| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunocytochemistry; human; fig s1h
| Sáinz Jaspeado M, Smith R, Plunde O, Pawelzik S, Jin Y, Nordling S, et al. Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium. Circulation. 2021;144:1629-1645 pubmed publisher |
- flow cytometry; human; loading ...; fig s2b
| Amado Azevedo J, van Stalborch A, Valent E, Nawaz K, van Bezu J, Eringa E, et al. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation. Angiogenesis. 2021;: pubmed publisher |
- immunocytochemistry; mouse; 1:100; loading ...; fig 5b
| Schiweck J, Murk K, Ledderose J, Münster Wandowski A, Ornaghi M, Vida I, et al. Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking. Nat Commun. 2021;12:1490 pubmed publisher |
- western blot; mouse; loading ...; fig 2b
| Kashyap R, Balzano M, Lechat B, Lambaerts K, Egea Jimenez A, Lembo F, et al. Syntenin-knock out reduces exosome turnover and viral transduction. Sci Rep. 2021;11:4083 pubmed publisher |
- immunohistochemistry; human; 1:200; loading ...
| Dabelsteen S, Pallesen E, Marinova I, Nielsen M, Adamopoulou M, Rømer T, et al. Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model. Dev Cell. 2020;54:669-684.e7 pubmed publisher |
- immunocytochemistry; human; fig 5i
| Bae H, Hong K, Lee C, Jang C, Lee S, Choe K, et al. Angiopoietin-2-integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance. Nat Commun. 2020;11:2980 pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...; fig 1i
| Sahgal P, Alanko J, Icha J, Paatero I, Hamidi H, Arjonen A, et al. GGA2 and RAB13 promote activity-dependent β1-integrin recycling. J Cell Sci. 2019;132: pubmed publisher |
- immunocytochemistry; human; fig 1f
| Xanthis I, Souilhol C, Serbanovic Canic J, Roddie H, Kalli A, Fragiadaki M, et al. β1 integrin is a sensor of blood flow direction. J Cell Sci. 2019;132: pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100
- flow cytometry; mouse; 1:50; loading ...; fig 1c
| Peuhu E, Salomaa S, De Franceschi N, Potter C, Sundberg J, Pouwels J. Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice. PLoS ONE. 2017;12:e0186628 pubmed publisher |
- immunocytochemistry; human; 1:300; loading ...; fig 2b
| Huet Calderwood C, Rivera Molina F, Iwamoto D, Kromann E, Toomre D, Calderwood D. Novel ecto-tagged integrins reveal their trafficking in live cells. Nat Commun. 2017;8:570 pubmed publisher |
- immunocytochemistry; human; fig 6b
| Lin Y, Ohbayashi N, Hongu T, Katagiri N, Funakoshi Y, Lee H, et al. Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration. Sci Rep. 2017;7:11431 pubmed publisher |
- flow cytometry; mouse; 1:200; loading ...; fig S1A
- immunocytochemistry; mouse; 1:200; loading ...; fig S1C
| Wei X, Wang X, Zhan J, Chen Y, Fang W, Zhang L, et al. Smurf1 inhibits integrin activation by controlling Kindlin-2 ubiquitination and degradation. J Cell Biol. 2017;216:1455-1471 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 1d
| Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, et al. AMPK negatively regulates tensin-dependent integrin activity. J Cell Biol. 2017;216:1107-1121 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s7b
| Jongbloets B, Lemstra S, Schellino R, Broekhoven M, Parkash J, Hellemons A, et al. Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors. Nat Commun. 2017;8:14666 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 5a
| Chen Z, Givens C, Reader J, Tzima E. Haemodynamics Regulate Fibronectin Assembly via PECAM. Sci Rep. 2017;7:41223 pubmed publisher |
- immunocytochemistry; mouse; 1:200; fig 1a
- immunohistochemistry; mouse; 1:200; loading ...; fig s9b
| Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher |
- flow cytometry; mouse; 1:50; fig s3
- immunocytochemistry; human; fig 3
| Barrow McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche B, et al. Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun. 2016;7:11942 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 2
| Freeman S, Christian S, Austin P, Iu I, Graves M, Huang L, et al. Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. J Cell Sci. 2017;130:152-163 pubmed publisher |
- flow cytometry; mouse; fig s1
| Atherton P, Stutchbury B, Wang D, Jethwa D, Tsang R, Meiler Rodriguez E, et al. Vinculin controls talin engagement with the actomyosin machinery. Nat Commun. 2015;6:10038 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 3b
