product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
PARP
catalog :
556362
quantity :
0.1 mL
price :
295.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C2-10
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 33
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3c
Leslie P, Franklin D, Liu Y, Zhang Y. p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback Loop. Cell Rep. 2018;24:1484-1495 pubmed publisher
  • western blot; mouse; loading ...; fig 1c
  • western blot; human; loading ...; fig 1f
Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig s5a
Williams P, Harder J, Foxworth N, Cochran K, Philip V, Porciatti V, et al. Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science. 2017;355:756-760 pubmed publisher
  • western blot; human; loading ...; fig 1a
Duclos C, Champagne A, Carrier J, Saucier C, Lavoie C, Denault J. Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling. Cell Death Discov. 2017;3:16100 pubmed publisher
  • western blot; human; loading ...; fig 1c
Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed publisher
  • western blot; human; loading ...; fig 1f
Itahana Y, Zhang J, Göke J, Vardy L, Han R, Iwamoto K, et al. Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. Sci Rep. 2016;6:28112 pubmed publisher
  • western blot; mouse; fig 6
Rebolleda N, Losada Fernandez I, Perez Chacon G, Castejon R, Rosado S, Morado M, et al. Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. PLoS ONE. 2016;11:e0154159 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 4c
Rasmussen R, Gajjar M, Jensen K, Hamerlik P. Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma. Mol Oncol. 2016;10:751-63 pubmed publisher
  • western blot; human; fig 5
Phillips D, Xiao Y, Lam L, Litvinovich E, Roberts Rapp L, Souers A, et al. Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199). Blood Cancer J. 2015;5:e368 pubmed publisher
  • western blot; human; fig 2
Ambroise G, Portier A, Roders N, Arnoult D, Vazquez A. Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells. Oncotarget. 2015;6:38181-94 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human
Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed publisher
  • western blot; human
Wang X, Stafford W, Mazurkiewicz M, Fryknäs M, Brjnic S, Zhang X, et al. The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death. Mol Pharmacol. 2014;85:932-45 pubmed publisher
  • western blot; human; fig 5
Wan F, Weaver A, Gao X, Bern M, Hardwidge P, Lenardo M. IKK? phosphorylation regulates RPS3 nuclear translocation and NF-?B function during infection with Escherichia coli strain O157:H7. Nat Immunol. 2011;12:335-43 pubmed publisher
  • western blot; human
Schroering A, Williams K. Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment. DNA Repair (Amst). 2008;7:951-69 pubmed publisher
Baraz R, Cisterne A, Saunders P, Hewson J, Thien M, Weiss J, et al. mTOR inhibition by everolimus in childhood acute lymphoblastic leukemia induces caspase-independent cell death. PLoS ONE. 2014;9:e102494 pubmed publisher
Vijayalingam S, Kuppusamy M, Subramanian T, Strebeck F, West C, Varvares M, et al. Evaluation of apoptogenic adenovirus type 5 oncolytic vectors in a Syrian hamster head and neck cancer model. Cancer Gene Ther. 2014;21:228-237 pubmed publisher
Licht V, Noack K, Schlott B, Forster M, Schlenker Y, Licht A, et al. Caspase-3 and caspase-6 cleave STAT1 in leukemic cells. Oncotarget. 2014;5:2305-17 pubmed
Zheng X, Ding N, Song Y, Feng L, Zhu J. Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment. Cancer Cell Int. 2014;14:32 pubmed publisher
Reddy M, Akula B, Cosenza S, Athuluridivakar S, Mallireddigari M, Pallela V, et al. Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5). J Med Chem. 2014;57:578-99 pubmed publisher
Weissinger D, Tagscherer K, Macher Göppinger S, Haferkamp A, Wagener N, Roth W. The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma. Mol Cancer. 2013;12:120 pubmed publisher
Sosna J, Voigt S, Mathieu S, Lange A, Thon L, Davarnia P, et al. TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci. 2014;71:331-48 pubmed publisher
Smith M, Ferguson J, Arozarena I, Hayward R, Marais R, Chapman A, et al. Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma. J Natl Cancer Inst. 2013;105:33-46 pubmed publisher
Orr S, Boutz D, Wang R, Chronis C, Lea N, Thayaparan T, et al. Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry. Mol Syst Biol. 2012;8:573 pubmed publisher
van Vuurden D, Hulleman E, Meijer O, Wedekind L, Kool M, Witt H, et al. PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation. Oncotarget. 2011;2:984-96 pubmed
Kaur J, Mencl S, Sahaboglu A, Farinelli P, van Veen T, Zrenner E, et al. Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. PLoS ONE. 2011;6:e22181 pubmed publisher
McConnell B, Koto K, Gutierrez Hartmann A. Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression. Mol Cancer. 2011;10:75 pubmed publisher
Mahmoudi S, Henriksson S, Farnebo L, Roberg K, Farnebo M. WRAP53 promotes cancer cell survival and is a potential target for cancer therapy. Cell Death Dis. 2011;2:e114 pubmed publisher
Ho J, Asagiri M, Hoffmann A, Ghosh G. NF-?B potentiates caspase independent hydrogen peroxide induced cell death. PLoS ONE. 2011;6:e16815 pubmed publisher
Chaussepied M, Janski N, Baumgartner M, Lizundia R, Jensen K, Weir W, et al. TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility. PLoS Pathog. 2010;6:e1001197 pubmed publisher
Sahaboglu A, Tanimoto N, Kaur J, Sancho Pelluz J, Huber G, Fahl E, et al. PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function. PLoS ONE. 2010;5:e15495 pubmed publisher
Walters J, Pop C, Scott F, Drag M, Swartz P, Mattos C, et al. A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis. Biochem J. 2009;424:335-45 pubmed publisher
Montes De Oca R, Shoemaker C, Gucek M, Cole R, Wilson K. Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners. PLoS ONE. 2009;4:e7050 pubmed publisher
Matthews J, Watson S, Tevendale M, Watson C, Clarke A. Caspase-dependent proteolytic cleavage of STAT3alpha in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines. BMC Cancer. 2007;7:29 pubmed
product information
Cat.# :
556362
Brand :
BD Pharmingen
Name :
PARP
Format :
Ascites
Clone :
C2-10
Isotype :
Ms IgG 1
React :
Hu
Apps :
WB
Size :
0.1 mL
Status :
RUO
List Price :
295.00 USD
more info or order :
company information