product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD3
catalog :
555337
quantity :
0.1 mg
price :
121.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HIT3a
reactivity :
human, mouse
application :
flow cytometry, blocking or activating experiments, other
more info or order :
citations: 52
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 5 ug/ml; loading ...; fig 1b
Yang T, St John L, Garber H, Kerros C, Ruisaard K, Clise Dwyer K, et al. Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation. J Immunol. 2018;201:1389-1399 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s13
Panda S, Facchinetti V, Voynova E, Hanabuchi S, Karnell J, Hanna R, et al. Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models. J Clin Invest. 2018;128:1873-1887 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Cerboni S, Jeremiah N, Gentili M, Gehrmann U, Conrad C, Stolzenberg M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes. J Exp Med. 2017;214:1769-1785 pubmed publisher
  • flow cytometry; human; loading ...; fig 3d
Su S, Zou Z, Chen F, Ding N, Du J, Shao J, et al. CRISPR-Cas9-mediated disruption of PD-1 on human T cells for adoptive cellular therapies of EBV positive gastric cancer. Oncoimmunology. 2017;6:e1249558 pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 2d
Raap U, Gehring M, Kleiner S, Rüdrich U, Eiz Vesper B, Haas H, et al. Human basophils are a source of - and are differentially activated by - IL-31. Clin Exp Allergy. 2017;47:499-508 pubmed publisher
  • flow cytometry; human; fig 1c
Chung B, Guevel B, Reynolds G, Gupta Udatha D, Henriksen E, Stamataki Z, et al. Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis. J Autoimmun. 2017;77:45-54 pubmed publisher
  • flow cytometry; human; loading ...; fig 3a
Ashizawa T, Iizuka A, Nonomura C, Kondou R, Maeda C, Miyata H, et al. Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse. Clin Cancer Res. 2017;23:149-158 pubmed publisher
  • flow cytometry; human; fig 5
Su S, Hu B, Shao J, Shen B, Du J, Du Y, et al. CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients. Sci Rep. 2016;6:20070 pubmed publisher
  • flow cytometry; human; loading ...; fig 2e
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed publisher
  • flow cytometry; human; fig 1a
Chen X, Li W, Zhang Y, Song X, Xu L, Xu Z, et al. Distribution of Peripheral Memory T Follicular Helper Cells in Patients with Schistosomiasis Japonica. PLoS Negl Trop Dis. 2015;9:e0004015 pubmed publisher
  • other; human; fig 2
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
  • flow cytometry; human; fig 1
Williams D, Anastos K, Morgello S, Berman J. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals. J Leukoc Biol. 2015;97:401-12 pubmed publisher
  • blocking or activating experiments; human; 1 ug/ml
Dominguez Villar M, Gautron A, de Marcken M, Keller M, Hafler D. TLR7 induces anergy in human CD4(+) T cells. Nat Immunol. 2015;16:118-28 pubmed publisher
  • flow cytometry; human
Davey M, Morgan M, Liuzzi A, Tyler C, Khan M, Szakmany T, et al. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. J Immunol. 2014;193:3704-3716 pubmed publisher
  • flow cytometry; human
Meier D, Docena G, Ramisch D, Toscanini U, Berardi G, Gondolesi G, et al. Immunological status of isolated lymphoid follicles after intestinal transplantation. Am J Transplant. 2014;14:2148-58 pubmed publisher
  • blocking or activating experiments; human; 1 ug/ml
Kivisakk P, Francois K, Mbianda J, Gandhi R, Weiner H, Khoury S. Effect of natalizumab treatment on circulating plasmacytoid dendritic cells: a cross-sectional observational study in patients with multiple sclerosis. PLoS ONE. 2014;9:e103716 pubmed publisher
  • flow cytometry; mouse; fig 3
Borsellino G, Kleinewietfeld M, Di Mitri D, Sternjak A, Diamantini A, Giometto R, et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood. 2007;110:1225-32 pubmed
Thomas S, Mohammed F, Reijmers R, Woolston A, Stauss T, Kennedy A, et al. Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function. Nat Commun. 2019;10:4451 pubmed publisher
Kim D, Kim H, Choi Y, Kim S, Lee J, Sung K, et al. Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancer. Exp Mol Med. 2019;51:94 pubmed publisher
Sueyoshi K, Ledderose C, Shen Y, Lee A, Shapiro N, Junger W. Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors. J Biol Chem. 2019;294:6283-6293 pubmed publisher
Yi J, Balagopalan L, Nguyen T, McIntire K, Samelson L. TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps. Nat Commun. 2019;10:277 pubmed publisher
Keskin D, Anandappa A, Sun J, Tirosh I, Mathewson N, Li S, et al. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature. 2019;565:234-239 pubmed publisher
Harper I, Gjorgjimajkoska O, Siu J, Parmar J, Mulder A, Claas F, et al. Prolongation of allograft survival by passenger donor regulatory T cells. Am J Transplant. 2019;19:1371-1379 pubmed publisher
Cardinez C, Miraghazadeh B, Tanita K, Da Silva E, Hoshino A, Okada S, et al. Gain-of-function IKBKB mutation causes human combined immune deficiency. J Exp Med. 2018;215:2715-2724 pubmed publisher
Lahaye X, Gentili M, Silvin A, Conrad C, Picard L, Jouve M, et al. NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation. Cell. 2018;175:488-501.e22 pubmed publisher
