product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
IL-2
catalog :
554562
quantity :
0.5 mg
price :
335.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MQ1-17H12
reactivity :
African green monkey, human, Rhesus monkey
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 45
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 2a
Yang T, St John L, Garber H, Kerros C, Ruisaard K, Clise Dwyer K, et al. Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation. J Immunol. 2018;201:1389-1399 pubmed publisher
  • flow cytometry; African green monkey; fig s4b
Nishimura Y, Gautam R, Chun T, Sadjadpour R, Foulds K, Shingai M, et al. Early antibody therapy can induce long-lasting immunity to SHIV. Nature. 2017;543:559-563 pubmed publisher
  • flow cytometry; human; loading ...
Neumann L, Mueller M, Moos V, Heller F, Meyer T, Loddenkemper C, et al. Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients. J Immunol. 2016;197:1801-8 pubmed publisher
  • flow cytometry; human; loading ...; fig s1
Coulon P, Richetta C, Rouers A, Blanchet F, Urrutia A, Guerbois M, et al. HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells. J Immunol. 2016;197:517-32 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Loyon R, Picard E, Mauvais O, Queiroz L, Mougey V, Pallandre J, et al. IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner. J Immunol. 2016;197:85-96 pubmed publisher
  • flow cytometry; human; loading ...; tbl 2
Graves S, Kouriba B, Diarra I, Daou M, Niangaly A, Coulibaly D, et al. Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate. Vaccine. 2016;34:2546-55 pubmed publisher
  • flow cytometry; Rhesus monkey; loading ...
Zurawski G, Zurawski S, Flamar A, Richert L, Wagner R, Tomaras G, et al. Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques. PLoS ONE. 2016;11:e0153484 pubmed publisher
  • flow cytometry; African green monkey; loading ...; fig 5a
Phuah J, Wong E, Gideon H, Maiello P, Coleman M, Hendricks M, et al. Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques. Infect Immun. 2016;84:1301-1311 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Li L, Jiang Y, Lao S, Yang B, Yu S, Zhang Y, et al. Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12. PLoS ONE. 2016;11:e0147356 pubmed publisher
  • flow cytometry; Rhesus monkey; fig 3
Bolton D, Pegu A, Wang K, McGinnis K, Nason M, Foulds K, et al. Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs. J Virol. 2016;90:1321-32 pubmed publisher
  • flow cytometry; human; fig s2
Paris R, Petrovas C, Ferrando Martinez S, Moysi E, Boswell K, Archer E, et al. Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression. PLoS ONE. 2015;10:e0144767 pubmed publisher
  • flow cytometry; human
Riou C, Tanko R, Soares A, Masson L, Werner L, Garrett N, et al. Restoration of CD4+ Responses to Copathogens in HIV-Infected Individuals on Antiretroviral Therapy Is Dependent on T Cell Memory Phenotype. J Immunol. 2015;195:2273-2281 pubmed publisher
  • flow cytometry; human; 4:100; fig 3b
Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
  • flow cytometry; human
Huss D, Mehta D, Sharma A, You X, Riester K, Sheridan J, et al. In vivo maintenance of human regulatory T cells during CD25 blockade. J Immunol. 2015;194:84-92 pubmed
  • flow cytometry; human
Kamburova E, Koenen H, van den Hoogen M, Baas M, Joosten I, Hilbrands L. Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy. PLoS ONE. 2014;9:e112658 pubmed publisher
  • flow cytometry; human
Payne T, Blackinton J, Frisbee A, Pickeral J, Sawant S, Vandergrift N, et al. Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. J Virol. 2014;88:9514-28 pubmed publisher
Finney O, Brakke H, Rawlings Rhea S, Hicks R, Doolittle D, López M, et al. CD19 CAR T cell product and disease attributes predict leukemia remission durability. J Clin Invest. 2019;129:2123-2132 pubmed publisher
Logtenberg M, Jansen J, Raaben M, Toebes M, Franke K, Brandsma A, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nat Med. 2019;25:612-619 pubmed publisher
Amelio P, Portevin D, Hella J, Reither K, Kamwela L, Lweno O, et al. HIV Infection Functionally Impairs Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses. J Virol. 2019;93: pubmed publisher
Pan D, Das A, Srivastav S, Traina Dorge V, Didier P, Pahar B. Lack of T-cell-mediated IL-2 and TNFα production is linked to decreased CD58 expression in intestinal tissue during acute simian immunodeficiency virus infection. J Gen Virol. 2019;100:26-34 pubmed publisher
Egui A, Ledesma D, Pérez Antón E, Montoya A, Gómez I, Robledo S, et al. Phenotypic and Functional Profiles of Antigen-Specific CD4+ and CD8+ T Cells Associated With Infection Control in Patients With Cutaneous Leishmaniasis. Front Cell Infect Microbiol. 2018;8:393 pubmed publisher
