product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
IgM
catalog :
553405
quantity :
0.5 mg
price :
165.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
R6-60.2
reactivity :
mouse
application :
ELISA, flow cytometry, other
more info or order :
citations: 39
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:800; loading ...; fig 1e
Grootjans J, Krupka N, Hosomi S, Matute J, Hanley T, Saveljeva S, et al. Epithelial endoplasmic reticulum stress orchestrates a protective IgA response. Science. 2019;363:993-998 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s1d
  • ELISA; mouse; 1:1000
Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1c
Neyt K, GeurtsvanKessel C, Deswarte K, Hammad H, Lambrecht B. Early IL-1 Signaling Promotes iBALT Induction after Influenza Virus Infection. Front Immunol. 2016;7:312 pubmed publisher
  • flow cytometry; mouse; fig 3
Kabat A, Harrison O, Riffelmacher T, Moghaddam A, Pearson C, Laing A, et al. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation. elife. 2016;5:e12444 pubmed publisher
  • flow cytometry; mouse
Sin S, Kim Y, Eason A, Dittmer D. KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice. PLoS Pathog. 2015;11:e1005135 pubmed publisher
  • other; mouse; fig 3a
Ouchida R, Lu Q, Liu J, Li Y, Chu Y, Tsubata T, et al. FcμR interacts and cooperates with the B cell receptor To promote B cell survival. J Immunol. 2015;194:3096-101 pubmed publisher
  • flow cytometry; mouse
Chiu Y, Lin I, Su S, Wang K, Yang S, Tsai D, et al. Transcription factor ABF-1 suppresses plasma cell differentiation but facilitates memory B cell formation. J Immunol. 2014;193:2207-17 pubmed publisher
  • flow cytometry; mouse
Schneppenheim J, Hüttl S, Mentrup T, Lüllmann Rauch R, Rothaug M, Engelke M, et al. The intramembrane proteases signal Peptide peptidase-like 2a and 2b have distinct functions in vivo. Mol Cell Biol. 2014;34:1398-411 pubmed publisher
Delgado Benito V, Rosen D, Wang Q, Gazumyan A, Pai J, Oliveira T, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Mol Cell. 2018;72:636-649.e8 pubmed publisher
Preite S, Cannons J, Radtke A, Vujkovic Cvijin I, Gomez Rodriguez J, Volpi S, et al. Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity. Nat Immunol. 2018;19:986-1000 pubmed publisher
Sin S, Eason A, Bigi R, Kim Y, Kang S, Tan K, et al. Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections. J Virol. 2018;92: pubmed publisher
Avery D, Kane A, Nguyen T, Lau A, Nguyen A, Lenthall H, et al. Germline-activating mutations in PIK3CD compromise B cell development and function. J Exp Med. 2018;215:2073-2095 pubmed publisher
Raso F, Sagadiev S, Du S, Gage E, Arkatkar T, Metzler G, et al. αv Integrins regulate germinal center B cell responses through noncanonical autophagy. J Clin Invest. 2018;128:4163-4178 pubmed publisher
Pardi N, Hogan M, Naradikian M, Parkhouse K, Cain D, Jones L, et al. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. J Exp Med. 2018;215:1571-1588 pubmed publisher
Hwang I, Boularan C, Harrison K, Kehrl J. Gαi Signaling Promotes Marginal Zone B Cell Development by Enabling Transitional B Cell ADAM10 Expression. Front Immunol. 2018;9:687 pubmed publisher
Valentin Torres A, Savarin C, Barnett J, Bergmann C. Blockade of sustained tumor necrosis factor in a transgenic model of progressive autoimmune encephalomyelitis limits oligodendrocyte apoptosis and promotes oligodendrocyte maturation. J Neuroinflammation. 2018;15:121 pubmed publisher
Soto Feliciano Y, Bartlebaugh J, Liu Y, Sanchez Rivera F, Bhutkar A, Weintraub A, et al. PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. Genes Dev. 2017;31:973-989 pubmed publisher
Sindhava V, Oropallo M, Moody K, Naradikian M, Higdon L, Zhou L, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017;127:1651-1663 pubmed publisher
