product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Abl
catalog :
554148
quantity :
0.1 mg
price :
278.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8E9
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, other, western blot knockout validation, immunocytochemistry knockout validation
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 5d
Brahmachari S, Ge P, Lee S, Kim D, Karuppagounder S, Kumar M, et al. Activation of tyrosine kinase c-Abl contributes to ?-synuclein-induced neurodegeneration. J Clin Invest. 2016;126:2970-88 pubmed publisher
  • immunocytochemistry knockout validation; mouse; fig 1
Antoku S, Saksela K, Rivera G, Mayer B. A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors. J Cell Sci. 2008;121:3071-82 pubmed publisher
  • immunocytochemistry; mouse; fig 3a
  • western blot; mouse; fig 2i
  • immunoprecipitation; human; loading ...; fig 7b
  • western blot; human; loading ...; fig 4f
Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
  • other; human; loading ...; fig st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 1a
Colecchia D, Rossi M, Sasdelli F, Sanzone S, Strambi A, Chiariello M. MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation. Autophagy. 2015;11:1790-802 pubmed publisher
  • western blot; human; fig 1
Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, et al. Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1? (HP1?) with heterochromatin. J Biol Chem. 2013;288:17871-83 pubmed publisher
  • immunoprecipitation; human
  • western blot; human
Bassermann F, Jahn T, Miething C, Seipel P, Bai R, Coutinho S, et al. Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway. J Biol Chem. 2002;277:12437-45 pubmed
Frietsch J, Kastner C, Grunewald T, Schweigel H, Nollau P, Ziermann J, et al. LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia. Oncotarget. 2014;5:5257-71 pubmed
Gordon M, El Kalla M, Zhao Y, Fiteih Y, Law J, Volodko N, et al. The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury. PLoS ONE. 2013;8:e75483 pubmed publisher
Wu X, Xu Y, Feng K, Tompkins J, Her C. MutS homologue hMSH5: recombinational DSB repair and non-synonymous polymorphic variants. PLoS ONE. 2013;8:e73284 pubmed publisher
Gillis L, Berry D, Minden M, McGlade C, Barber D. Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia. Leukemia. 2013;27:1666-76 pubmed publisher
Greuber E, Pendergast A. Abl family kinases regulate Fc?R-mediated phagocytosis in murine macrophages. J Immunol. 2012;189:5382-92 pubmed publisher
Haaß W, Stehle M, Nittka S, Giehl M, Schrotz King P, Fabarius A, et al. The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib. PLoS ONE. 2012;7:e42863 pubmed publisher
Woodring P, Litwack E, O Leary D, Lucero G, Wang J, Hunter T. Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension. J Cell Biol. 2002;156:879-92 pubmed
product information
Cat.# :
554148
Brand :
BD Pharmingen
Name :
Abl
Format :
Purified
Clone :
8E9
Isotype :
Ms IgG 1
React :
Hu
Conc :
0.5 mg/ml
Apps :
IF , IP , WB
Size :
0.1 mg
Status :
RUO
List Price :
278.00 USD
more info or order :
company information
BD Biosciences