product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Panendothelial Cell Antigen
catalog :
553849
quantity :
0.5 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MECA-32
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig s2f
Pantasis S, Friemel J, Brütsch S, Hu Z, Krautbauer S, Liebisch G, et al. Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation. J Cell Sci. 2022;135: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5b, 5g
Dieterich L, Tacconi C, Menzi F, Proulx S, Kapaklikaya K, Hamada M, et al. Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis. Angiogenesis. 2020;23:411-423 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 1a
Cho C, Wang Y, Smallwood P, Williams J, Nathans J. Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3b
Benz F, Wichitnaowarat V, Lehmann M, Germano R, Mihova D, Macas J, et al. Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1b
Wang Y, Sabbagh M, Gu X, Rattner A, Williams J, Nathans J. Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3h
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2b
Cho C, Smallwood P, Nathans J. Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation. Neuron. 2017;95:1056-1073.e5 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; tbl 1
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher
  • immunohistochemistry; mouse; fig s5
Zhou Y, Williams J, Smallwood P, Nathans J. Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina. PLoS ONE. 2015;10:e0143650 pubmed publisher
  • immunohistochemistry; mouse
Rattner A, Wang Y, Zhou Y, Williams J, Nathans J. The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling. Invest Ophthalmol Vis Sci. 2014;55:8614-25 pubmed publisher
  • immunohistochemistry; mouse; fig 3
Zhou Y, Wang Y, TISCHFIELD M, Williams J, Smallwood P, Rattner A, et al. Canonical WNT signaling components in vascular development and barrier formation. J Clin Invest. 2014;124:3825-46 pubmed publisher
Hettich B, Ben Yehuda Greenwald M, Werner S, Leroux J. Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components. Adv Sci (Weinh). 2020;7:2002596 pubmed publisher
Halder S, Milner R. Mild hypoxia triggers transient blood-brain barrier disruption: a fundamental protective role for microglia. Acta Neuropathol Commun. 2020;8:175 pubmed publisher
Noy P, Gavin R, Colombo D, Haining E, Reyat J, Payne H, et al. Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells. Haematologica. 2018;: pubmed publisher
Pitarresi J, Liu X, Avendano A, Thies K, Sizemore G, Hammer A, et al. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Sci Alliance. 2018;1:e201800190 pubmed publisher
Oladipupo S, Kabir A, Smith C, Choi K, Ornitz D. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep. 2018;8:14724 pubmed publisher
Halder S, Kant R, Milner R. Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels. Acta Neuropathol Commun. 2018;6:86 pubmed publisher
Pi L, Fu C, Lu Y, Zhou J, Jorgensen M, Shenoy V, et al. Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension. Front Physiol. 2018;9:138 pubmed publisher
Roudnicky F, Yoon S, Poghosyan S, Schwager S, Poyet C, Vella G, et al. Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels. Oncogene. 2018;37:2573-2585 pubmed publisher
Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher
Guo H, Kazadaeva Y, Ortega F, Manjunath N, Desai T. Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017;430:214-223 pubmed publisher
Decourtye L, Mire E, Clemessy M, Heurtier V, Ledent T, Robinson I, et al. IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice. PLoS ONE. 2017;12:e0170083 pubmed publisher
Mihic Probst D, Ikenberg K, Tinguely M, Schraml P, Behnke S, Seifert B, et al. Tumor cell plasticity and angiogenesis in human melanomas. PLoS ONE. 2012;7:e33571 pubmed publisher
Nolan Stevaux O, Truitt M, Pahler J, Olson P, Guinto C, Lee D, et al. Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes. Genes Cancer. 2010;1:125-41 pubmed publisher
Kümin A, Schafer M, Epp N, Bugnon P, Born Berclaz C, Oxenius A, et al. Peroxiredoxin 6 is required for blood vessel integrity in wounded skin. J Cell Biol. 2007;179:747-60 pubmed
Chavakis E, Aicher A, Heeschen C, Sasaki K, Kaiser R, El Makhfi N, et al. Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells. J Exp Med. 2005;201:63-72 pubmed
Ibe S, Qin Z, Schuler T, Preiss S, Blankenstein T. Tumor rejection by disturbing tumor stroma cell interactions. J Exp Med. 2001;194:1549-59 pubmed
product information
Cat.# :
553849
Brand :
BD Pharmingen
Name :
Panendothelial Cell Antigen
Format :
Purified
Clone :
MECA-32
Isotype :
Rat IgG 2a
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.5 mg
Status :
RUO
more info or order :
company information