Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; 1:1000; loading ...; fig 1a
| Mathieu M, Nevo N, Jouve M, Valenzuela J, Maurin M, Verweij F, et al. Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9. Nat Commun. 2021;12:4389 pubmed publisher
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- western blot; human; 1:500; loading ...; fig s10d
| Claude Taupin A, Jia J, Bhujabal Z, Garfa Traoré M, Kumar S, da Silva G, et al. ATG9A protects the plasma membrane from programmed and incidental permeabilization. Nat Cell Biol. 2021;23:846-858 pubmed publisher
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- immunohistochemistry - frozen section; human; fig 2d
| Wu A, Sung Y, Chen Y, Chou S, Guo V, Chien J, et al. Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism. Adv Sci (Weinh). 2020;7:2001467 pubmed publisher
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- flow cytometry; human; 1:20; loading ...; fig s4a, s4b
- western blot; human; 1:1000; loading ...; fig 5f
| Crescitelli R, Lässer C, Jang S, Cvjetkovic A, Malmhäll C, Karimi N, et al. Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation. J Extracell Vesicles. 2020;9:1722433 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 7a
- western blot; human; loading ...; fig 1b, 3d, 3c 4h
| Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
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- western blot; human; loading ...; fig 2f
| Lee J, Dindorf J, Eberhardt M, Lai X, Ostalecki C, Koliha N, et al. Innate extracellular vesicles from melanoma patients suppress β-catenin in tumor cells by miRNA-34a. Life Sci Alliance. 2019;2: pubmed publisher
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- immunohistochemistry; human; loading ...; fig 3a
- western blot; human; loading ...; fig 1c
| Messenger S, Woo S, Sun Z, Martin T. A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4. J Cell Biol. 2018;217:2877-2890 pubmed publisher
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- western blot; human; loading ...; fig 6f
| Verweij F, Bebelman M, Jimenez C, Garcia Vallejo J, Janssen H, Neefjes J, et al. Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling. J Cell Biol. 2018;217:1129-1142 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 1b
- western blot; human; loading ...; fig 1a
| Earnest J, Hantak M, Li K, McCray P, Perlman S, Gallagher T. The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. PLoS Pathog. 2017;13:e1006546 pubmed publisher
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- western blot; human; 1:500; fig 5c
| Jong A, Wu C, Li J, Sun J, Fabbri M, Wayne A, et al. Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells. J Extracell Vesicles. 2017;6:1294368 pubmed publisher
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- immunocytochemistry; human; 1:2000; loading ...; fig 6a
| Roy N, Pacini G, Berlioz Torrent C, Janvier K. Characterization of E3 ligases involved in lysosomal sorting of the HIV-1 restriction factor BST2. J Cell Sci. 2017;130:1596-1611 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 5a
| Larson C, Heinzen R. High-Content Imaging Reveals Expansion of the Endosomal Compartment during Coxiella burnetii Parasitophorous Vacuole Maturation. Front Cell Infect Microbiol. 2017;7:48 pubmed publisher
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- immunocytochemistry; African green monkey; loading ...; fig s2
| McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed publisher
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- immunocytochemistry; human; fig 1
| Justis A, Hansen B, Beare P, King K, Heinzen R, Gilk S. Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L. Cell Microbiol. 2017;19: pubmed publisher
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- western blot; brewer's yeast; 1:1000; fig s4
| Andersson A, Andersson B, Lorell C, Raffetseder J, Larsson M, Blomgran R. Autophagy induction targeting mTORC1 enhances Mycobacterium tuberculosis replication in HIV co-infected human macrophages. Sci Rep. 2016;6:28171 pubmed publisher
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- western blot; human; 1:1000; fig 2
| Wäster P, Eriksson I, Vainikka L, Rosdahl I, Ollinger K. Extracellular vesicles are transferred from melanocytes to keratinocytes after UVA irradiation. Sci Rep. 2016;6:27890 pubmed publisher
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- immunocytochemistry; human; fig 4
| Rapiteanu R, Davis L, Williamson J, Timms R, Paul Luzio J, Lehner P. A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin. Traffic. 2016;17:940-58 pubmed publisher
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- other; human; 500 ug/ml; fig 1
| Belov L, Matic K, Hallal S, Best O, Mulligan S, Christopherson R. Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples. J Extracell Vesicles. 2016;5:25355 pubmed publisher
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- flow cytometry; human; 10 ug/ml; fig 3
