Rosa S, Viglio A, Riboni R, et al. Hepatoid carcinoma of the pancreas with lymphoid stroma: first description of the clinical, morphological, immunohistochemical, and molecular characteristics of an unusual pancreatic carcinoma. Virchows Arch. 2015;467:237-45 pubmed publisher
  • immunohistochemistry; human; 1:100
Geels Y, van der Putten L, van Tilborg A, Lurkin I, Zwarthoff E, Pijnenborg J, et al. Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium. Gynecol Oncol. 2015;137:245-51 pubmed publisher
  • immunohistochemistry - paraffin section; human
Vilar E, Mork M, Cuddy A, Borràs E, Bannon S, Taggart M, et al. Role of microsatellite instability-low as a diagnostic biomarker of Lynch syndrome in colorectal cancer. Cancer Genet. 2014;207:495-502 pubmed publisher
  • western blot; human
Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300
Koppensteiner R, Samartzis E, Noske A, von Teichman A, Dedes I, Gwerder M, et al. Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro. PLoS ONE. 2014;9:e100041 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Egoavil C, Alenda C, Castillejo A, Paya A, Peiro G, Sanchez Heras A, et al. Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers. PLoS ONE. 2013;8:e79737 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Schroering A, Williams K. Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment. DNA Repair (Amst). 2008;7:951-69 pubmed publisher
Knudsen K, Nielsen B, Lindebjerg J, Hansen T, Holst R, Sørensen F. microRNA-17 Is the Most Up-Regulated Member of the miR-17-92 Cluster during Early Colon Cancer Evolution. PLoS ONE. 2015;10:e0140503 pubmed publisher
Vlenterie M, Hillebrandt Roeffen M, Flucke U, Groenen P, Tops B, Kamping E, et al. Next generation sequencing in synovial sarcoma reveals novel gene mutations. Oncotarget. 2015;6:34680-90 pubmed publisher
Seppälä T, Böhm J, Friman M, Lahtinen L, Väyrynen V, Liipo T, et al. Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer. Br J Cancer. 2015;112:1966-75 pubmed publisher
Grigera F, Bellacosa A, Kenter A. Complex relationship between mismatch repair proteins and MBD4 during immunoglobulin class switch recombination. PLoS ONE. 2013;8:e78370 pubmed publisher
van Grieken N, Aoyama T, Aoyma T, Chambers P, Bottomley D, Ward L, et al. KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: results from a large international multicentre study. Br J Cancer. 2013;108:1495-501 pubmed publisher
Wangefjord S, Brändstedt J, Lindquist K, Nodin B, Jirstrom K, Eberhard J. Associations of beta-catenin alterations and MSI screening status with expression of key cell cycle regulating proteins and survival from colorectal cancer. Diagn Pathol. 2013;8:10 pubmed publisher
von Bueren A, Bacolod M, Hagel C, Heinimann K, Fedier A, Kordes U, et al. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. Br J Cancer. 2012;107:1399-408 pubmed publisher
Ottenhof N, Morsink F, Ten Kate F, Van Noorden C, Offerhaus G. Multivariate analysis of immunohistochemical evaluation of protein expression in pancreatic ductal adenocarcinoma reveals prognostic significance for persistent Smad4 expression only. Cell Oncol (Dordr). 2012;35:119-26 pubmed publisher
Eberhard J, Gaber A, Wangefjord S, Nodin B, Uhlen M, Ericson Lindquist K, et al. A cohort study of the prognostic and treatment predictive value of SATB2 expression in colorectal cancer. Br J Cancer. 2012;106:931-8 pubmed publisher
van der Post R, Kiemeney L, Ligtenberg M, Witjes J, Hulsbergen van de Kaa C, Bodmer D, et al. Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers. J Med Genet. 2010;47:464-70 pubmed publisher
Overbeek L, Kets C, Hebeda K, Bodmer D, van der Looij E, Willems R, et al. Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer. Br J Cancer. 2007;96:1605-12 pubmed
Kets C, van Krieken J, Hebeda K, Wezenberg S, Goossens M, Brunner H, et al. Very low prevalence of germline MSH6 mutations in hereditary non-polyposis colorectal cancer suspected patients with colorectal cancer without microsatellite instability. Br J Cancer. 2006;95:1678-82 pubmed
product information
Cat.# :
556415
Brand :
BD Pharmingen
Name :
PMS2
Format :
Purified
Clone :
A16-4
Isotype :
Ms IgG 1
React :
Hu , Ms
Conc :
0.5 mg/ml
Apps :
WB
Size :
0.1 mg
Status :
RUO
List Price :
270.00 USD
more info or order :
company information