product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Bcl-2
catalog :
554218
quantity :
0.1 mg
price :
268.00 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
3F11
reactivity :
human, mouse
application :
western blot, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 5a
Hobeika E, Dautzenberg M, Levit Zerdoun E, Pelanda R, Reth M. Conditional Selection of B Cells in Mice With an Inducible B Cell Development. Front Immunol. 2018;9:1806 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Khan A, Carpenter B, Santos e Sousa P, Pospori C, Khorshed R, Griffin J, et al. Redirection to the bone marrow improves T cell persistence and antitumor functions. J Clin Invest. 2018;128:2010-2024 pubmed publisher
  • flow cytometry; mouse; fig 1c
Knudson K, Pritzl C, Saxena V, Altman A, Daniels M, Teixeiro E. NFκB-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality. Proc Natl Acad Sci U S A. 2017;114:E1659-E1667 pubmed publisher
  • western blot; mouse; loading ...; fig s7c
  • western blot; human; loading ...; fig 8b
Adams C, Kim A, Mitra R, Choi J, Gong J, Eischen C. BCL-W has a fundamental role in B cell survival and lymphomagenesis. J Clin Invest. 2017;127:635-650 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2b
Goldstein J, Burlion A, Zaragoza B, Sendeyo K, Polansky J, Huehn J, et al. Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression. PLoS ONE. 2016;11:e0153682 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2a
van der Heijden M, Zimberlin C, Nicholson A, Colak S, Kemp R, Meijer S, et al. Bcl-2 is a critical mediator of intestinal transformation. Nat Commun. 2016;7:10916 pubmed publisher
  • immunoprecipitation; mouse
  • western blot; mouse
Bai L, Chen J, McEachern D, Liu L, Zhou H, Aguilar A, et al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS ONE. 2014;9:e99404 pubmed publisher
  • flow cytometry; mouse
Kim E, Gasper D, Lee S, Plisch E, Svaren J, Suresh M. Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. J Immunol. 2014;192:985-95 pubmed publisher
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed publisher
Chen H, Kanai M, Inoue Yamauchi A, Tu H, Huang Y, Ren D, et al. An interconnected hierarchical model of cell death regulation by the BCL-2 family. Nat Cell Biol. 2015;17:1270-81 pubmed publisher
Ren D, Sun J, Mao L, Ye H, Polonsky K. BH3-only molecule Bim mediates ?-cell death in IRS2 deficiency. Diabetes. 2014;63:3378-87 pubmed publisher
Thiel K, Hernandez L, Dassie J, Thiel W, Liu X, Stockdale K, et al. Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic Acids Res. 2012;40:6319-37 pubmed publisher
Chen R, Valencia I, Zhong F, McColl K, Roderick H, Bootman M, et al. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. J Cell Biol. 2004;166:193-203 pubmed
Zhou H, Li X, Meinkoth J, Pittman R. Akt regulates cell survival and apoptosis at a postmitochondrial level. J Cell Biol. 2000;151:483-94 pubmed
product information
Cat.# :
554218
Brand :
BD Pharmingen
Name :
Bcl-2
Format :
Purified
Clone :
3F11
Isotype :
Ar Ham IgG
React :
Ms
Conc :
0.5 mg/ml
Apps :
WB
Size :
0.1 mg
Status :
RUO
List Price :
268.00 USD
more info or order :
company information