product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
p16 INK4
catalog :
551154
quantity :
150 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G175-405
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 1c
Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed publisher
  • western blot; human; fig 6
Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10; fig 4
  • western blot; human; fig 2
Chernova T, Sun X, Powley I, Galavotti S, Grosso S, Murphy F, et al. Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death Differ. 2016;23:1152-64 pubmed publisher
  • immunohistochemistry; human; 1:50; fig s4
Huebbers C, Adam A, Preuss S, Schiffer T, Schilder S, Guntinas Lichius O, et al. High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. Oncotarget. 2015;6:36172-84 pubmed publisher
  • western blot; human; 1:1000
Lee J, Garbe J, Vrba L, Miyano M, Futscher B, Stampfer M, et al. Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells. Front Cell Dev Biol. 2015;3:13 pubmed publisher
  • immunohistochemistry; human; fig S2
Garbe J, Vrba L, Sputova K, Fuchs L, Novak P, Brothman A, et al. Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Cell Cycle. 2014;13:3423-35 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 2
Egloff A, Lee J, Langer C, Quon H, Vaezi A, Grandis J, et al. Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: Eastern cooperative oncology group trial E3303. Clin Cancer Res. 2014;20:5041-51 pubmed publisher
  • immunohistochemistry - paraffin section; human
Huebbers C, Preuss S, Kolligs J, Vent J, Stenner M, Wieland U, et al. Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis. PLoS ONE. 2013;8:e57207 pubmed publisher
  • western blot; human
Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed publisher
Skalamera D, Stevenson A, Ehmann A, Ainger S, Lanagan C, Sturm R, et al. Melanoma mutations modify melanocyte dynamics in co-culture with keratinocytes or fibroblasts. J Cell Sci. 2019;132: pubmed publisher
Yano M, Shintani D, Katoh T, Hamada M, Ito K, Kozawa E, et al. Coexistence of endometrial mesonephric-like adenocarcinoma and endometrioid carcinoma suggests a Müllerian duct lineage: a case report. Diagn Pathol. 2019;14:54 pubmed publisher
Rosa E, Hurtado Puerto A, Falcão D, Brietzke A, de Almeida Prado Franceschi L, Cavalcanti Neto F, et al. Oral lichen planus and malignant transformation: The role of p16, Ki-67, Bub-3 and SOX4 in assessing precancerous potential. Exp Ther Med. 2018;15:4157-4166 pubmed publisher
Lang Kuhs K, Kreimer A, Trivedi S, Holzinger D, Pawlita M, Pfeiffer R, et al. Human papillomavirus 16 E6 antibodies are sensitive for human papillomavirus-driven oropharyngeal cancer and are associated with recurrence. Cancer. 2017;123:4382-4390 pubmed publisher
Ben Dayan M, Ow T, Belbin T, Wetzler J, Smith R, Childs G, et al. Nonpromoter methylation of the CDKN2A gene with active transcription is associated with improved locoregional control in laryngeal squamous cell carcinoma. Cancer Med. 2017;6:397-407 pubmed publisher
Robinson L, Jaing C, Pierce Campbell C, Magliocco A, Xiong Y, Magliocco G, et al. Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung. Br J Cancer. 2016;115:497-504 pubmed publisher
Hühns M, Simm G, Erbersdobler A, Zimpfer A. HPV Infection, but Not EBV or HHV-8 Infection, Is Associated with Salivary Gland Tumours. Biomed Res Int. 2015;2015:829349 pubmed publisher
Saglam O, Samayoa E, Somasekar S, Naccache S, Iwasaki A, Chiu C. No viral association found in a set of differentiated vulvar intraepithelial neoplasia cases by human papillomavirus and pan-viral microarray testing. PLoS ONE. 2015;10:e0125292 pubmed publisher
Pascoal Xavier M, Figueiredo A, Gomes L, Peruhype Magalhães V, Calzavara Silva C, Costa M, et al. RAP1 GTPase overexpression is associated with cervical intraepithelial neoplasia. PLoS ONE. 2015;10:e0123531 pubmed publisher
Schlecht N, Ben Dayan M, Anayannis N, Lleras R, Thomas C, Wang Y, et al. Epigenetic changes in the CDKN2A locus are associated with differential expression of P16INK4A and P14ARF in HPV-positive oropharyngeal squamous cell carcinoma. Cancer Med. 2015;4:342-53 pubmed publisher
Vosper J, Masuccio A, Kullmann M, Ploner C, Geley S, Hengst L. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation. Oncotarget. 2015;6:2889-902 pubmed
Lukesova E, Boucek J, Rotnáglová E, Salakova M, Koslabová E, Grega M, et al. High level of Tregs is a positive prognostic marker in patients with HPV-positive oral and oropharyngeal squamous cell carcinomas. Biomed Res Int. 2014;2014:303929 pubmed publisher
van Oosterwijk J, de Jong D, van Ruler M, Hogendoorn P, Dijkstra P, van Rijswijk C, et al. Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone. BMC Cancer. 2012;12:375 pubmed publisher
Teh M, Gemenetzidis E, Patel D, Tariq R, Nadir A, Bahta A, et al. FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma. PLoS ONE. 2012;7:e34329 pubmed publisher
Siddiqi S, Terry M, Matushansky I. Hiwi mediated tumorigenesis is associated with DNA hypermethylation. PLoS ONE. 2012;7:e33711 pubmed publisher
Merkley M, Hildebrandt E, Podolsky R, Arnouk H, Ferris D, Dynan W, et al. Large-scale analysis of protein expression changes in human keratinocytes immortalized by human papilloma virus type 16 E6 and E7 oncogenes. Proteome Sci. 2009;7:29 pubmed publisher
product information
Cat.# :
551154
Brand :
BD Pharmingen
Name :
p16 INK4
Format :
Purified
Clone :
G175-405
Isotype :
Ms IgG 1
React :
Hu
Apps :
IHC(Fr) , IHC(P) , IP , WB
Size :
150 µg
Status :
RUO
more info or order :
company information