product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD49b/Pan-NK Cells
catalog :
553856
quantity :
0.5 mg
price :
265.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
DX5
reactivity :
mouse
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 63
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Azpilikueta A, Agorreta J, Labiano S, Pérez Gracia J, Sánchez Paulete A, Aznar M, et al. Successful Immunotherapy against a Transplantable Mouse Squamous Lung Carcinoma with Anti-PD-1 and Anti-CD137 Monoclonal Antibodies. J Thorac Oncol. 2016;11:524-36 pubmed publisher
  • flow cytometry; mouse; fig 1
Fujimura N, Xu B, Dalman J, Deng H, Aoyama K, Dalman R. CCR2 inhibition sequesters multiple subsets of leukocytes in the bone marrow. Sci Rep. 2015;5:11664 pubmed publisher
  • flow cytometry; mouse
Spada R, Rojas J, Pérez Yagüe S, Mulens V, Cannata Ortiz P, Bragado R, et al. NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery. J Leukoc Biol. 2015;97:583-98 pubmed publisher
  • flow cytometry; mouse
Dang V, Tanabe K, Tanaka Y, Tokumoto N, Misumi T, Saeki Y, et al. Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. PLoS ONE. 2014;9:e110748 pubmed publisher
  • flow cytometry; mouse
Wickström S, Oberg L, Kärre K, Johansson M. A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells. J Immunol. 2014;192:1577-86 pubmed publisher
  • immunohistochemistry; mouse
Weng T, Huang S, Yen M, Lin C, Chen Y, Lin C, et al. A novel cancer therapeutic using thrombospondin 1 in dendritic cells. Mol Ther. 2014;22:292-302 pubmed publisher
Jung K, Heishi T, Incio J, Huang Y, Beech E, Pinter M, et al. Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer. Proc Natl Acad Sci U S A. 2017;114:10455-10460 pubmed publisher
Kennedy V, Mordhorst B, Gaspers J, Bauer M, Swanson K, Lemley C, et al. Supplementation of corn dried distillers' grains plus solubles to gestating beef cows fed low-quality forage: II. Impacts on uterine blood flow, circulating estradiol-17? and progesterone, and hepatic steroid metabolizing enzyme activity. J Anim Sci. 2016;94:4619-4628 pubmed publisher
Pugh J, Foster S, Sukhina A, Petravic J, Uhrlaub J, Padilla Torres J, et al. Acute systemic DNA damage in youth does not impair immune defense with aging. Aging Cell. 2016;15:686-93 pubmed publisher
Kim H, Lee H, Chang Y, Pichavant M, Shore S, Fitzgerald K, et al. Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity. Nat Med. 2014;20:54-61 pubmed publisher
Chinnery F, King C, Elliott T, Bateman A, James E. Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk. Oncoimmunology. 2012;1:874-883 pubmed
Subrahmanyam R, Du H, Ivanova I, Chakraborty T, Ji Y, Zhang Y, et al. Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions. Nat Immunol. 2012;13:1205-12 pubmed publisher
Blasius A, Barchet W, Cella M, Colonna M. Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cells. J Exp Med. 2007;204:2561-8 pubmed
Palacios E, Weiss A. Distinct roles for Syk and ZAP-70 during early thymocyte development. J Exp Med. 2007;204:1703-15 pubmed
Skokos D, Nussenzweig M. CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J Exp Med. 2007;204:1525-31 pubmed
Shi L, Godfrey W, Lin J, Zhao G, Kao P. NF90 regulates inducible IL-2 gene expression in T cells. J Exp Med. 2007;204:971-7 pubmed
Boos M, Yokota Y, Eberl G, Kee B. Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J Exp Med. 2007;204:1119-30 pubmed
Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, et al. NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs. J Exp Med. 2007;204:893-906 pubmed
Das G, Das J, Eynott P, Zhang Y, Bothwell A, Van Kaer L, et al. Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases. J Exp Med. 2006;203:2603-11 pubmed
