product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD41
catalog :
553847
quantity :
0.5 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MWReg30
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; 2 mg/kg; fig 2c
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2e
Shan Z, Li L, Atkins C, Wang M, Wen Y, Jeong J, et al. Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment. elife. 2021;10: pubmed publisher
  • flow cytometry; mouse; loading ...
Lissner M, Cumnock K, Davis N, Vilches Moure J, Basak P, Navarrete D, et al. Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; fig 2e
Beutier H, Hechler B, Godon O, Wang Y, Gillis C, de Chaisemartin L, et al. Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis. Sci Immunol. 2018;3: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1s1b
Chapple R, Hu T, Tseng Y, Liu L, Kitano A, Luu V, et al. ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response. elife. 2018;7: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b, s2b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3a
Yu P, Xiong T, Tenedero C, Lebeau P, Ni R, Macdonald M, et al. Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering. Arterioscler Thromb Vasc Biol. 2018;38:26-39 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7d
Cunin P, Penke L, Thon J, Monach P, Jones T, Chang M, et al. Megakaryocytes compensate for Kit insufficiency in murine arthritis. J Clin Invest. 2017;127:1714-1724 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2i
Lefrançais E, Ortiz Muñoz G, Caudrillier A, Mallavia B, Liu F, Sayah D, et al. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors. Nature. 2017;544:105-109 pubmed publisher
  • flow cytometry; mouse; fig 6
Deng W, Xu Y, Chen W, Paul D, Syed A, Dragovich M, et al. Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor. Nat Commun. 2016;7:12863 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2c
Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, et al. Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood. 2016;128:2435-2449 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig s3c
Crosswhite P, Podsiadlowska J, Curtis C, Gao S, Xia L, Srinivasan R, et al. CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity. J Clin Invest. 2016;126:2254-66 pubmed publisher
  • flow cytometry; mouse; 1:100; fig 7
Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
Vogel S, Bodenstein R, Chen Q, Feil S, Feil R, Rheinlaender J, et al. Platelet-derived HMGB1 is a critical mediator of thrombosis. J Clin Invest. 2015;125:4638-54 pubmed publisher
  • flow cytometry; mouse; loading ...; tbl 1
Okimura K, Maeta K, Kobayashi N, Goto M, Kano N, Ishihara T, et al. Characterization of ASKP1240, a fully human antibody targeting human CD40 with potent immunosuppressive effects. Am J Transplant. 2014;14:1290-9 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:300
Cedervall J, Zhang Y, Ringvall M, Thulin A, Moustakas A, Jahnen Dechent W, et al. HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment. Angiogenesis. 2013;16:889-902 pubmed publisher
  • blocking or activating experiments; mouse; fig 6
  • immunocytochemistry; mouse; fig 6
Gekas C, Graf T. CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood. 2013;121:4463-72 pubmed publisher
Pariser D, Hilt Z, Ture S, Blick Nitko S, Looney M, Cleary S, et al. Lung megakaryocytes are immune modulatory cells. J Clin Invest. 2021;131: pubmed publisher
Zheng W, Zhang H, Zhao D, Zhang J, Pollard J. Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression. Cell Rep. 2019;29:1747-1755.e4 pubmed publisher
Tomaiuolo M, Matzko C, Poventud Fuentes I, Weisel J, Brass L, Stalker T. Interrelationships between structure and function during the hemostatic response to injury. Proc Natl Acad Sci U S A. 2019;116:2243-2252 pubmed publisher
Hurtado B, Trakala M, Ximénez Embún P, El Bakkali A, Partida D, Sanz Castillo B, et al. Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets. J Clin Invest. 2018;128:5351-5367 pubmed publisher
Lewis B, Leontyev D, Neschadim A, Blacquière M, Branch D. GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out. Clin Exp Immunol. 2018;193:293-301 pubmed publisher
Chan H, Huang H, Sun D, Lee C, Lien T, Chang H. TRPM8 and RAAS-mediated hypertension is critical for cold-induced immunosuppression in mice. Oncotarget. 2018;9:12781-12795 pubmed publisher
Spirig R, Campbell I, Koernig S, Chen C, Lewis B, BUTCHER R, et al. rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs. J Immunol. 2018;200:2542-2553 pubmed publisher
Shan Z, Liu X, Chen Y, Wang M, Gao Y, Xu L, et al. Chitinase 3-like-1 Promotes Intrahepatic Activation of Coagulation Through Induction of Tissue Factor in Mice. Hepatology. 2017;: pubmed publisher
Jin R, Xiao A, Song Z, Yu S, Li J, Cui M, et al. Platelet CD40 Mediates Leukocyte Recruitment and Neointima Formation after Arterial Denudation Injury in Atherosclerosis-Prone Mice. Am J Pathol. 2018;188:252-263 pubmed publisher
Gibb D, Liu J, Natarajan P, Santhanakrishnan M, Madrid D, Eisenbarth S, et al. Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice. J Immunol. 2017;199:1041-1050 pubmed publisher
Hayes V, Johnston I, Arepally G, McKenzie S, Cines D, Rauova L, et al. Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia. J Clin Invest. 2017;127:1090-1098 pubmed publisher
Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester Beltrán J, et al. Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest. 2017;127:814-829 pubmed publisher
Vitkov L, Krautgartner W, Obermayer A, Stoiber W, Hannig M, Klappacher M, et al. The initial inflammatory response to bioactive implants is characterized by NETosis. PLoS ONE. 2015;10:e0121359 pubmed publisher
Wilkinson A, Kawata V, Schütte J, Gao X, Antoniou S, Baumann C, et al. Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification. Development. 2014;141:4018-30 pubmed publisher
Mott P, Lazarus A. CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis. PLoS ONE. 2013;8:e65805 pubmed publisher
Massberg S, Konrad I, Schürzinger K, Lorenz M, Schneider S, Zohlnhoefer D, et al. Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo. J Exp Med. 2006;203:1221-33 pubmed
Cobas M, Wilson A, Ernst B, Mancini S, MacDonald H, Kemler R, et al. Beta-catenin is dispensable for hematopoiesis and lymphopoiesis. J Exp Med. 2004;199:221-9 pubmed
Tchernychev B, Furie B, Furie B. Peritoneal macrophages express both P-selectin and PSGL-1. J Cell Biol. 2003;163:1145-55 pubmed
Sperandio M, Smith M, Forlow S, Olson T, Xia L, McEver R, et al. P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules. J Exp Med. 2003;197:1355-63 pubmed
product information
Cat.# :
553847
Brand :
BD Pharmingen
Name :
CD41
Format :
Purified
Clone :
MWReg30
Isotype :
Rat IgG 1
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.5 mg
Status :
RUO
more info or order :
company information