product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
p53
catalog :
554293
quantity :
0.1 mg
price :
268.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DO-1

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 5c
Oliver D, Ji H, Liu P, Gasparian A, Gardiner E, Lee S, et al. Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Sci Rep. 2017;7:43023 pubmed publisher
  • western blot; human; 1:10,000; loading ...; fig 2a, 2e
Hölzer K, Drucker E, Roessler S, Dauch D, Heinzmann F, Waldburger N, et al. Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer. Am J Pathol. 2017;187:228-235 pubmed publisher
  • western blot; human; 1:500; fig 1
Honegger A, Schilling D, Bastian S, Sponagel J, Kuryshev V, Sultmann H, et al. Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells. PLoS Pathog. 2015;11:e1004712 pubmed publisher
  • western blot; human; 1:6000; fig s7
Ochi T, Blackford A, Coates J, Jhujh S, Mehmood S, Tamura N, et al. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science. 2015;347:185-8 pubmed publisher
  • chromatin immunoprecipitation; human; fig 1
Long J, Schoonen P, Graczyk D, O'Prey J, Ryan K. p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death. Oncogene. 2015;34:5152-62 pubmed publisher
  • western blot; human
Huang Y, Chuang A, Hao H, Talbot C, Sen T, Trink B, et al. Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells. Cell Death Differ. 2011;18:1220-30 pubmed publisher
Muller I, Beissert S, Kulms D. Anti-apoptotic NF-κB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production. J Invest Dermatol. 2015;135:851-60 pubmed publisher
Mrschtik M, O'Prey J, Lao L, Long J, Beaumatin F, Strachan D, et al. DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose. Cell Death Differ. 2015;22:1714-26 pubmed publisher
Mahmoudi S, Henriksson S, Farnebo L, Roberg K, Farnebo M. WRAP53 promotes cancer cell survival and is a potential target for cancer therapy. Cell Death Dis. 2011;2:e114 pubmed publisher
Schultz J, Ibrahim S, Vera J, Kunz M. 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence. Mol Cancer. 2009;8:53 pubmed publisher
Li D, Yallowitz A, Ozog L, Marchenko N. A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress. Cell Death Dis. 2014;5:e1194 pubmed publisher
Rodier F, Coppe J, Patil C, Hoeijmakers W, Muñoz D, Raza S, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol. 2009;11:973-9 pubmed publisher
Silden E, Hjelle S, Wergeland L, Sulen A, Andresen V, Bourdon J, et al. Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines. PLoS ONE. 2013;8:e56276 pubmed publisher
product information
Cat.# :
554293
Brand :
BD Pharmingen
Name :
p53
Format :
Purified
Clone :
DO-1
Isotype :
Ms IgG 2a
React :
Hu , Bov
Conc :
0.5 mg/ml
Apps :
IHC(F)* , IHC(Fr) , IP , WB
Size :
0.1 mg
Status :
RUO
List Price :
268.00 USD
more info or order :
company information
BD Biosciences