Hue S, Ahern P, Buonocore S, Kullberg M, Cua D, McKenzie B, et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J Exp Med. 2006;203:2473-83 pubmed
Krueger A, Garbe A, von Boehmer H. Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J Exp Med. 2006;203:1977-84 pubmed
Garbe A, Krueger A, Gounari F, Zuniga Pflucker J, von Boehmer H. Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate. J Exp Med. 2006;203:1579-90 pubmed
Keir M, Liang S, Guleria I, Latchman Y, Qipo A, Albacker L, et al. Tissue expression of PD-L1 mediates peripheral T cell tolerance. J Exp Med. 2006;203:883-95 pubmed
Rumfelt L, Zhou Y, Rowley B, Shinton S, Hardy R. Lineage specification and plasticity in CD19- early B cell precursors. J Exp Med. 2006;203:675-87 pubmed
Bajenoff M, Breart B, Huang A, Qi H, Cazareth J, Braud V, et al. Natural killer cell behavior in lymph nodes revealed by static and real-time imaging. J Exp Med. 2006;203:619-31 pubmed
Chen S, Kawashima H, Lowe J, Lanier L, Fukuda M. Suppression of tumor formation in lymph nodes by L-selectin-mediated natural killer cell recruitment. J Exp Med. 2005;202:1679-89 pubmed
Ghiringhelli F, Menard C, Terme M, Flament C, Taieb J, Chaput N, et al. CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner. J Exp Med. 2005;202:1075-85 pubmed
Yamane H, Zhu J, Paul W. Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment. J Exp Med. 2005;202:793-804 pubmed
Yoneyama H, Matsuno K, Toda E, Nishiwaki T, Matsuo N, Nakano A, et al. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med. 2005;202:425-35 pubmed
Wei D, Lee H, Park S, Beaudoin L, Teyton L, Lehuen A, et al. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J Exp Med. 2005;202:239-48 pubmed
Bloch Queyrat C, Fondaneche M, Chen R, Yin L, Relouzat F, Veillette A, et al. Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn. J Exp Med. 2005;202:181-92 pubmed
Shin T, Yoshimura K, Shin T, Crafton E, Tsuchiya H, Housseau F, et al. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005;201:1531-41 pubmed
Huntington N, Xu Y, Nutt S, Tarlinton D. A requirement for CD45 distinguishes Ly49D-mediated cytokine and chemokine production from killing in primary natural killer cells. J Exp Med. 2005;201:1421-33 pubmed
Krmpotic A, Hasan M, Loewendorf A, Saulig T, Halenius A, Lenac T, et al. NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145. J Exp Med. 2005;201:211-20 pubmed
Khodoun M, Orekhova T, Potter C, Morris S, Finkelman F. Basophils initiate IL-4 production during a memory T-dependent response. J Exp Med. 2004;200:857-70 pubmed
de Heer H, Hammad H, Soullie T, Hijdra D, Vos N, Willart M, et al. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med. 2004;200:89-98 pubmed
Tarbell K, Yamazaki S, Olson K, Toy P, Steinman R. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med. 2004;199:1467-77 pubmed
Lee K, McNerney M, Stepp S, Mathew P, Schatzle J, Bennett M, et al. 2B4 acts as a non-major histocompatibility complex binding inhibitory receptor on mouse natural killer cells. J Exp Med. 2004;199:1245-54 pubmed
Borowski C, Li X, Aifantis I, Gounari F, von Boehmer H. Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development. J Exp Med. 2004;199:607-15 pubmed
Galkina E, Tanousis K, Preece G, Tolaini M, Kioussis D, Florey O, et al. L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes. J Exp Med. 2003;198:1323-35 pubmed
Stetson D, Mohrs M, Reinhardt R, Baron J, Wang Z, Gapin L, et al. Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med. 2003;198:1069-76 pubmed
Prass K, Meisel C, Höflich C, Braun J, Halle E, Wolf T, et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med. 2003;198:725-36 pubmed
Yotsumoto K, Okoshi Y, Shibuya K, Yamazaki S, Tahara Hanaoka S, Honda S, et al. Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. J Exp Med. 2003;198:223-33 pubmed
