product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
IFN
catalog :
551216
quantity :
1 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
R4-6A2
reactivity :
mouse
application :
ELISA, flow cytometry, blocking or activating experiments
more info or order :
citations: 43
Published Application/Species/Sample/DilutionReference
  • ELISA; mouse; 1:1000; loading ...; fig 2a
Kharkwal S, Johndrow C, Veerapen N, Kharkwal H, Saavedra Avila N, Carreño L, et al. Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T-cell Engagers Generates Antitumor Immunity While Avoiding Anergy. Cancer Res. 2021;81:1788-1801 pubmed publisher
  • ELISA; mouse; loading ...; fig 3a
Okuyama H, Tominaga A, Fukuoka S, Taguchi T, Kusumoto Y, Ono S. Spirulina lipopolysaccharides inhibit tumor growth in a Toll-like receptor 4-dependent manner by altering the cytokine milieu from interleukin-17/interleukin-23 to interferon-?. Oncol Rep. 2017;37:684-694 pubmed publisher
  • flow cytometry; mouse; 10 ug/ml; fig s8
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
  • blocking or activating experiments; mouse; 10 ug/ml; fig 2
Du C, Duan Y, Wei W, Cai Y, Chai H, Lv J, et al. Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination. Nat Commun. 2016;7:11120 pubmed publisher
  • ELISA; mouse; 1 ug/ml
Puntambekar S, Hinton D, Yin X, Savarin C, Bergmann C, Trapp B, et al. Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination. Glia. 2015;63:2106-2120 pubmed publisher
  • ELISA; mouse; 2,000 ug/ml
Burton B, Britton G, Fang H, Verhagen J, Smithers B, Sabatos Peyton C, et al. Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy. Nat Commun. 2014;5:4741 pubmed publisher
Jung H, Ku K, Kang B, Park J, Kim H, Kim K, et al. Intranasal delivery of an adenovirus-vector vaccine co-expressing a modified spike protein and a genetic adjuvant confers lasting mucosal immunity against SARS-CoV-2. Antiviral Res. 2023;216:105656 pubmed publisher
Kim Y, Kim K, Ko E, Kim M, Lee Y, Jung Y, et al. Complement C3 Plays a Key Role in Inducing Humoral and Cellular Immune Responses to Influenza Virus Strain-Specific Hemagglutinin-Based or Cross-Protective M2 Extracellular Domain-Based Vaccination. J Virol. 2018;92: pubmed publisher
Barik S, Miller M, Cattin Roy A, Ukah T, Zaghouani H. A distinct dendritic cell population arises in the thymus of IL-13Rα1-sufficient but not IL-13Rα1-deficient mice. Cell Immunol. 2018;331:130-136 pubmed publisher
Ogasawara T, Kohashi Y, Ikari J, Taniguchi T, Tsuruoka N, Watanabe Takano H, et al. Allergic TH2 Response Governed by B-Cell Lymphoma 6 Function in Naturally Occurring Memory Phenotype CD4+ T Cells. Front Immunol. 2018;9:750 pubmed publisher
Hwang M, Bergmann C. Alpha/Beta Interferon (IFN-?/?) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-?-Dependent Responses. J Virol. 2018;92: pubmed publisher
Madireddi S, Eun S, Mehta A, Birta A, Zajonc D, Niki T, et al. Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9. J Immunol. 2017;199:2721-2728 pubmed publisher
Barik S, Ellis J, Cascio J, Miller M, Ukah T, Cattin Roy A, et al. IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis. J Immunol. 2017;199:2236-2248 pubmed publisher
Li D, Ren Z. Cordyceps sinensis promotes immune regulation and enhances bacteriostatic activity of PA-824 via IL-10 in Mycobacterium tuberculosis disease. Braz J Med Biol Res. 2017;50:e6188 pubmed publisher
Klocke K, Holmdahl R, Wing K. CTLA-4 expressed by FOXP3+ regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis. Immunology. 2017;152:125-137 pubmed publisher
Bulla R, Tripodo C, Rami D, Ling G, Agostinis C, Guarnotta C, et al. C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation. Nat Commun. 2016;7:10346 pubmed publisher
Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, et al. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat Immunol. 2014;15:449-56 pubmed publisher
Chinnery F, King C, Elliott T, Bateman A, James E. Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk. Oncoimmunology. 2012;1:874-883 pubmed