| Khazen R, Müller S, Gaudenzio N, Espinosa E, Puissegur M, Valitutti S. Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse. Nat Commun. 2016;7:10823 pubmed publisher
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- western blot; human; fig 2
| Kowal J, Arras G, Colombo M, Jouve M, Morath J, Primdal Bengtson B, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A. 2016;113:E968-77 pubmed publisher
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- immunocytochemistry; human; fig 1
| Majumder P, Chakrabarti O. Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101. Cell Death Dis. 2015;6:e1970 pubmed publisher
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- flow cytometry; mouse; fig s1a
| Phinney D, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix C, et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun. 2015;6:8472 pubmed publisher
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| Harshyne L, Nasca B, Kenyon L, Andrews D, Hooper D. Serum exosomes and cytokines promote a T-helper cell type 2 environment in the peripheral blood of glioblastoma patients. Neuro Oncol. 2016;18:206-15 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 6a
| Hirst J, Edgar J, Esteves T, Darios F, Madeo M, Chang J, et al. Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease. Hum Mol Genet. 2015;24:4984-96 pubmed publisher
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- immunoprecipitation; human; fig 2
| Shao H, Chung J, Lee K, Balaj L, Min C, Carter B, et al. Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nat Commun. 2015;6:6999 pubmed publisher
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- flow cytometry; human; fig 2
| Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, et al. Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens. Immunol Cell Biol. 2015;93:727-34 pubmed publisher
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- immunocytochemistry; human; 5 ug/ml
| Vallabhaneni K, Penfornis P, Dhule S, Guillonneau F, Adams K, Mo Y, et al. Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites. Oncotarget. 2015;6:4953-67 pubmed
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- immunocytochemistry; mouse
| Chivet M, Javalet C, Laulagnier K, Blot B, Hemming F, Sadoul R. Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons. J Extracell Vesicles. 2014;3:24722 pubmed publisher
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- western blot; human; 1:1000
| Lundholm M, Schröder M, Nagaeva O, Baranov V, Widmark A, Mincheva Nilsson L, et al. Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion. PLoS ONE. 2014;9:e108925 pubmed publisher
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- immunoprecipitation; human
- immunoprecipitation; mouse
| Shi M, Liu C, Cook T, Bullock K, Zhao Y, Ginghina C, et al. Plasma exosomal ?-synuclein is likely CNS-derived and increased in Parkinson's disease. Acta Neuropathol. 2014;128:639-650 pubmed publisher
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| Lozano Fernández T, Ballester Antxordoki L, Pérez Temprano N, Rojas E, Sanz D, Iglesias Gaspar M, et al. Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4. Nanomedicine. 2014;10:1301-10 pubmed publisher
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- western blot; human; 1:1000
| Armstrong A, Mattsson N, Appelqvist H, Janefjord C, Sandin L, Agholme L, et al. Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease. Neuromolecular Med. 2014;16:150-60 pubmed publisher
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- western blot; human; 1:150
| Camacho L, Guerrero P, Marchetti D. MicroRNA and protein profiling of brain metastasis competent cell-derived exosomes. PLoS ONE. 2013;8:e73790 pubmed publisher
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| Zhong L, Song Y, Marziali F, Uzbekov R, Nguyen X, Journo C, et al. A novel domain within the CIL regulates egress of IFITM3 from the Golgi and reveals a regulatory role of IFITM3 on the secretory pathway. Life Sci Alliance. 2022;5: pubmed publisher
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| Kamerkar S, LeBleu V, Sugimoto H, Yang S, Ruivo C, Melo S, et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017;546:498-503 pubmed publisher
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| Koliha N, Heider U, Ozimkowski T, Wiemann M, Bosio A, Wild S. Melanoma Affects the Composition of Blood Cell-Derived Extracellular Vesicles. Front Immunol. 2016;7:282 pubmed publisher
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| Zhu H, Guariglia S, Yu R, Li W, Brancho D, Peinado H, et al. Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes. Mol Biol Cell. 2013;24:1619-37, S1-3 pubmed publisher
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| Kosaka N, Iguchi H, Hagiwara K, Yoshioka Y, Takeshita F, Ochiya T. Neutral sphingomyelinase 2 (nSMase2)-dependent exosomal transfer of angiogenic microRNAs regulate cancer cell metastasis. J Biol Chem. 2013;288:10849-59 pubmed publisher
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