Kelly J, Spolski R, Kovanen P, Suzuki T, Bollenbacher J, Pise Masison C, et al. Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma. J Exp Med. 2003;198:79-89 pubmed
Westgaard I, Dissen E, Torgersen K, Lazetic S, Lanier L, Phillips J, et al. The lectin-like receptor KLRE1 inhibits natural killer cell cytotoxicity. J Exp Med. 2003;197:1551-61 pubmed
Lodoen M, Ogasawara K, Hamerman J, Arase H, Houchins J, Mocarski E, et al. NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules. J Exp Med. 2003;197:1245-53 pubmed
Esplugues E, Sancho D, Vega Ramos J, Martinez C, Syrbe U, Hamann A, et al. Enhanced antitumor immunity in mice deficient in CD69. J Exp Med. 2003;197:1093-106 pubmed
Dalod M, Hamilton T, Salomon R, Salazar Mather T, Henry S, Hamilton J, et al. Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. J Exp Med. 2003;197:885-98 pubmed
Vollstedt S, Franchini M, Hefti H, Odermatt B, O Keeffe M, Alber G, et al. Flt3 ligand-treated neonatal mice have increased innate immunity against intracellular pathogens and efficiently control virus infections. J Exp Med. 2003;197:575-84 pubmed
Caramalho I, Lopes Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med. 2003;197:403-11 pubmed
Maloy K, Salaun L, Cahill R, Dougan G, Saunders N, Powrie F. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med. 2003;197:111-9 pubmed
Schrum A, Turka L. The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering. J Exp Med. 2002;196:793-803 pubmed
Sjölin H, Tomasello E, Mousavi Jazi M, Bartolazzi A, Kärre K, Vivier E, et al. Pivotal role of KARAP/DAP12 adaptor molecule in the natural killer cell-mediated resistance to murine cytomegalovirus infection. J Exp Med. 2002;195:825-34 pubmed
Kakimi K, Lane T, Wieland S, Asensio V, Campbell I, Chisari F, et al. Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes. J Exp Med. 2001;194:1755-66 pubmed
Bridgeman A, Stevenson P, Simas J, Efstathiou S. A secreted chemokine binding protein encoded by murine gammaherpesvirus-68 is necessary for the establishment of a normal latent load. J Exp Med. 2001;194:301-12 pubmed
Colucci F, Rosmaraki E, Bregenholt S, Samson S, Di Bartolo V, Turner M, et al. Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms. J Exp Med. 2001;193:1413-24 pubmed
Fehniger T, Suzuki K, Ponnappan A, VanDeusen J, Cooper M, Florea S, et al. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. J Exp Med. 2001;193:219-31 pubmed
Tanamachi D, Hanke T, Takizawa H, Jamieson A, Raulet D. Expression of natural killer receptor alleles at different Ly49 loci occurs independently and is regulated by major histocompatibility complex class I molecules. J Exp Med. 2001;193:307-15 pubmed
Yoneyama H, Matsuno K, Zhang Y, Murai M, Itakura M, Ishikawa S, et al. Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease. J Exp Med. 2001;193:35-49 pubmed
Lohoff M, Duncan G, Ferrick D, Mittrucker H, Bischof S, Prechtl S, et al. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. J Exp Med. 2000;192:325-36 pubmed
Costello P, Cleverley S, Galandrini R, Henning S, Cantrell D. The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis. J Exp Med. 2000;192:77-85 pubmed
Nagaoka H, Gonzalez Aseguinolaza G, Tsuji M, Nussenzweig M. Immunization and infection change the number of recombination activating gene (RAG)-expressing B cells in the periphery by altering immature lymphocyte production. J Exp Med. 2000;191:2113-20 pubmed
Liu T, Khanna K, Chen X, Fink D, Hendricks R. CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J Exp Med. 2000;191:1459-66 pubmed
product information
Cat.# :
553856
Brand :
BD Pharmingen
Name :
CD49b/Pan-NK Cells
Format :
Biotin
Clone :
DX5
Isotype :
Rat IgM
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.5 mg
Status :
RUO
List Price :
265.00 USD
more info or order :
company information
BD Biosciences