product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
MLH1
catalog :
551091
quantity :
50 µg
price :
210.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G168-15
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; 1:250; loading ...; fig 5b
Hung S, Saiakhova A, Faber Z, Bartels C, Neu D, Bayles I, et al. Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes. elife. 2019;8: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10; loading ...; fig 1
Huang C, Huang S, Chien C, Lee H, Yang S, Chang C, et al. Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation. Oncol Lett. 2016;12:4427-4434 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 3
Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja J, et al. Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope. Nat Commun. 2016;7:11084 pubmed publisher
  • immunohistochemistry; human; 1:25; loading ...
Boulagnon C, Dudez O, Beaudoux O, Dalstein V, Kianmanesh R, Bouché O, et al. BRAFV600E Gene Mutation in Colonic Adenocarcinomas. Immunohistochemical Detection Using Tissue Microarray and Clinicopathologic Characteristics: An 86 Case Series. Appl Immunohistochem Mol Morphol. 2016;24:88-96 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 1
Takahashi S, Kohashi K, Yamamoto H, Hirahashi M, Kumagai R, Takizawa N, et al. Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum. Hum Pathol. 2015;46:1257-66 pubmed publisher
  • immunohistochemistry; human; 1:50
Geels Y, van der Putten L, van Tilborg A, Lurkin I, Zwarthoff E, Pijnenborg J, et al. Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium. Gynecol Oncol. 2015;137:245-51 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Koppensteiner R, Samartzis E, Noske A, von Teichman A, Dedes I, Gwerder M, et al. Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro. PLoS ONE. 2014;9:e100041 pubmed publisher
  • immunohistochemistry; human
Malesci A, Basso G, Bianchi P, Fini L, Grizzi F, Celesti G, et al. Molecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasia. Br J Cancer. 2014;110:1228-35 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
Boulagnon C, Jazeron J, Diaz Cives A, Ehrhard F, Bouche O, Diebold M. Filiform polyposis: A benign entity? Case report and literature review. Pathol Res Pract. 2014;210:189-93 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:30; tbl 1
Egoavil C, Alenda C, Castillejo A, Paya A, Peiro G, Sanchez Heras A, et al. Prevalence of Lynch syndrome among patients with newly diagnosed endometrial cancers. PLoS ONE. 2013;8:e79737 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25
Donada M, Bonin S, Barbazza R, Pettirosso D, Stanta G. Management of stage II colon cancer - the use of molecular biomarkers for adjuvant therapy decision. BMC Gastroenterol. 2013;13:36 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Link J, Jahn D, Schmitt J, Göb E, Baar J, Ortega S, et al. The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse. PLoS Genet. 2013;9:e1003261 pubmed publisher
  • immunocytochemistry; mouse; 1:50
Takada Y, Isono K, Shinga J, Turner J, Kitamura H, Ohara O, et al. Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development. 2007;134:579-90 pubmed
Bailis J, Gordon M, Gurgel J, Komor A, Barton J, Kirsch I. An inducible, isogenic cancer cell line system for targeting the state of mismatch repair deficiency. PLoS ONE. 2013;8:e78726 pubmed publisher
von Bueren A, Bacolod M, Hagel C, Heinimann K, Fedier A, Kordes U, et al. Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours. Br J Cancer. 2012;107:1399-408 pubmed publisher
An J, Kim E, Zakrzewska A, Yoo Y, Jang J, Han D, et al. UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells. PLoS ONE. 2012;7:e37414 pubmed publisher
Levidou G, Saetta A, Gigelou F, Karlou M, Papanastasiou P, Stamatelli A, et al. ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics. World J Surg Oncol. 2012;10:47 pubmed publisher
Schramm S, Fraune J, Naumann R, Hernández Hernández A, Hoog C, Cooke H, et al. A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility. PLoS Genet. 2011;7:e1002088 pubmed publisher
Jensen S, Vainer B, Kruhøffer M, Sørensen J. Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression. BMC Cancer. 2009;9:25 pubmed publisher
de la Fuente R, Parra M, Viera A, Calvente A, Gómez R, Suja J, et al. Meiotic pairing and segregation of achiasmate sex chromosomes in eutherian mammals: the role of SYCP3 protein. PLoS Genet. 2007;3:e198 pubmed
Pruitt K, Zinn R, Ohm J, McGarvey K, Kang S, Watkins D, et al. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2006;2:e40 pubmed
Kolas N, Svetlanov A, Lenzi M, Macaluso F, Lipkin S, Liskay R, et al. Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I. J Cell Biol. 2005;171:447-58 pubmed
Sasiadek M, Stembalska Kozlowska A, Smigiel R, Ramsey D, Kayademir T, Blin N. Impairment of MLH1 and CDKN2A in oncogenesis of laryngeal cancer. Br J Cancer. 2004;90:1594-9 pubmed
product information
Cat.# :
551091
Brand :
BD Pharmingen
Name :
MLH1
Format :
Purified
Clone :
G168-15
Isotype :
Ms IgG 1
React :
Hu
Apps :
IHC(Fr) , IHC(P) , WB
Size :
50 µg
Status :
RUO
List Price :
210.00 USD
more info or order :
company information