product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Panendothelial Cell Antigen
catalog :
550563
quantity :
1 mL
price :
152.00 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MECA-32
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig 1c
Aguilera T, Rafat M, Castellini L, Shehade H, Kariolis M, Hui A, et al. Reprogramming the immunological microenvironment through radiation and targeting Axl. Nat Commun. 2016;7:13898 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig st2
Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, et al. Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016;538:392-396 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 9c
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 3b
Leuci V, Maione F, Rotolo R, Giraudo E, Sassi F, Migliardi G, et al. Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity. J Transl Med. 2016;14:119 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1j
Johnson V, Xiang M, Chen Z, Junge H. Neurite Mistargeting and Inverse Order of Intraretinal Vascular Plexus Formation Precede Subretinal Vascularization in Vldlr Mutant Mice. PLoS ONE. 2015;10:e0132013 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3a
Brindle N, Joyce J, Rostker F, Lawlor E, Swigart Brown L, Evan G, et al. Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer. PLoS ONE. 2015;10:e0120348 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 2d
Maione F, Oliaro Bosso S, Meda C, Di Nicolantonio F, Bussolino F, Balliano G, et al. The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination. Sci Rep. 2015;5:9054 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 2
Maione F, Giraudo E. Tumor angiogenesis: methods to analyze tumor vasculature and vessel normalization in mouse models of cancer. Methods Mol Biol. 2015;1267:349-65 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Pickup M, Hover L, Polikowsky E, Chytil A, Gorska A, Novitskiy S, et al. BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation. Mol Oncol. 2015;9:179-91 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Owens P, Pickup M, Novitskiy S, Giltnane J, Gorska A, Hopkins C, et al. Inhibition of BMP signaling suppresses metastasis in mammary cancer. Oncogene. 2015;34:2437-49 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Kühnisch J, Seto J, Lange C, Stumpp S, Kobus K, Grohmann J, et al. Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models. Bone. 2014;66:155-62 pubmed publisher
  • immunohistochemistry - frozen section; mouse
He L, Marneros A. Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar. Am J Pathol. 2013;182:2407-17 pubmed publisher
Cho C, Wang Y, Smallwood P, Williams J, Nathans J. Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers. elife. 2019;8: pubmed publisher
Noy P, Gavin R, Colombo D, Haining E, Reyat J, Payne H, et al. Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells. Haematologica. 2018;: pubmed publisher
Pitarresi J, Liu X, Avendano A, Thies K, Sizemore G, Hammer A, et al. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Sci Alliance. 2018;1:e201800190 pubmed publisher
Oladipupo S, Kabir A, Smith C, Choi K, Ornitz D. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep. 2018;8:14724 pubmed publisher
Halder S, Kant R, Milner R. Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels. Acta Neuropathol Commun. 2018;6:86 pubmed publisher
Pi L, Fu C, Lu Y, Zhou J, Jorgensen M, Shenoy V, et al. Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension. Front Physiol. 2018;9:138 pubmed publisher
Roudnicky F, Yoon S, Poghosyan S, Schwager S, Poyet C, Vella G, et al. Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels. Oncogene. 2018;37:2573-2585 pubmed publisher
Kortlever R, Sodir N, Wilson C, Burkhart D, Pellegrinet L, Brown Swigart L, et al. Myc Cooperates with Ras by Programming Inflammation and Immune Suppression. Cell. 2017;171:1301-1315.e14 pubmed publisher
Guo H, Kazadaeva Y, Ortega F, Manjunath N, Desai T. Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017;430:214-223 pubmed publisher
Zhang C, Lai M, Khandan L, Lee L, Chen Z, Junge H. Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function. Nat Commun. 2017;8:16050 pubmed publisher
Kühnisch J, Seto J, Lange C, Schrof S, Stumpp S, Kobus K, et al. Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1. PLoS ONE. 2014;9:e86115 pubmed publisher
Sims Lucas S, Schaefer C, Bushnell D, Ho J, Logar A, Prochownik E, et al. Endothelial Progenitors Exist within the Kidney and Lung Mesenchyme. PLoS ONE. 2013;8:e65993 pubmed publisher
Kümin A, Schafer M, Epp N, Bugnon P, Born Berclaz C, Oxenius A, et al. Peroxiredoxin 6 is required for blood vessel integrity in wounded skin. J Cell Biol. 2007;179:747-60 pubmed
Chavakis E, Aicher A, Heeschen C, Sasaki K, Kaiser R, El Makhfi N, et al. Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells. J Exp Med. 2005;201:63-72 pubmed
Ibe S, Qin Z, Schuler T, Preiss S, Blankenstein T. Tumor rejection by disturbing tumor stroma cell interactions. J Exp Med. 2001;194:1549-59 pubmed
product information
Cat.# :
550563
Brand :
BD Pharmingen
Name :
Panendothelial Cell Antigen
Format :
Purified
Clone :
MECA-32
Isotype :
Rat IgG 2a
React :
Ms
Conc :
31.25 µg/ml
Apps :
FCM , IHC(Fr
Size :
1 mL
Status :
RUO
List Price :
152.00 USD
more info or order :
company information