product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD81
catalog :
555675
quantity :
0.1 mg
price :
130.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JS-81
reactivity :
African green monkey, human, dog, Rhesus monkey
application :
western blot, immunocytochemistry, flow cytometry, proximity ligation assay, blocking or activating experiments, other, western blot knockout validation
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 1a, 1b
Earnest J, Hantak M, Li K, McCray P, Perlman S, Gallagher T. The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. PLoS Pathog. 2017;13:e1006546 pubmed publisher
  • flow cytometry; human; loading ...; tbl 2
Bzowska M, Nogieć A, Bania K, Zygmunt M, Zarebski M, Dobrucki J, et al. Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. J Leukoc Biol. 2017;102:763-774 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 3a
Lee M, Yang J, Jo E, Lee J, Kim H, Bartenschlager R, et al. A Novel Inhibitor IDPP Interferes with Entry and Egress of HCV by Targeting Glycoprotein E1 in a Genotype-Specific Manner. Sci Rep. 2017;7:44676 pubmed publisher
  • flow cytometry; human; fig 3c
Lisenko K, Schönland S, Hegenbart U, Wallenwein K, Braun U, Mai E, et al. Potential therapeutic targets in plasma cell disorders: A flow cytometry study. Cytometry B Clin Cytom. 2017;92:145-152 pubmed publisher
  • flow cytometry; human; fig 1d
Trautz B, Pierini V, Wombacher R, Stolp B, Chase A, Pizzato M, et al. The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor. J Virol. 2016;90:10915-10927 pubmed publisher
  • western blot; human; fig 2
Wong M, Chen S. Human Choline Kinase-? Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation. J Virol. 2016;90:9075-95 pubmed publisher
  • flow cytometry; human; 1 ug/ml; fig 1
  • western blot; human; fig 1
Shirasago Y, Shimizu Y, Tanida I, Suzuki T, Suzuki R, Sugiyama K, et al. Occludin-Knockout Human Hepatic Huh7.5.1-8-Derived Cells Are Completely Resistant to Hepatitis C Virus Infection. Biol Pharm Bull. 2016;39:839-48 pubmed publisher
  • flow cytometry; human; 1:200; fig 1
Nadeem A, Thomas P, Ulf M, Elena N, Anggakusuma A, Mohamed B, et al. Cell culture-derived HCV cannot infect synovial fibroblasts. Sci Rep. 2015;5:18043 pubmed publisher
  • blocking or activating experiments; human; fig 5
  • immunocytochemistry; human; fig 1
March S, Ramanan V, Trehan K, Ng S, Galstian A, Gural N, et al. Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens. Nat Protoc. 2015;10:2027-53 pubmed publisher
  • western blot; human; fig 6c
Santi A, Caselli A, Ranaldi F, Paoli P, Mugnaioni C, Michelucci E, et al. Cancer associated fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth. Biochim Biophys Acta. 2015;1853:3211-23 pubmed publisher
  • other; human; loading ...; fig e4c
Saeed M, Andreo U, Chung H, Espiritu C, Branch A, Silva J, et al. SEC14L2 enables pan-genotype HCV replication in cell culture. Nature. 2015;524:471-5 pubmed publisher
  • proximity ligation assay; human; loading ...; fig 13
  • immunocytochemistry; human; 1:50; loading ...; fig 2a
Le Q, Blanchet M, Seidah N, Labonté P. Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9. J Biol Chem. 2015;290:23385-400 pubmed publisher
  • immunocytochemistry; human; fig 10
Luo X, Fan Y, Park I, He J. Exosomes are unlikely involved in intercellular Nef transfer. PLoS ONE. 2015;10:e0124436 pubmed publisher
  • flow cytometry; human; fig s3d
  • western blot; human; 1:200; fig s1b
  • western blot; African green monkey; fig s1b
  • flow cytometry; Rhesus monkey; fig s3d
  • western blot; Rhesus monkey; fig s1b
Scull M, Shi C, De Jong Y, Gerold G, Ries M, von Schaewen M, et al. Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology. 2015;62:57-67 pubmed publisher
  • flow cytometry; human; fig 2
Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, et al. Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens. Immunol Cell Biol. 2015;93:727-34 pubmed publisher
  • flow cytometry; human
  • immunocytochemistry; human
  • western blot; human; fig 1
Lambelé M, Koppensteiner H, Symeonides M, Roy N, Chan J, Schindler M, et al. Vpu is the main determinant for tetraspanin downregulation in HIV-1-infected cells. J Virol. 2015;89:3247-55 pubmed publisher
  • flow cytometry; human; 1:500; loading ...; fig 6c
Shirasago Y, Sekizuka T, Saito K, Suzuki T, Wakita T, Hanada K, et al. Isolation and characterization of an Huh.7.5.1-derived cell clone highly permissive to hepatitis C virus. Jpn J Infect Dis. 2015;68:81-8 pubmed publisher
  • blocking or activating experiments; human
Bankwitz D, Vieyres G, Hueging K, Bitzegeio J, Doepke M, Chhatwal P, et al. Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins. J Virol. 2014;88:12644-55 pubmed publisher
  • flow cytometry; human; fig 1
Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, et al. Alternative endocytosis pathway for productive entry of hepatitis C virus. J Gen Virol. 2014;95:2658-67 pubmed publisher
  • blocking or activating experiments; human
Prentoe J, Serre S, Ramírez S, Nicosia A, Gottwein J, Bukh J. Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus. J Virol. 2014;88:1725-39 pubmed publisher
Kamerkar S, LeBleu V, Sugimoto H, Yang S, Ruivo C, Melo S, et al. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017;546:498-503 pubmed publisher
Velázquez Moctezuma R, Law M, Bukh J, Prentoe J. Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A. PLoS Pathog. 2017;13:e1006214 pubmed publisher
Li Q, Sodroski C, Lowey B, Schweitzer C, Cha H, Zhang F, et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2016;113:7620-5 pubmed publisher
Zuidscherwoude M, Göttfert F, Dunlock V, Figdor C, van den Bogaart G, van Spriel A. The tetraspanin web revisited by super-resolution microscopy. Sci Rep. 2015;5:12201 pubmed publisher
He J, Sun E, Bujny M, Kim D, Davidson M, Zhuang X. Dual function of CD81 in influenza virus uncoating and budding. PLoS Pathog. 2013;9:e1003701 pubmed publisher
Shaw M, Stone K, Colangelo C, Gulcicek E, Palese P. Cellular proteins in influenza virus particles. PLoS Pathog. 2008;4:e1000085 pubmed publisher
Bartosch B, Dubuisson J, Cosset F. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. J Exp Med. 2003;197:633-42 pubmed
Crotta S, Stilla A, Wack A, D ANDREA A, Nuti S, D Oro U, et al. Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein. J Exp Med. 2002;195:35-41 pubmed
product information
Cat.# :
555675
Brand :
BD Pharmingen
Name :
CD81
Format :
Purified
Clone :
JS-81
Isotype :
Ms IgG 1
React :
Hu , Dog , Rab
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.1 mg
Status :
RUO
List Price :
130.00 USD
more info or order :
company information