Kim C, Hu B, Jadhav R, Jin J, Zhang H, Cavanagh M, et al. Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell Rep. 2018;25:2148-2162.e5 pubmed publisher
Ahmed A, Adiga V, Nayak S, Uday Kumar J, Dhar C, Sahoo P, et al. Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis. PLoS Pathog. 2018;14:e1007289 pubmed publisher
Hasso Agopsowicz M, Scriba T, Hanekom W, Dockrell H, Smith S. Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination. Sci Rep. 2018;8:13086 pubmed publisher
Kronstad L, Seiler C, Vergara R, Holmes S, Blish C. Differential Induction of IFN-? and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-? Response to Influenza A Viruses. J Immunol. 2018;201:2117-2131 pubmed publisher
Sakabe S, Sullivan B, Hartnett J, Robles Sikisaka R, Gangavarapu K, Cubitt B, et al. Analysis of CD8+ T cell response during the 2013-2016 Ebola epidemic in West Africa. Proc Natl Acad Sci U S A. 2018;115:E7578-E7586 pubmed publisher
Wong E, Joslyn L, Grant N, Klein E, Lin P, Kirschner D, et al. Low Levels of T Cell Exhaustion in Tuberculous Lung Granulomas. Infect Immun. 2018;86: pubmed publisher
Otta D, de Araújo F, de Rezende V, Souza Fagundes E, Eloi Santos S, Costa Silva M, et al. Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity. Antimicrob Agents Chemother. 2018;62: pubmed publisher
Pawlak E, Dirk B, Jacob R, Johnson A, Dikeakos J. The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells. Retrovirology. 2018;15:6 pubmed publisher
Rivino L, Le Bert N, Gill U, Kunasegaran K, Cheng Y, Tan D, et al. Hepatitis B virus-specific T cells associate with viral control upon nucleos(t)ide-analogue therapy discontinuation. J Clin Invest. 2018;128:668-681 pubmed publisher
Pernas M, Tarancón Díez L, Rodríguez Gallego E, Gomez J, Prado J, Casado C, et al. Factors Leading to the Loss of Natural Elite Control of HIV-1 Infection. J Virol. 2018;92: pubmed publisher
Presotto D, Erdes E, Duong M, Allard M, Regamey P, Quadroni M, et al. Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms. Front Immunol. 2017;8:1564 pubmed publisher
Younan P, Iampietro M, Nishida A, Ramanathan P, Santos R, Dutta M, et al. Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm. MBio. 2017;8: pubmed publisher
Sauermann U, Radaelli A, Stolte Leeb N, Raue K, Bissa M, Zanotto C, et al. Vector Order Determines Protection against Pathogenic Simian Immunodeficiency Virus Infection in a Triple-Component Vaccine by Balancing CD4+ and CD8+ T-Cell Responses. J Virol. 2017;91: pubmed publisher
Schmueck Henneresse M, Omer B, Shum T, Tashiro H, Mamonkin M, Lapteva N, et al. Comprehensive Approach for Identifying the T Cell Subset Origin of CD3 and CD28 Antibody-Activated Chimeric Antigen Receptor-Modified T Cells. J Immunol. 2017;199:348-362 pubmed publisher
Julg B, Pegu A, Abbink P, Liu J, Brinkman A, Molloy K, et al. Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys. J Virol. 2017;91: pubmed publisher
Vinton C, Ortiz A, Calantone N, Mudd J, Deléage C, Morcock D, et al. Cytotoxic T Cell Functions Accumulate When CD4 Is Downregulated by CD4+ T Cells in African Green Monkeys. J Immunol. 2017;198:4403-4412 pubmed publisher
Zurawski G, Shen X, Zurawski S, Tomaras G, Montefiori D, Roederer M, et al. Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses. J Virol. 2017;91: pubmed publisher
García Arriaza J, Perdiguero B, Heeney J, Seaman M, Montefiori D, Yates N, et al. HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specif. J Virol. 2017;91: pubmed publisher
Hartigan O Connor D, Abel K, McCune J. Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression. J Exp Med. 2007;204:2679-92 pubmed
Lichterfeld M, Kaufmann D, Yu X, Mui S, Addo M, Johnston M, et al. Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med. 2004;200:701-12 pubmed
Dieckmann D, Bruett C, Ploettner H, Lutz M, Schuler G. Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med. 2002;196:247-53 pubmed
Kim C, Rott L, Clark Lewis I, Campbell D, Wu L, Butcher E. Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells. J Exp Med. 2001;193:1373-81 pubmed
Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med. 2001;193:1303-10 pubmed
Moreau Aubry A, Le Guiner S, Labarriere N, Gesnel M, Jotereau F, Breathnach R. A processed pseudogene codes for a new antigen recognized by a CD8(+) T cell clone on melanoma. J Exp Med. 2000;191:1617-24 pubmed
product information
Cat.# :
554562
Brand :
BD Pharmingen
Name :
IL-2
Format :
NA/LE
Clone :
MQ1-17H12
Isotype :
Rat IgG 2a
React :
Hu
Conc :
1.0 mg/ml
Apps :
IC/FCM , Neu
Size :
0.5 mg
Status :
RUO
List Price :
335.00 USD
more info or order :
company information