product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD80
catalog :
553767
quantity :
0.5 mg
price :
255.00 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
16-10A1
reactivity :
human, mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 79
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 4:100; loading ...; fig 2a
Vega Angeles V, Terrazas L, Ledesma Soto Y, Jimenez L, Landa A. Taenia solium glutathione transferase fraction activates macrophages and favors the development of Th1-type response. Biosci Rep. 2019;39: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5d
Aarts S, Seijkens T, Kusters P, Van Tiel C, Reiche M, den Toom M, et al. Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis. J Pathol. 2019;247:471-480 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6a
Alam M, Yang D, Trivett A, Meyer T, Oppenheim J. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. Front Immunol. 2018;9:2982 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Casagrande F, de Souza Ferreira S, Nunes F, Romera L, Dos Santos S, Tessaro F, et al. Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs. J Diabetes Res. 2018;2018:6209694 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Grist J, Marro B, Skinner D, Syage A, Worne C, Doty D, et al. Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. Eur J Immunol. 2018;48:1199-1210 pubmed publisher
  • flow cytometry; mouse; fig 3
Xu X, Meng Q, Erben U, Wang P, Glauben R, Kuhl A, et al. Myeloid-derived suppressor cells promote B-cell production of IgA in a TNFR2-dependent manner. Cell Mol Immunol. 2017;14:597-606 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s2
Lund M, Greer J, Dixit A, Alvarado R, McCauley Winter P, To J, et al. A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis. Sci Rep. 2016;6:37789 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s1
Hirako I, Ataide M, Faustino L, Assis P, Sorensen E, Ueta H, et al. Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria. Nat Commun. 2016;7:13277 pubmed publisher
  • flow cytometry; mouse; fig 1d
Chow K, Delconte R, Huntington N, Tarlinton D, Sutherland R, Zhan Y, et al. Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells. J Immunol. 2016;197:2000-8 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5e
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Chikh G, Luu R, Patel S, Davis H, Weeratna R. Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences. Vaccines (Basel). 2016;4: pubmed publisher
  • flow cytometry; mouse
Lee S, Hong S, Verma V, Lee Y, Duong T, Jeong K, et al. Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer. Oncoimmunology. 2016;5:e1081328 pubmed
  • flow cytometry; mouse; fig 4
Mikyšková R, Štěpánek I, Indrová M, Bieblová J, Šímová J, Truxová I, et al. Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy. Int J Oncol. 2016;48:953-64 pubmed publisher
  • flow cytometry; mouse; fig 1
Onodera T, Fukuhara A, Jang M, Shin J, Aoi K, Kikuta J, et al. Adipose tissue macrophages induce PPARγ-high FOXP3(+) regulatory T cells. Sci Rep. 2015;5:16801 pubmed publisher
  • immunocytochemistry; mouse
Riquelme S, Pogu J, Anegon I, Bueno S, Kalergis A. Carbon monoxide impairs mitochondria-dependent endosomal maturation and antigen presentation in dendritic cells. Eur J Immunol. 2015;45:3269-88 pubmed publisher
  • flow cytometry; mouse; fig 2
Buerger S, Herrmann V, Mundt S, Trautwein N, Groettrup M, Basler M. The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection. J Immunol. 2015;195:4106-16 pubmed publisher
  • flow cytometry; mouse
  • flow cytometry; human
Holtzhausen A, Zhao F, Evans K, Tsutsui M, Orabona C, Tyler D, et al. Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy. Cancer Immunol Res. 2015;3:1082-95 pubmed publisher
  • flow cytometry; mouse; fig 4
