product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD11b
catalog :
553310
quantity :
0.5 mg
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
M1/70
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry, blocking or activating experiments
more info or order :
citations: 46
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s10
Gao D, Salomonis N, Henderlight M, Woods C, Thakkar K, Grom A, et al. IFN-γ is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome. JCI Insight. 2021;6: pubmed publisher
  • flow cytometry; human; fig s3b
Reis M, Willis G, Fernandez Gonzalez A, Yeung V, Taglauer E, Magaletta M, et al. Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia. Front Immunol. 2021;12:640595 pubmed publisher
  • flow cytometry; mouse; loading ...
Bonilla W, Kirchhammer N, Marx A, Kallert S, Krzyzaniak M, Lu M, et al. Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack. Cell Rep Med. 2021;2:100209 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 3h, 4d
Beins E, Beiert T, Jenniches I, Hansen J, Leidmaa E, Schrickel J, et al. Cannabinoid receptor 1 signalling modulates stress susceptibility and microglial responses to chronic social defeat stress. Transl Psychiatry. 2021;11:164 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 1a
Crespo M, González Terán B, Nikolic I, Mora A, Folgueira C, Rodriguez E, et al. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 7a
Malacco N, Souza J, Martins F, Rachid M, Simplicio J, Tirapelli C, et al. Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1
Rumfield C, Hyseni I, McBride J, Walker D, Fang R. Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection. Infect Immun. 2020;88: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4
Plemel J, Stratton J, Michaels N, Rawji K, Zhang E, Sinha S, et al. Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion. Sci Adv. 2020;6:eaay6324 pubmed publisher
  • flow cytometry; mouse; fig 2a
Yu M, Guo G, Huang L, Deng L, Chang C, Achyut B, et al. CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint. Nat Commun. 2020;11:515 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s3d
Pascual García M, Bonfill Teixidor E, Planas Rigol E, Rubio Perez C, Iurlaro R, Arias A, et al. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy. Nat Commun. 2019;10:2416 pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, et al. Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. Nat Commun. 2019;10:1801 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4
Casagrande F, de Souza Ferreira S, Nunes F, Romera L, Dos Santos S, Tessaro F, et al. Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs. J Diabetes Res. 2018;2018:6209694 pubmed publisher
  • flow cytometry; mouse
Bechelli J, Vergara L, Smalley C, Buzhdygan T, Bender S, Zhang W, et al. Atg5 Supports Rickettsia australis Infection in Macrophages In Vitro and In Vivo. Infect Immun. 2019;87: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Shi H, Han X, Sun Y, Shang C, Wei M, Ba X, et al. Chemokine (C-X-C motif) ligand 1 and CXCL2 produced by tumor promote the generation of monocytic myeloid-derived suppressor cells. Cancer Sci. 2018;109:3826-3839 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4a
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, et al. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. 2018;13:e0193737 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Montford J, Lehman A, Bauer C, Klawitter J, Klawitter J, Poczobutt J, et al. Bone marrow-derived cPLA2α contributes to renal fibrosis progression. J Lipid Res. 2018;59:380-390 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3a
Kwak J, Laskowski J, Li H, McSharry M, Sippel T, Bullock B, et al. Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression. Cancer Res. 2018;78:143-156 pubmed publisher
  • flow cytometry; mouse; loading ...; tbl s1
Kraakman M, Lee M, Al Sharea A, Dragoljevic D, Barrett T, Montenont E, et al. Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes. J Clin Invest. 2017;127:2133-2147 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Villa Bellosta R, Hamczyk M, Andres V. Novel phosphate-activated macrophages prevent ectopic calcification by increasing extracellular ATP and pyrophosphate. PLoS ONE. 2017;12:e0174998 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a, 3b
Fernandez N, Renna H, McHugh L, Mazolkova K, Crugnola W, Evans J. Mouse Mesenchymal Progenitor Cells Expressing Adipogenic and Osteogenic Transcription Factors Suppress the Macrophage Inflammatory Response. Stem Cells Int. 2017;2017:5846257 pubmed publisher
  • immunocytochemistry; human; fig 1b
Alvarez Carbonell D, Garcia Mesa Y, Milne S, Das B, Dobrowolski C, Rojas R, et al. Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells. Retrovirology. 2017;14:9 pubmed publisher
  • flow cytometry; mouse; fig S3
Lavender N, Yang J, Chen S, Sai J, Johnson C, Owens P, et al. The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo. BMC Cancer. 2017;17:88 pubmed publisher
