product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD3 Molecular Complex
catalog :
555273
quantity :
0.5 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
17A2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other, mass cytometry
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4d
Kim M, Borcherding N, Ahmed K, Voigt A, Vishwakarma A, Kolb R, et al. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021;12:5764 pubmed publisher
  • mass cytometry; mouse
Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3c
Une H, Yamasaki R, Nagata S, Yamaguchi H, Nakamuta Y, Indiasari U, et al. Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination. J Neuroinflammation. 2021;18:126 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s3b
Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed publisher
  • flow cytometry; mouse; 1:167; loading ...; fig s6a
Sanchez Felipe L, Vercruysse T, Sharma S, Ma J, Lemmens V, Van Looveren D, et al. A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate. Nature. 2021;590:320-325 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4f
Luoni M, Giannelli S, Indrigo M, Niro A, Massimino L, Iannielli A, et al. Whole brain delivery of an instability-prone Mecp2 transgene improves behavioral and molecular pathological defects in mouse models of Rett syndrome. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2s1b
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • mass cytometry; mouse; 1.5 ug/ml; loading ...; fig 5d
Guo C, Allen B, Hiam K, Dodd D, Van Treuren W, Higginbottom S, et al. Depletion of microbiome-derived molecules in the host using Clostridium genetics. Science. 2019;366: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Casagrande F, de Souza Ferreira S, Nunes F, Romera L, Dos Santos S, Tessaro F, et al. Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs. J Diabetes Res. 2018;2018:6209694 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2e
Qian G, Jiang W, Zou B, Feng J, Cheng X, Gu J, et al. LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma. J Exp Med. 2018;215:2397-2412 pubmed publisher
  • flow cytometry; mouse; loading ...
Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2
Torcellan T, Hampton H, Bailey J, Tomura M, Brink R, Chtanova T. In vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors. Proc Natl Acad Sci U S A. 2017;114:5677-5682 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4i
Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed publisher
  • flow cytometry; mouse; fig 5a
Lund M, Greer J, Dixit A, Alvarado R, McCauley Winter P, To J, et al. A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis. Sci Rep. 2016;6:37789 pubmed publisher
  • flow cytometry; mouse; loading ...
Herrmann O, Schemionek M. Tumor Suppressor Analysis in CML. Methods Mol Biol. 2016;1465:87-94 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig s3
  • western blot; human; 1:1000; fig 5g
Zhang Y, Velez Delgado A, Mathew E, Li D, Mendez F, Flannagan K, et al. Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer. Gut. 2017;66:124-136 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Chikh G, Luu R, Patel S, Davis H, Weeratna R. Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences. Vaccines (Basel). 2016;4: pubmed publisher
  • flow cytometry; mouse; fig 3
Maelfait J, Roose K, Vereecke L, Mc Guire C, Sze M, Schuijs M, et al. A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection. PLoS Pathog. 2016;12:e1005410 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6a
Ito T, Itakura J, Takahashi S, Sato M, Mino M, Fushimi S, et al. Sprouty-Related Ena/Vasodilator-Stimulated Phosphoprotein Homology 1-Domain-Containing Protein-2 Critically Regulates Influenza A Virus-Induced Pneumonia. Crit Care Med. 2016;44:e530-43 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4B
Everts B, Tussiwand R, Dreesen L, Fairfax K, Huang S, Smith A, et al. Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12. J Exp Med. 2016;213:35-51 pubmed publisher
  • flow cytometry; mouse; fig 2b
  • flow cytometry; human; loading ...; fig 2b
Wei R, Hu Y, Dong F, Xu X, Hu A, Gao G. Hepatoma cell-derived leptin downregulates the immunosuppressive function of regulatory T-cells to enhance the anti-tumor activity of CD8+ T-cells. Immunol Cell Biol. 2016;94:388-99 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig s10
Vicuña L, Strochlic D, Latremoliere A, Bali K, Simonetti M, Husainie D, et al. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015;21:518-23 pubmed publisher
  • other; mouse; fig 6
Wirsdörfer F, Bangen J, Pastille E, Hansen W, Flohé S. Breaking the co-operation between bystander T-cells and natural killer cells prevents the development of immunosuppression after traumatic skeletal muscle injury in mice. Clin Sci (Lond). 2015;128:825-38 pubmed publisher
  • flow cytometry; human
Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, et al. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection. J Immunol. 2015;194:1819-31 pubmed publisher
  • flow cytometry; mouse
Castro Rojas C, Deason K, Hussain R, Hayardeny L, Cravens P, Yarovinsky F, et al. Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance. J Neuroimmunol. 2014;276:232-5 pubmed publisher
  • flow cytometry; mouse
Zhang Y, Yan W, Mathew E, Bednar F, Wan S, Collins M, et al. CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice. Cancer Immunol Res. 2014;2:423-35 pubmed publisher
  • flow cytometry; mouse
Pilling D, Gomer R. Persistent lung inflammation and fibrosis in serum amyloid P component (APCs-/-) knockout mice. PLoS ONE. 2014;9:e93730 pubmed publisher
  • flow cytometry; mouse
Przewoznik M, Hömberg N, Naujoks M, Pötzl J, Münchmeier N, Brenner C, et al. Recruitment of natural killer cells in advanced stages of endogenously arising B-cell lymphoma: implications for therapeutic cell transfer. J Immunother. 2012;35:217-22 pubmed publisher
  • immunohistochemistry - frozen section; mouse
  • immunohistochemistry - paraffin section; mouse
Uchida Y, Ke B, Freitas M, Ji H, Zhao D, Benjamin E, et al. The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouse. Hepatology. 2010;51:1363-72 pubmed publisher
Charlaftis N, Suddason T, Wu X, Anwar S, Karin M, Gallagher E. The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines. EMBO J. 2014;33:2581-96 pubmed publisher
Arabzadeh A, Troy T, Turksen K. Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis. BMC Cancer. 2007;7:196 pubmed
product information
Cat.# :
555273
Brand :
BD Pharmingen
Name :
CD3 Molecular Complex
Format :
Purified
Clone :
17A2
Isotype :
Rat IgG 2b
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.5 mg
Status :
RUO
more info or order :
company information