product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
p16 INK4
catalog :
550834
quantity :
1 mL
price :
172.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
G175-405
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2d
Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu F, et al. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis. PLoS Biol. 2019;17:e3000201 pubmed publisher
  • western blot; human; 1:200; fig 6
Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS ONE. 2016;11:e0154531 pubmed publisher
  • western blot; human; fig 4
Strickland S, Vande Pol S. The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. J Virol. 2016;90:5611-5621 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:10; fig 4
  • western blot; human; fig 2
Chernova T, Sun X, Powley I, Galavotti S, Grosso S, Murphy F, et al. Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death Differ. 2016;23:1152-64 pubmed publisher
  • flow cytometry; human; 1:50; loading ...; fig st3
  • western blot; human; 1:500; loading ...; fig 1c
Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed publisher
  • immunohistochemistry; human; 1:50; fig s4
Huebbers C, Adam A, Preuss S, Schiffer T, Schilder S, Guntinas Lichius O, et al. High glucose uptake unexpectedly is accompanied by high levels of the mitochondrial ß-F1-ATPase subunit in head and neck squamous cell carcinoma. Oncotarget. 2015;6:36172-84 pubmed publisher
  • immunohistochemistry; human; fig S2
Garbe J, Vrba L, Sputova K, Fuchs L, Novak P, Brothman A, et al. Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations. Cell Cycle. 2014;13:3423-35 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 2
Egloff A, Lee J, Langer C, Quon H, Vaezi A, Grandis J, et al. Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: Eastern cooperative oncology group trial E3303. Clin Cancer Res. 2014;20:5041-51 pubmed publisher
  • immunohistochemistry - paraffin section; human
Huebbers C, Preuss S, Kolligs J, Vent J, Stenner M, Wieland U, et al. Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis. PLoS ONE. 2013;8:e57207 pubmed publisher
  • western blot; human
Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed publisher
Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, et al. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. Nat Commun. 2019;10:3329 pubmed publisher
Yano M, Shintani D, Katoh T, Hamada M, Ito K, Kozawa E, et al. Coexistence of endometrial mesonephric-like adenocarcinoma and endometrioid carcinoma suggests a Müllerian duct lineage: a case report. Diagn Pathol. 2019;14:54 pubmed publisher
Rosa E, Hurtado Puerto A, Falcão D, Brietzke A, de Almeida Prado Franceschi L, Cavalcanti Neto F, et al. Oral lichen planus and malignant transformation: The role of p16, Ki-67, Bub-3 and SOX4 in assessing precancerous potential. Exp Ther Med. 2018;15:4157-4166 pubmed publisher
Lang Kuhs K, Kreimer A, Trivedi S, Holzinger D, Pawlita M, Pfeiffer R, et al. Human papillomavirus 16 E6 antibodies are sensitive for human papillomavirus-driven oropharyngeal cancer and are associated with recurrence. Cancer. 2017;123:4382-4390 pubmed publisher
Hühns M, Simm G, Erbersdobler A, Zimpfer A. HPV Infection, but Not EBV or HHV-8 Infection, Is Associated with Salivary Gland Tumours. Biomed Res Int. 2015;2015:829349 pubmed publisher
Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int. 2015;2015:731938 pubmed publisher
Vosper J, Masuccio A, Kullmann M, Ploner C, Geley S, Hengst L. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation. Oncotarget. 2015;6:2889-902 pubmed
Marthandan S, Priebe S, Hemmerich P, Klement K, Diekmann S. Long-term quiescent fibroblast cells transit into senescence. PLoS ONE. 2014;9:e115597 pubmed publisher
Lukesova E, Boucek J, Rotnáglová E, Salakova M, Koslabová E, Grega M, et al. High level of Tregs is a positive prognostic marker in patients with HPV-positive oral and oropharyngeal squamous cell carcinomas. Biomed Res Int. 2014;2014:303929 pubmed publisher
van Oosterwijk J, de Jong D, van Ruler M, Hogendoorn P, Dijkstra P, van Rijswijk C, et al. Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone. BMC Cancer. 2012;12:375 pubmed publisher
Siddiqi S, Terry M, Matushansky I. Hiwi mediated tumorigenesis is associated with DNA hypermethylation. PLoS ONE. 2012;7:e33711 pubmed publisher
Merkley M, Hildebrandt E, Podolsky R, Arnouk H, Ferris D, Dynan W, et al. Large-scale analysis of protein expression changes in human keratinocytes immortalized by human papilloma virus type 16 E6 and E7 oncogenes. Proteome Sci. 2009;7:29 pubmed publisher
product information
Cat.# :
550834
Brand :
BD Pharmingen
Name :
p16 INK4
Format :
Purified
Clone :
G175-405
Isotype :
Ms IgG 1
React :
Hu
Conc :
31.25 µg/ml
Apps :
IHC(F)* , IHC(Fr) , WB
Size :
1 mL
Status :
RUO
List Price :
172.00 USD
more info or order :
company information