  • flow cytometry; mouse; fig 2
Ikawa T, Masuda K, Endo T, Endo M, Isono K, Koseki Y, et al. Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program. Genes Dev. 2016;30:2475-2485 pubmed
  • flow cytometry; mouse; 1:100; fig s8
Monnerat G, Alarcón M, Vasconcellos L, Hochman Mendez C, Brasil G, Bassani R, et al. Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice. Nat Commun. 2016;7:13344 pubmed publisher
  • flow cytometry; mouse; fig 2
Raguz J, Jerić I, Niault T, Nowacka J, Kuzet S, Rupp C, et al. Epidermal RAF prevents allergic skin disease. elife. 2016;5: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Wu Y, Lan C, Ren D, Chen G. Induction of Siglec-1 by Endotoxin Tolerance Suppresses the Innate Immune Response by Promoting TGF-?1 Production. J Biol Chem. 2016;291:12370-82 pubmed publisher
  • flow cytometry; mouse; fig s1a
Rybtsov S, Ivanovs A, Zhao S, Medvinsky A. Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver. Development. 2016;143:1284-9 pubmed publisher
  • flow cytometry; mouse; fig 4
Fend L, Remy Ziller C, Foloppe J, Kempf J, Cochin S, Barraud L, et al. Oncolytic virotherapy with an armed vaccinia virus in an orthotopic model of renal carcinoma is associated with modification of the tumor microenvironment. Oncoimmunology. 2016;5:e1080414 pubmed
  • flow cytometry; mouse; 1:800; fig 2
Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed publisher
  • flow cytometry; mouse; fig s1
Kim D, Kim T, Wu G, Park B, Ha J, Kim Y, et al. Extracellular Release of CD11b by TLR9 Stimulation in Macrophages. PLoS ONE. 2016;11:e0150677 pubmed publisher
  • flow cytometry; mouse
Azpilikueta A, Agorreta J, Labiano S, Pérez Gracia J, Sánchez Paulete A, Aznar M, et al. Successful Immunotherapy against a Transplantable Mouse Squamous Lung Carcinoma with Anti-PD-1 and Anti-CD137 Monoclonal Antibodies. J Thorac Oncol. 2016;11:524-36 pubmed publisher
  • flow cytometry; mouse; loading ...; tbl 1
Goldberg G, Cornish A, Murphy J, Pang E, Lim L, Campbell I, et al. G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis. Am J Pathol. 2016;186:172-84 pubmed publisher
  • flow cytometry; mouse
Evans J, Salvador V, George S, Trevino Gutierrez C, Nunez C. Mouse aorta-derived mesenchymal progenitor cells contribute to and enhance the immune response of macrophage cells under inflammatory conditions. Stem Cell Res Ther. 2015;6:56 pubmed publisher
  • flow cytometry; mouse; fig 1
Johnson A, Costanzo A, Gareau M, Armando A, Quehenberger O, Jameson J, et al. High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PLoS ONE. 2015;10:e0122195 pubmed publisher
  • flow cytometry; mouse; fig 3
Dal Secco D, Wang J, Zeng Z, Kolaczkowska E, Wong C, Petri B, et al. A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury. J Exp Med. 2015;212:447-56 pubmed publisher
  • flow cytometry; mouse
Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed publisher
  • flow cytometry; mouse; 1:100; fig 1
Progatzky F, Sangha N, Yoshida N, McBrien M, Cheung J, Shia A, et al. Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation. Nat Commun. 2014;5:5864 pubmed publisher
  • flow cytometry; mouse
Zasłona Z, Przybranowski S, Wilke C, Van Rooijen N, Teitz Tennenbaum S, Osterholzer J, et al. Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma. J Immunol. 2014;193:4245-53 pubmed publisher
  • flow cytometry; mouse; fig 1
Hermida M, Doria P, Taguchi A, Mengel J, dos Santos W. Leishmania amazonensis infection impairs dendritic cell migration from the inflammatory site to the draining lymph node. BMC Infect Dis. 2014;14:450 pubmed publisher
  • flow cytometry; mouse; 1:50
Yang M, Rainone A, Shi X, Fournier S, Zhang J. A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome. Acta Neuropathol Commun. 2014;2:5 pubmed publisher
  • blocking or activating experiments; mouse
Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed publisher
Tomokatsu I, Masuda K, Huijskens M, Satoh R, Kakugawa K, Agata Y, et al. Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells. Stem Cell Reports. 2015;5:716-27 pubmed
Edgington Mitchell L, Rautela J, Duivenvoorden H, Jayatilleke K, van der Linden W, Verdoes M, et al. Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer. Oncotarget. 2015;6:27008-22 pubmed publisher
Xia F, Li R, Wang C, Yang S, Tian L, Dong H, et al. IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis. Sci Rep. 2013;3:1867 pubmed publisher
Welser Alves J, Crocker S, Milner R. A dual role for microglia in promoting tissue inhibitor of metalloproteinase (TIMP) expression in glial cells in response to neuroinflammatory stimuli. J Neuroinflammation. 2011;8:61 pubmed publisher
product information
Cat.# :
553310
Brand :
BD Pharmingen
Name :
CD11b
Format :
FITC
Clone :
M1/70
Isotype :
Rat IgG 2b
React :
Ms
Conc :
0.5 mg/ml
Apps :
FCM
Size :
0.5 mg
Status :
RUO
more info or order :
company information