Jobsri J, Allen A, Rajagopal D, Shipton M, Kanyuka K, Lomonossoff G, et al. Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody. PLoS ONE. 2015;10:e0118096 pubmed publisher
  • immunocytochemistry; mouse
Rattay K, Claude J, Rezavandy E, Matt S, Hofmann T, Kyewski B, et al. Homeodomain-interacting protein kinase 2, a novel autoimmune regulator interaction partner, modulates promiscuous gene expression in medullary thymic epithelial cells. J Immunol. 2015;194:921-8 pubmed publisher
  • flow cytometry; mouse; fig s3
Skripuletz T, Manzel A, Gropengießer K, Schäfer N, Gudi V, Singh V, et al. Pivotal role of choline metabolites in remyelination. Brain. 2015;138:398-413 pubmed publisher
  • flow cytometry; mouse; fig 6
Frossard C, Asigbetse K, Burger D, Eigenmann P. Gut T cell receptor-γδ(+) intraepithelial lymphocytes are activated selectively by cholera toxin to break oral tolerance in mice. Clin Exp Immunol. 2015;180:118-30 pubmed publisher
  • flow cytometry; mouse
Wei F, Yang D, Tewary P, Li Y, Li S, Chen X, et al. The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant. Cancer Res. 2014;74:5989-98 pubmed publisher
  • flow cytometry; mouse
Penaloza MacMaster P, Kamphorst A, Wieland A, Araki K, Iyer S, West E, et al. Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. J Exp Med. 2014;211:1905-18 pubmed publisher
  • flow cytometry; mouse
Lee Chang C, Bodogai M, Moritoh K, Olkhanud P, Chan A, Croft M, et al. Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood. 2014;124:1450-9 pubmed publisher
  • flow cytometry; mouse
Siurala M, Bramante S, Vassilev L, Hirvinen M, Parviainen S, Tähtinen S, et al. Oncolytic adenovirus and doxorubicin-based chemotherapy results in synergistic antitumor activity against soft-tissue sarcoma. Int J Cancer. 2015;136:945-54 pubmed publisher
  • flow cytometry; mouse
Hirayama T, Asano Y, Iida H, Watanabe T, Nakamura T, Goitsuka R. Meis1 is required for the maintenance of postnatal thymic epithelial cells. PLoS ONE. 2014;9:e89885 pubmed publisher
  • flow cytometry; mouse
Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A, et al. Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity. Int Immunol. 2014;26:103-14 pubmed publisher
Goldstein J, Valido A, Lewandowski J, Walker R, Mills M, Messemer K, et al. Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus. Sci Rep. 2019;9:18613 pubmed publisher
To E, Erlich J, Liong F, Luong R, Liong S, Esaq F, et al. MITOCHONDRIAL REACTIVE OXYGEN SPECIES CONTRIBUTE TO PATHOLOGICAL INFLAMMATION DURING INFLUENZA A VIRUS INFECTION IN MICE. Antioxid Redox Signal. 2019;: pubmed publisher
Xiong X, Mathewson N, Li H, Tan M, Fujiwara H, Li H, et al. SAG/RBX2 E3 Ubiquitin Ligase Differentially Regulates Inflammatory Responses of Myeloid Cell Subsets. Front Immunol. 2018;9:2882 pubmed publisher
Ravindranathan S, Nguyen K, Kurtz S, Frazier H, Smith S, Koppolu B, et al. Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines. Breast Cancer Res. 2018;20:126 pubmed publisher
Thyagarajan H, Lancaster J, Lira S, Ehrlich L. CCR8 is expressed by post-positive selection CD4-lineage thymocytes but is dispensable for central tolerance induction. PLoS ONE. 2018;13:e0200765 pubmed publisher
Yakoub A, Schulz R, Seiffert M, Sadek M. Autoantigen-Harboring Apoptotic Cells Hijack the Coinhibitory Pathway of T Cell Activation. Sci Rep. 2018;8:10533 pubmed publisher
Diao J, Gu H, Tang M, Zhao J, Cattral M. Tumor Dendritic Cells (DCs) Derived from Precursors of Conventional DCs Are Dispensable for Intratumor CTL Responses. J Immunol. 2018;201:1306-1314 pubmed publisher
Barik S, Miller M, Cattin Roy A, Ukah T, Zaghouani H. A distinct dendritic cell population arises in the thymus of IL-13Rα1-sufficient but not IL-13Rα1-deficient mice. Cell Immunol. 2018;331:130-136 pubmed publisher