Cardoso F, Roddick J, Groves P, Doolan D. Evaluation of approaches to identify the targets of cellular immunity on a proteome-wide scale. PLoS ONE. 2011;6:e27666 pubmed publisher
Löhning M, Hegazy A, Pinschewer D, Busse D, Lang K, Hofer T, et al. Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors. J Exp Med. 2008;205:53-61 pubmed publisher
Skokos D, Nussenzweig M. CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J Exp Med. 2007;204:1525-31 pubmed
Yu G, Xu X, Vu M, Kilpatrick E, Li X. NK cells promote transplant tolerance by killing donor antigen-presenting cells. J Exp Med. 2006;203:1851-8 pubmed
Boscardin S, Hafalla J, Masilamani R, Kamphorst A, Zebroski H, Rai U, et al. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J Exp Med. 2006;203:599-606 pubmed
Wilson M, Taylor M, Balic A, Finney C, Lamb J, Maizels R. Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J Exp Med. 2005;202:1199-212 pubmed
Jelley Gibbs D, Brown D, Dibble J, Haynes L, Eaton S, Swain S. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J Exp Med. 2005;202:697-706 pubmed
Yoneyama H, Matsuno K, Toda E, Nishiwaki T, Matsuo N, Nakano A, et al. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med. 2005;202:425-35 pubmed
Chakravarti S, Sabatos C, Xiao S, Illes Z, Cha E, Sobel R, et al. Tim-2 regulates T helper type 2 responses and autoimmunity. J Exp Med. 2005;202:437-44 pubmed
Shin T, Yoshimura K, Shin T, Crafton E, Tsuchiya H, Housseau F, et al. In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005;201:1531-41 pubmed
Grenningloh R, Kang B, Ho I. Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses. J Exp Med. 2005;201:615-26 pubmed
Khodoun M, Orekhova T, Potter C, Morris S, Finkelman F. Basophils initiate IL-4 production during a memory T-dependent response. J Exp Med. 2004;200:857-70 pubmed
Salama A, Chitnis T, Imitola J, Ansari M, Akiba H, Tushima F, et al. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med. 2003;198:71-8 pubmed
Sugita S, Streilein J. Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4. J Exp Med. 2003;198:161-71 pubmed
Jaeckel E, Klein L, Martin Orozco N, von Boehmer H. Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase. J Exp Med. 2003;197:1635-44 pubmed
Linton P, Bautista B, Biederman E, Bradley E, Harbertson J, Kondrack R, et al. Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo. J Exp Med. 2003;197:875-83 pubmed
Mauri C, Gray D, Mushtaq N, Londei M. Prevention of arthritis by interleukin 10-producing B cells. J Exp Med. 2003;197:489-501 pubmed
Vicari A, Chiodoni C, Vaure C, Ait Yahia S, Dercamp C, Matsos F, et al. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J Exp Med. 2002;196:541-9 pubmed
Helmby H, Takeda K, Akira S, Grencis R. Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13. J Exp Med. 2001;194:355-64 pubmed
Hogan R, Zhong W, Usherwood E, Cookenham T, Roberts A, Woodland D. Protection from respiratory virus infections can be mediated by antigen-specific CD4(+) T cells that persist in the lungs. J Exp Med. 2001;193:981-6 pubmed
Jember A, Zuberi R, Liu F, Croft M. Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J Exp Med. 2001;193:387-92 pubmed
Flaishon L, Hershkoviz R, Lantner F, Lider O, Alon R, Levo Y, et al. Autocrine secretion of interferon gamma negatively regulates homing of immature B cells. J Exp Med. 2000;192:1381-8 pubmed
Usherwood E, Roy D, Ward K, Surman S, Dutia B, Blackman M, et al. Control of gammaherpesvirus latency by latent antigen-specific CD8(+) T cells. J Exp Med. 2000;192:943-52 pubmed
van Hall T -, Sijts A, Camps M, Offringa R, Melief C, Kloetzel P, et al. Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28. J Exp Med. 2000;192:483-94 pubmed
d Ostiani C, Del Sero G, Bacci A, Montagnoli C, Spreca A, Mencacci A, et al. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans. Implications for initiation of T helper cell immunity in vitro and in vivo. J Exp Med. 2000;191:1661-74 pubmed
product information
Cat.# :
551216
Brand :
BD Pharmingen
Name :
IFN
Format :
Purified
Clone :
R4-6A2
Isotype :
Rat IgG 1
React :
Ms
Conc :
1.0 mg/ml
Apps :
ELISA Cap. , Neu
Size :
1 mg
Status :
RUO
more info or order :
company information