Leech J, Lacey K, Mulcahy M, Medina E, McLoughlin R. IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections. J Immunol. 2017;198:2352-2365 pubmed publisher
Mandal M, Hamel K, Maienschein Cline M, Tanaka A, Teng G, Tuteja J, et al. Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nat Immunol. 2015;16:1094-103 pubmed publisher
Mandal M, Powers S, Maienschein Cline M, Bartom E, Hamel K, Kee B, et al. Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat Immunol. 2011;12:1212-20 pubmed publisher
Brownlie R, Lawlor K, Niederer H, Cutler A, Xiang Z, Clatworthy M, et al. Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb. J Exp Med. 2008;205:883-95 pubmed publisher
Emslie D, D Costa K, Hasbold J, Metcalf D, Takatsu K, Hodgkin P, et al. Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. J Exp Med. 2008;205:409-21 pubmed publisher
Gauduin M, Yu Y, Barabasz A, Carville A, Piatak M, Lifson J, et al. Induction of a virus-specific effector-memory CD4+ T cell response by attenuated SIV infection. J Exp Med. 2006;203:2661-72 pubmed
Matter M, Odermatt B, Yagita H, Nuoffer J, Ochsenbein A. Elimination of chronic viral infection by blocking CD27 signaling. J Exp Med. 2006;203:2145-55 pubmed
Wheway J, Mackay C, Newton R, Sainsbury A, Boey D, Herzog H, et al. A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med. 2005;202:1527-38 pubmed
Ait Azzouzene D, Verkoczy L, Peters J, Gavin A, Skog P, VELA J, et al. An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system. J Exp Med. 2005;201:817-28 pubmed
Galler G, Mundt C, Parker M, Pelanda R, Martensson I, Winkler T. Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components. J Exp Med. 2004;199:1523-32 pubmed
Clayton E, Bardi G, Bell S, Chantry D, Downes C, Gray A, et al. A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med. 2002;196:753-63 pubmed
Xu S, Lam K. Delayed cellular maturation and decreased immunoglobulin kappa light chain production in immature B lymphocytes lacking B cell linker protein. J Exp Med. 2002;196:197-206 pubmed
Yamazaki T, Takeda K, Gotoh K, Takeshima H, Akira S, Kurosaki T. Essential immunoregulatory role for BCAP in B cell development and function. J Exp Med. 2002;195:535-45 pubmed
Schneider P, Takatsuka H, Wilson A, Mackay F, Tardivel A, Lens S, et al. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J Exp Med. 2001;194:1691-7 pubmed
Nakano H, Yanagita M, Gunn M. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med. 2001;194:1171-8 pubmed
Mundt C, Licence S, Shimizu T, Melchers F, Mårtensson I. Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice. J Exp Med. 2001;193:435-45 pubmed
Batten M, Groom J, Cachero T, Qian F, Schneider P, Tschopp J, et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med. 2000;192:1453-66 pubmed
Flaishon L, Hershkoviz R, Lantner F, Lider O, Alon R, Levo Y, et al. Autocrine secretion of interferon gamma negatively regulates homing of immature B cells. J Exp Med. 2000;192:1381-8 pubmed
Cariappa A, Liou H, Horwitz B, Pillai S. Nuclear factor kappa B is required for the development of marginal zone B lymphocytes. J Exp Med. 2000;192:1175-82 pubmed
Murata K, Ishii N, Takano H, Miura S, Ndhlovu L, Nose M, et al. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J Exp Med. 2000;191:365-74 pubmed
Korner H, Cretney E, Wilhelm P, Kelly J, Rollinghoff M, Sedgwick J, et al. Tumor necrosis factor sustains the generalized lymphoproliferative disorder (gld) phenotype. J Exp Med. 2000;191:89-96 pubmed
product information
Cat.# :
553405
Brand :
BD Pharmingen
Name :
IgM
Format :
Purified
Clone :
R6-60.2
Isotype :
Rat IgG 2a
React :
Ms
Conc :
0.5 mg/ml
Apps :
ELISA , FCM
Size :
0.5 mg
Status :
RUO
List Price :
165.00 USD
more info or order :
company information