| Doyle A, Carvajal N, Jin A, Matsumoto K, Yamada K. Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions. Nat Commun. 2015;6:8720 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 2c
| Kashyap R, Roucourt B, Lembo F, Fares J, Carcavilla A, Restouin A, et al. Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells. Front Pharmacol. 2015;6:241 pubmed publisher |
- flow cytometry; mouse; 1:100
| Lujan E, Zunder E, Ng Y, Goronzy I, Nolan G, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 2015;521:352-6 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- western blot; mouse
| Saito K, Fukumoto E, Yamada A, Yuasa K, Yoshizaki K, Iwamoto T, et al. Interaction between fibronectin and β1 integrin is essential for tooth development. PLoS ONE. 2015;10:e0121667 pubmed publisher |
- immunocytochemistry; mouse; 1:2500; fig 3
| Qiao X, Roth I, Féraille E, Hasler U. Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. Cell Cycle. 2014;13:3059-75 pubmed publisher |
- flow cytometry; mouse; fig 5
| Sugahara K, Braun G, de Mendoza T, Kotamraju V, French R, Lowy A, et al. Tumor-penetrating iRGD peptide inhibits metastasis. Mol Cancer Ther. 2015;14:120-8 pubmed publisher |
- blocking or activating experiments; mouse
| Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood D, Schwartz M, et al. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. J Biol Chem. 2015;290:409-22 pubmed publisher |
| De Rossi G, Evans A, Kay E, Woodfin A, McKay T, Nourshargh S, et al. Shed syndecan-2 inhibits angiogenesis. J Cell Sci. 2014;127:4788-99 pubmed publisher |
- immunohistochemistry - frozen section; mouse
- immunoprecipitation; mouse
- western blot; mouse
- western blot; rat
| Wakatsuki S, Araki T, Sehara Fujisawa A. Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing ?5 ?1 integrin-ErbB2-focal adhesion kinase complex formation. Genes Cells. 2014;19:66-77 pubmed publisher |
- flow cytometry; human; 1:150
- immunocytochemistry; human; 1:100
- western blot; human; 1:150; fig 5b
| Valtcheva N, Primorac A, Jurisic G, Hollmen M, Detmar M. The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42. J Biol Chem. 2013;288:35736-48 pubmed publisher |
- immunocytochemistry; mouse; fig 8
| Zhong J, Baquiran J, Bonakdar N, Lees J, Ching Y, Pugacheva E, et al. NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS ONE. 2012;7:e35058 pubmed publisher |
| Urner S, Planas Paz L, Hilger L, Henning C, Branopolski A, Kelly Goss M, et al. Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth. EMBO J. 2019;38: pubmed publisher |
| Donnelly S, Cabrera R, Mao S, Christin J, Wu B, Guo W, et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol. 2017;216:4331-4349 pubmed publisher |
| Barbazán J, Alonso Alconada L, Elkhatib N, Geraldo S, Gurchenkov V, Glentis A, et al. Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits. Cancer Res. 2017;77:3431-3441 pubmed publisher |
| Di Russo J, Luik A, Yousif L, Budny S, Oberleithner H, Hofschröer V, et al. Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J. 2017;36:183-201 pubmed publisher |
| Broders Bondon F, Paul Gilloteaux P, Gazquez E, Heysch J, Piel M, Mayor R, et al. Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin. Dev Biol. 2016;414:85-99 pubmed publisher |
| Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher |
| Macek Jilkova Z, Lisowska J, Manet S, Verdier C, Deplano V, Geindreau C, et al. CCM proteins control endothelial β1 integrin dependent response to shear stress. Biol Open. 2014;3:1228-35 pubmed publisher |
| Wang Y, Juan H, Wong Y, Kuo W, Lu Y, Lin S, et al. Protogenin prevents premature apoptosis of rostral cephalic neural crest cells by activating the ?5?1-integrin. Cell Death Dis. 2013;4:e651 pubmed publisher |
| Jeanes A, Wang P, Moreno Layseca P, Paul N, Cheung J, Tsang R, et al. Specific ?-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells. J Biol Chem. 2012;287:24103-12 pubmed publisher |
| Zemskov E, Mikhailenko I, Hsia R, Zaritskaya L, Belkin A. Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes. PLoS ONE. 2011;6:e19414 pubmed publisher |
| Petrich B, Marchese P, Ruggeri Z, Spiess S, Weichert R, Ye F, et al. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007;204:3103-11 pubmed |
| Wang W, Kuo J, Yao C, Chen R. DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals. J Cell Biol. 2002;159:169-79 pubmed |