Seren S, Rashed Abouzaid M, Eulenberg Gustavus C, Hirschfeld J, Nasr Soliman H, Jerke U, et al. Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis. J Biol Chem. 2018;293:12415-12428 pubmed publisher
Ledderose C, Liu K, Kondo Y, Slubowski C, Dertnig T, Denicoló S, et al. Purinergic P2X4 receptors and mitochondrial ATP production regulate T cell migration. J Clin Invest. 2018;128:3583-3594 pubmed publisher
Balagopalan L, Yi J, Nguyen T, McIntire K, Harned A, Narayan K, et al. Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation. Nat Commun. 2018;9:2013 pubmed publisher
James N, Cantillo E, Oliver M, Rowswell Turner R, Ribeiro J, Kim K, et al. HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells. Clin Exp Immunol. 2018;193:327-340 pubmed publisher
Clayton K, Collins D, Lengieza J, Ghebremichael M, Dotiwala F, Lieberman J, et al. Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system. Nat Immunol. 2018;19:475-486 pubmed publisher
Kirchhof J, Petrakova L, Brinkhoff A, Benson S, Schmidt J, Unteroberdörster M, et al. Learned immunosuppressive placebo responses in renal transplant patients. Proc Natl Acad Sci U S A. 2018;115:4223-4227 pubmed publisher
Silveira G, Wowk P, Cataneo A, Dos Santos P, Delgobo M, Stimamiglio M, et al. Human T Lymphocytes Are Permissive for Dengue Virus Replication. J Virol. 2018;92: pubmed publisher
Giardino Torchia M, Dutta D, Mittelstadt P, Guha J, Gaida M, Fish K, et al. Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome. Proc Natl Acad Sci U S A. 2018;115:2174-2179 pubmed publisher
Schmitt K, Charlins P, Veselinovic M, Kinner Bibeau L, Hu S, Curlin J, et al. Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model. Virology. 2018;515:235-242 pubmed publisher
Liaskou E, Jeffery L, Chanouzas D, Soskic B, Seldin M, Harper L, et al. Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals. Sci Rep. 2017;7:7652 pubmed publisher
Veenstra M, Williams D, Calderon T, Anastos K, Morgello S, Berman J. Frontline Science: CXCR7 mediates CD14+CD16+ monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS. J Leukoc Biol. 2017;102:1173-1185 pubmed publisher
Das A, Rouault Pierre K, Kamdar S, Gomez Tourino I, Wood K, Donaldson I, et al. Adaptive from Innate: Human IFN-γ+CD4+ T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults. J Immunol. 2017;199:1696-1705 pubmed publisher
Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
Almeida V, Avelar Freitas B, Santos M, Costa L, Silva T, Pereira W, et al. Inhibitory effect of the Pseudobrickellia brasiliensis (Spreng) R.M. King & H. Rob. aqueous extract on human lymphocyte proliferation and IFN-? and TNF-? production in vitro. Braz J Med Biol Res. 2017;50:e5163 pubmed publisher
Chao M, Gentles A, Chatterjee S, Lan F, Reinisch A, Corces M, et al. Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease. Cell Stem Cell. 2017;20:329-344.e7 pubmed publisher
Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, et al. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis. J Clin Invest. 2015;125:739-51 pubmed publisher
Schmitt N, Liu Y, Bentebibel S, Munagala I, Bourdery L, Venuprasad K, et al. The cytokine TGF-? co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells. Nat Immunol. 2014;15:856-65 pubmed publisher
Wege A, Schmidt M, Ueberham E, Ponnath M, Ortmann O, Brockhoff G, et al. Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies. MAbs. 2014;6:968-77 pubmed publisher
O Connor G, Vivian J, Widjaja J, Bridgeman J, Gostick E, Lafont B, et al. Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. J Immunol. 2014;192:2875-84 pubmed publisher
Lehmann C, Jung N, Förster K, Koch N, Leifeld L, Fischer J, et al. Longitudinal analysis of distribution and function of plasmacytoid dendritic cells in peripheral blood and gut mucosa of HIV infected patients. J Infect Dis. 2014;209:940-9 pubmed publisher
deSouza N, Cui J, Dura M, McDonald T, Marks A. A function for tyrosine phosphorylation of type 1 inositol 1,4,5-trisphosphate receptor in lymphocyte activation. J Cell Biol. 2007;179:923-34 pubmed
Ito T, Wang Y, Duramad O, Hori T, Delespesse G, Watanabe N, et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med. 2005;202:1213-23 pubmed
Viglietta V, Baecher Allan C, Weiner H, Hafler D. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med. 2004;199:971-9 pubmed
Bunnell S, Hong D, Kardon J, Yamazaki T, McGlade C, Barr V, et al. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J Cell Biol. 2002;158:1263-75 pubmed
Reignat S, Webster G, Brown D, Ogg G, King A, Seneviratne S, et al. Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection. J Exp Med. 2002;195:1089-101 pubmed
Li Z, Calzada M, Sipes J, Cashel J, Krutzsch H, Annis D, et al. Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior. J Cell Biol. 2002;157:509-19 pubmed
Manninen A, Saksela K. HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells. J Exp Med. 2002;195:1023-32 pubmed
product information
Cat.# :
555337
Brand :
BD Pharmingen
Name :
CD3
Format :
Purified
Clone :
HIT3a
Isotype :
Ms IgG 2a
React :
Hu
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.1 mg
Status :
RUO
List Price :
121.00 USD
more info or order :
company information