product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
MLH1
catalog :
551092
quantity :
150 µg
price :
340.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G168-15
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; loading ...; fig 4f
Pan H, Jiang N, Sun S, Jiang H, Xu J, Jiang X, et al. UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I. Cell Death Dis. 2020;11:142 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 4i
Zhang Q, Ji S, Busayavalasa K, Yu C. SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. Sci Adv. 2019;5:eaau9780 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10; loading ...; fig 1
Huang C, Huang S, Chien C, Lee H, Yang S, Chang C, et al. Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation. Oncol Lett. 2016;12:4427-4434 pubmed publisher
  • immunocytochemistry; mouse; 1:50
Li M, Cole F, Patel D, Misenko S, Her J, Malhowski A, et al. 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. EMBO Rep. 2016;17:1532-1541 pubmed
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 1
Takahashi S, Kohashi K, Yamamoto H, Hirahashi M, Kumagai R, Takizawa N, et al. Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum. Hum Pathol. 2015;46:1257-66 pubmed publisher
  • immunohistochemistry; human; 1:50
Geels Y, van der Putten L, van Tilborg A, Lurkin I, Zwarthoff E, Pijnenborg J, et al. Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium. Gynecol Oncol. 2015;137:245-51 pubmed publisher
  • immunohistochemistry; human; 1:25; loading ...
Boulagnon C, Dudez O, Beaudoux O, Dalstein V, Kianmanesh R, Bouché O, et al. BRAFV600E Gene Mutation in Colonic Adenocarcinomas. Immunohistochemical Detection Using Tissue Microarray and Clinicopathologic Characteristics: An 86 Case Series. Appl Immunohistochem Mol Morphol. 2016;24:88-96 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 3
Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, et al. A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis. 2015;6:e1610 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Koppensteiner R, Samartzis E, Noske A, von Teichman A, Dedes I, Gwerder M, et al. Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro. PLoS ONE. 2014;9:e100041 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:30
Baiocchi G, Portolani N, Vermi W, Baronchelli C, Gheza F, Zogno C, et al. Lynch syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old. BMC Surg. 2014;14:9 pubmed publisher
  • immunohistochemistry; human
Malesci A, Basso G, Bianchi P, Fini L, Grizzi F, Celesti G, et al. Molecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasia. Br J Cancer. 2014;110:1228-35 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Boulagnon C, Jazeron J, Diaz Cives A, Ehrhard F, Bouche O, Diebold M. Filiform polyposis: A benign entity? Case report and literature review. Pathol Res Pract. 2014;210:189-93 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:30; tbl 1
Egoavil C, Alenda C, Castillejo A, Paya A, Peiro G, Sanchez Heras A, et al. Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers. PLoS ONE. 2013;8:e79737 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25
Donada M, Bonin S, Barbazza R, Pettirosso D, Stanta G. Management of stage II colon cancer - the use of molecular biomarkers for adjuvant therapy decision. BMC Gastroenterol. 2013;13:36 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Link J, Jahn D, Schmitt J, Göb E, Baar J, Ortega S, et al. The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse. PLoS Genet. 2013;9:e1003261 pubmed publisher
  • immunocytochemistry; mouse; 1:50
Takada Y, Isono K, Shinga J, Turner J, Kitamura H, Ohara O, et al. Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development. 2007;134:579-90 pubmed
Goeppert B, Roessler S, Renner M, Loeffler M, Singer S, Rausch M, et al. Low frequency of mismatch repair deficiency in gallbladder cancer. Diagn Pathol. 2019;14:36 pubmed publisher
Goeppert B, Roessler S, Renner M, Singer S, Mehrabi A, Vogel M, et al. Mismatch repair deficiency is a rare but putative therapeutically relevant finding in non-liver fluke associated cholangiocarcinoma. Br J Cancer. 2019;120:109-114 pubmed publisher
Lin Z, Liu J, Peng L, Zhang D, Jin M, Wang J, et al. Complete pathological response following neoadjuvant FOLFOX chemotherapy in BRCA2-mutant locally advanced rectal cancer: a case report. BMC Cancer. 2018;18:1253 pubmed publisher
Wang H, Yuan Q, Niu M, Zhang W, Wen L, Fu H, et al. Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice. Cell Death Dis. 2018;9:76 pubmed publisher
Valtcheva N, Lang F, Noske A, Samartzis E, Schmidt A, Bellini E, et al. Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing - a case report. BMC Cancer. 2017;17:66 pubmed publisher
Brandt S, Samartzis E, Zimmermann A, Fink D, Moch H, Noske A, et al. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer. BMC Cancer. 2017;17:44 pubmed publisher
Vlenterie M, Hillebrandt Roeffen M, Flucke U, Groenen P, Tops B, Kamping E, et al. Next generation sequencing in synovial sarcoma reveals novel gene mutations. Oncotarget. 2015;6:34680-90 pubmed publisher
Smagulova F, Brick K, Pu Y, Sengupta U, Camerini Otero R, Petukhova G. Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics. 2013;14:493 pubmed publisher
Levidou G, Saetta A, Gigelou F, Karlou M, Papanastasiou P, Stamatelli A, et al. ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics. World J Surg Oncol. 2012;10:47 pubmed publisher
Jensen S, Vainer B, Kruhøffer M, Sørensen J. Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression. BMC Cancer. 2009;9:25 pubmed publisher
Kolas N, Svetlanov A, Lenzi M, Macaluso F, Lipkin S, Liskay R, et al. Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I. J Cell Biol. 2005;171:447-58 pubmed
Sasiadek M, Stembalska Kozlowska A, Smigiel R, Ramsey D, Kayademir T, Blin N. Impairment of MLH1 and CDKN2A in oncogenesis of laryngeal cancer. Br J Cancer. 2004;90:1594-9 pubmed
product information
Cat.# :
551092
Brand :
BD Pharmingen
Name :
MLH1
Format :
Purified
Clone :
G168-15
Isotype :
Ms IgG 1
React :
Hu
Apps :
IHC(Fr) , IHC(P) , WB
Size :
150 µg
Status :
RUO
List Price :
340.00 USD
more info or order :
company information