product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
IgM
catalog :
555780
quantity :
0.5 mg
price :
135.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G20-127
reactivity :
human, Rhesus monkey
application :
ELISA, flow cytometry, blocking or activating experiments, immunocytochemistry knockout validation
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; human; loading ...; fig 1f
He X, Kläsener K, Iype J, Becker M, Maity P, Cavallari M, et al. Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells. EMBO J. 2018;37: pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Sugimura R, Jha D, Han A, Soria Valles C, da Rocha E, Lu Y, et al. Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 2017;545:432-438 pubmed publisher
  • flow cytometry; human; loading ...; fig st1
Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. J Exp Med. 2017;214:1769-1785 pubmed publisher
  • flow cytometry; Rhesus monkey; loading ...; fig 3b
Stanfield B, Pahar B, Chouljenko V, Veazey R, Kousoulas K. Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies. Vaccine. 2017;35:536-543 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Keefer M, Zheng B, Rosenberg A, Kobie J. Increased Steady-State Memory B Cell Subsets Among High-Risk Participants in an HIV Vaccine Trial. AIDS Res Hum Retroviruses. 2016;32:1143-1148 pubmed
  • flow cytometry; human; loading ...; fig 2a
Piepenbrink M, Samuel M, Zheng B, Carter B, Fucile C, Bunce C, et al. Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users. PLoS ONE. 2016;11:e0158641 pubmed publisher
  • flow cytometry; human; loading ...
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • flow cytometry; human
Weber G, Chousterman B, Hilgendorf I, Robbins C, Theurl I, Gerhardt L, et al. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211:1243-56 pubmed publisher
  • flow cytometry; Rhesus monkey
Demberg T, Mohanram V, Venzon D, Robert Guroff M. Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model. Clin Immunol. 2014;153:264-76 pubmed publisher
  • flow cytometry; human
Barbosa R, Silva S, Silva S, Melo A, Pereira Santos M, Barata J, et al. Reduced BAFF-R and increased TACI expression in common variable immunodeficiency. J Clin Immunol. 2014;34:573-83 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 1a
Doi H, Tanoue S, Kaplan D. Peripheral CD27-CD21- B-cells represent an exhausted lymphocyte population in hepatitis C cirrhosis. Clin Immunol. 2014;150:184-91 pubmed publisher
Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, et al. Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell. 2019;178:567-584.e19 pubmed publisher
Heidt S, Vergunst M, Anholts J, Swings G, Gielis E, Groeneweg K, et al. Presence of intragraft B cells during acute renal allograft rejection is accompanied by changes in peripheral blood B cell subsets. Clin Exp Immunol. 2019;196:403-414 pubmed publisher
Embers M, Krishnavajhala A, Armstrong B, Curtis M, Pahar B, Wilder H, et al. Immunological Responses to the Relapsing Fever Spirochete Borrelia turicatae in Infected Rhesus Macaques: Implications for Pathogenesis and Diagnosis. Infect Immun. 2019;87: pubmed publisher
Boutboul D, Kuehn H, Van de Wyngaert Z, Niemela J, Callebaut I, Stoddard J, et al. Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. J Clin Invest. 2018;128:3071-3087 pubmed publisher
Manickam C, Nwanze C, Ram D, Shah S, Smith S, Jones R, et al. Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tract. AIDS. 2018;32:1571-1578 pubmed publisher
Liu Y, McDaniel J, Khan S, Campisi P, Propst E, Holler T, et al. Antibodies Encoded by FCRL4-Bearing Memory B Cells Preferentially Recognize Commensal Microbial Antigens. J Immunol. 2018;200:3962-3969 pubmed publisher
Wang L, Shi W, Chappell J, Joyce M, Zhang Y, Kanekiyo M, et al. Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J Virol. 2018;92: pubmed publisher
Bogaert D, Kuehn H, Bonroy C, Calvo K, Dehoorne J, Vanlander A, et al. A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects. J Allergy Clin Immunol. 2018;141:432-435.e7 pubmed publisher
Nakayama Y, Kosek J, Capone L, Hur E, Schafer P, Ringheim G. Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity. J Immunol. 2017;199:2388-2407 pubmed publisher
Das A, Xu H, Wang X, Yau C, Veazey R, Pahar B. Double-positive CD21+CD27+ B cells are highly proliferating memory cells and their distribution differs in mucosal and peripheral tissues. PLoS ONE. 2011;6:e16524 pubmed publisher
Kruetzmann S, Rosado M, Weber H, Germing U, Tournilhac O, Peter H, et al. Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med. 2003;197:939-45 pubmed
Chen X, Laur O, Kambayashi T, Li S, Bray R, Weber D, et al. Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development. J Exp Med. 2002;195:1053-62 pubmed
product information
Cat.# :
555780
Brand :
BD Pharmingen
Name :
IgM
Format :
Purified
Clone :
G20-127
Isotype :
Ms IgG 1
React :
Hu
Conc :
0.5 mg/ml
Apps :
ELISA , FCM
Size :
0.5 mg
Status :
RUO
List Price :
135.00 USD
more info or order :
company information