Dzharullaeva A, Tukhvatulin A, Erokhova A, Bandelyuk A, Polyakov N, Solovyev A, et al. Stimulation of Dectin-1 and Dectin-2 during Parenteral Immunization, but Not Mincle, Induces Secretory IgA in Intestinal Mucosa. J Immunol Res. 2018;2018:3835720 pubmed publisher
De Feo D, Merlini A, Brambilla E, Ottoboni L, Laterza C, Menon R, et al. Neural precursor cell-secreted TGF-β2 redirects inflammatory monocyte-derived cells in CNS autoimmunity. J Clin Invest. 2017;127:3937-3953 pubmed publisher
Kim D, Dastidar H, Zhang C, Zemp F, Lau K, Ernst M, et al. Smac mimetics and oncolytic viruses synergize in driving anticancer T-cell responses through complementary mechanisms. Nat Commun. 2017;8:344 pubmed publisher
Lanser A, Rezende R, Rubino S, Lorello P, Donnelly D, Xu H, et al. Disruption of the ATP/adenosine balance in CD39-/- mice is associated with handling-induced seizures. Immunology. 2017;152:589-601 pubmed publisher
Shrestha B, You D, Saravia J, Siefker D, Jaligama S, Lee G, et al. IL-4R? on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection. J Leukoc Biol. 2017;102:153-161 pubmed publisher
Channappanavar R, Fett C, Mack M, Ten Eyck P, Meyerholz D, Perlman S. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. J Immunol. 2017;198:4046-4053 pubmed publisher
Nouri Shirazi M, Bible B, Zeng M, Tamjidi S, Bossart G. Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care. BMC Vet Res. 2017;13:78 pubmed publisher
Brahmakshatriya V, Kuang Y, Devarajan P, Xia J, Zhang W, Vong A, et al. IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo. J Immunol. 2017;198:2819-2833 pubmed publisher
Leeth C, Racine J, Chapman H, Arpa B, Carrillo J, Carrascal J, et al. B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice. Diabetes. 2016;65:1977-1987 pubmed publisher
Graham D, Stephenson L, Lam S, Brim K, Lee H, Bautista J, et al. An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells. J Exp Med. 2007;204:2889-97 pubmed
Nagamachi M, Sakata D, Kabashima K, Furuyashiki T, Murata T, Segi Nishida E, et al. Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1. J Exp Med. 2007;204:2865-74 pubmed
Shimizu K, Kurosawa Y, Taniguchi M, Steinman R, Fujii S. Cross-presentation of glycolipid from tumor cells loaded with alpha-galactosylceramide leads to potent and long-lived T cell mediated immunity via dendritic cells. J Exp Med. 2007;204:2641-53 pubmed
Narni Mancinelli E, Campisi L, Bassand D, Cazareth J, Gounon P, Glaichenhaus N, et al. Memory CD8+ T cells mediate antibacterial immunity via CCL3 activation of TNF/ROI+ phagocytes. J Exp Med. 2007;204:2075-87 pubmed
Zangani M, Frøyland M, Qiu G, Meza Zepeda L, Kutok J, Thompson K, et al. Lymphomas can develop from B cells chronically helped by idiotype-specific T cells. J Exp Med. 2007;204:1181-91 pubmed
Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, et al. NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs. J Exp Med. 2007;204:893-906 pubmed
Fallon P, Ballantyne S, Mangan N, Barlow J, Dasvarma A, Hewett D, et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med. 2006;203:1105-16 pubmed
Wheway J, Mackay C, Newton R, Sainsbury A, Boey D, Herzog H, et al. A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med. 2005;202:1527-38 pubmed
Hessel E, Chu M, Lizcano J, Chang B, Herman N, Kell S, et al. Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. J Exp Med. 2005;202:1563-73 pubmed
Johansson Lindbom B, Svensson M, Pabst O, Palmqvist C, Marquez G, Forster R, et al. Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J Exp Med. 2005;202:1063-73 pubmed
Annacker O, Coombes J, Malmstrom V, Uhlig H, Bourne T, Johansson Lindbom B, et al. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J Exp Med. 2005;202:1051-61 pubmed
Ghiringhelli F, Puig P, Roux S, Parcellier A, Schmitt E, Solary E, et al. Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation. J Exp Med. 2005;202:919-29 pubmed
Dougan S, Salas A, Rava P, Agyemang A, Kaser A, Morrison J, et al. Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells. J Exp Med. 2005;202:529-39 pubmed
Derbinski J, Gäbler J, Brors B, Tierling S, Jonnakuty S, Hergenhahn M, et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med. 2005;202:33-45 pubmed
Yao Y, Li W, Kaplan M, Chang C. Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells. J Exp Med. 2005;201:1899-903 pubmed
Yoshitomi H, Sakaguchi N, Kobayashi K, Brown G, Tagami T, Sakihama T, et al. A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice. J Exp Med. 2005;201:949-60 pubmed
de Heer H, Hammad H, Soullie T, Hijdra D, Vos N, Willart M, et al. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med. 2004;200:89-98 pubmed
Turley S, Poirot L, Hattori M, Benoist C, Mathis D. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J Exp Med. 2003;198:1527-37 pubmed
Boehm T, Scheu S, Pfeffer K, Bleul C. Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. J Exp Med. 2003;198:757-69 pubmed
Brimnes M, Bonifaz L, Steinman R, Moran T. Influenza virus-induced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered, normally nonimmunogenic protein. J Exp Med. 2003;198:133-44 pubmed
Sugita S, Streilein J. Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2003;198:161-71 pubmed
Caramalho I, Lopes Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med. 2003;197:403-11 pubmed
Ocana Morgner C, Mota M, Rodriguez A. Malaria blood stage suppression of liver stage immunity by dendritic cells. J Exp Med. 2003;197:143-51 pubmed
Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig M, Steinman R. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med. 2002;196:1627-38 pubmed
Schiavoni G, Mattei F, Sestili P, Borghi P, Venditti M, Morse H, et al. ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells. J Exp Med. 2002;196:1415-25 pubmed
Scheinecker C, McHugh R, Shevach E, Germain R. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med. 2002;196:1079-90 pubmed
Shi X, Xie C, Kreska D, Richardson J, Mohan C. Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity. J Exp Med. 2002;196:281-92 pubmed
Liang L, Porter E, Sha W. Constitutive expression of the B7h ligand for inducible costimulator on naive B cells is extinguished after activation by distinct B cell receptor and interleukin 4 receptor-mediated pathways and can be rescued by CD40 signaling. J Exp Med. 2002;196:97-108 pubmed
Colino J, Shen Y, Snapper C. Dendritic cells pulsed with intact Streptococcus pneumoniae elicit both protein- and polysaccharide-specific immunoglobulin isotype responses in vivo through distinct mechanisms. J Exp Med. 2002;195:1-13 pubmed
Nakano H, Yanagita M, Gunn M. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med. 2001;194:1171-8 pubmed
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med. 2001;194:769-79 pubmed
Salomon B, Rhee L, Bour Jordan H, Hsin H, Montag A, Soliven B, et al. Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice. J Exp Med. 2001;194:677-84 pubmed
Brown K, Hostager B, Bishop G. Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1). J Exp Med. 2001;193:943-54 pubmed
Vermaelen K, Carro Muino I, Lambrecht B, Pauwels R. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med. 2001;193:51-60 pubmed
Hwang I, Huang J, Kishimoto H, Brunmark A, Peterson P, Jackson M, et al. T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J Exp Med. 2000;191:1137-48 pubmed
product information
Cat.# :
553767
Brand :
BD Pharmingen
Name :
CD80
Format :
Biotin
Clone :
16-10A1
Isotype :
Ar Ham IgG 2
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.5 mg
Status :
RUO
List Price :
255.00 USD
more info or order :
company information