product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
Caspase-3, Active Form
catalog :
550557
quantity :
100 Tests
price :
330.00 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C92-605
reactivity :
crab eating macaque, human, mouse, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, blocking or activating experiments
more info or order :
citations: 41
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 5c
Matsuda K, Kobayakawa T, Tsuchiya K, Hattori S, Nomura W, Gatanaga H, et al. Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal. J Biol Chem. 2019;294:116-129 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Khan A, Carpenter B, Santos e Sousa P, Pospori C, Khorshed R, Griffin J, et al. Redirection to the bone marrow improves T cell persistence and antitumor functions. J Clin Invest. 2018;128:2010-2024 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 4b
Mayer C, Gazumyan A, Kara E, Gitlin A, Golijanin J, Viant C, et al. The microanatomic segregation of selection by apoptosis in the germinal center. Science. 2017;358: pubmed publisher
  • flow cytometry; crab eating macaque; loading ...; fig 5d
Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3f
Engler J, Kursawe N, Solano M, Patas K, Wehrmann S, Heckmann N, et al. Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy. Proc Natl Acad Sci U S A. 2017;114:E181-E190 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
Cheng H, Gaddis D, Wu R, McSkimming C, Haynes L, Taylor A, et al. Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. J Clin Invest. 2016;126:3236-46 pubmed publisher
  • flow cytometry; human; loading ...; fig s3b
Gren S, Janciauskiene S, Sandeep S, Jonigk D, Kvist P, Gerwien J, et al. The protease inhibitor cystatin C down-regulates the release of IL-? and TNF-? in lipopolysaccharide activated monocytes. J Leukoc Biol. 2016;100:811-822 pubmed
  • flow cytometry; human; loading ...; fig 5e
Carrasco A, Fernández Bañares F, Pedrosa E, Salas A, Loras C, Rosinach M, et al. Regional Specialisation of T Cell Subsets and Apoptosis in the Human Gut Mucosa: Differences Between Ileum and Colon in Healthy Intestine and Inflammatory Bowel Diseases. J Crohns Colitis. 2016;10:1042-54 pubmed publisher
  • flow cytometry; mouse; fig 5a
Andzinski L, Kasnitz N, Stahnke S, Wu C, Gereke M, von Köckritz Blickwede M, et al. Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int J Cancer. 2016;138:1982-93 pubmed publisher
  • flow cytometry; mouse; fig s9a
Weigelin B, Bolaños E, Teijeira A, Martinez Forero I, Labiano S, Azpilikueta A, et al. Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb. Proc Natl Acad Sci U S A. 2015;112:7551-6 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, et al. Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this. Development. 2014;141:3319-23 pubmed publisher
  • immunohistochemistry; zebrafish
Balci T, Prykhozhij S, Teh E, Da as S, McBride E, Liwski R, et al. A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis. Br J Haematol. 2014;167:48-61 pubmed publisher
  • western blot; human
Wang X, Stafford W, Mazurkiewicz M, Fryknäs M, Brjnic S, Zhang X, et al. The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death. Mol Pharmacol. 2014;85:932-45 pubmed publisher
  • western blot; human; fig 4
Xargay Torrent S, Lopez Guerra M, Saborit Villarroya I, Rosich L, Campo E, Roué G, et al. Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters. Clin Cancer Res. 2011;17:3956-68 pubmed publisher
  • immunohistochemistry - paraffin section; human
Koschny R, Ganten T, Sykora J, Haas T, Sprick M, Kolb A, et al. TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. Hepatology. 2007;45:649-58 pubmed
Mintz M, Felce J, Chou M, Mayya V, Xu Y, Shui J, et al. The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis. Immunity. 2019;: pubmed publisher
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
Silva H, Bafica A, Rodrigues Luiz G, Chi J, Santos P, Reis B, et al. Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges. J Exp Med. 2019;216:786-806 pubmed publisher
Siekierska A, Stamberger H, Deconinck T, Oprescu S, Partoens M, Zhang Y, et al. Biallelic VARS variants cause developmental encephalopathy with microcephaly that is recapitulated in vars knockout zebrafish. Nat Commun. 2019;10:708 pubmed publisher
Chea L, Wyatt L, Gangadhara S, Moss B, Amara R. Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13R Delays Apoptosis and Enhances Humoral Responses. J Virol. 2019;93: pubmed publisher
Kennedy J, Steain M, Slobedman B, Abendroth A. Infection and Functional Modulation of Human Monocytes and Macrophages by Varicella-Zoster Virus. J Virol. 2019;93: pubmed publisher
Hattori S, Matsuda K, Tsuchiya K, Gatanaga H, Oka S, Yoshimura K, et al. Combination of a Latency-Reversing Agent With a Smac Mimetic Minimizes Secondary HIV-1 Infection in vitro. Front Microbiol. 2018;9:2022 pubmed publisher
Robinson C, Chong A, Ashbrook A, Jeng G, Jin J, Chen H, et al. Male germ cells support long-term propagation of Zika virus. Nat Commun. 2018;9:2090 pubmed publisher
Feng L, Vujicic S, Dietrich M, Litbarg N, Setty S, Antoni A, et al. Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis. J Biol Chem. 2018;293:10245-10263 pubmed publisher
Varelias A, Bunting M, Ormerod K, Koyama M, Olver S, Straube J, et al. Recipient mucosal-associated invariant T cells control GVHD within the colon. J Clin Invest. 2018;128:1919-1936 pubmed publisher
Zhang Y, Tech L, George L, Acs A, Durrett R, Hess H, et al. Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells. J Exp Med. 2018;215:1227-1243 pubmed publisher
Filipova D, Henry M, Rotshteyn T, Brunn A, Carstov M, Deckert M, et al. Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5. PLoS ONE. 2018;13:e0194428 pubmed publisher
Clarke A, Riffelmacher T, Braas D, Cornall R, Simon A. B1a B cells require autophagy for metabolic homeostasis and self-renewal. J Exp Med. 2018;215:399-413 pubmed publisher
Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed publisher
Wonderlich E, Caroline A, McMillen C, Walters A, Reed D, Barratt Boyes S, et al. Peripheral Blood Biomarkers of Disease Outcome in a Monkey Model of Rift Valley Fever Encephalitis. J Virol. 2018;92: pubmed publisher
Wasiuk A, Testa J, Weidlick J, Sisson C, Vitale L, Widger J, et al. CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy. J Immunol. 2017;199:4110-4123 pubmed publisher
Swan Z, Bouwer A, Wonderlich E, Barratt Boyes S. Persistent accumulation of gut macrophages with impaired phagocytic function correlates with SIV disease progression in macaques. Eur J Immunol. 2017;47:1925-1935 pubmed publisher
Woodberry T, Loughland J, Minigo G, Burel J, Amante F, Piera K, et al. Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation. Infect Immun. 2017;85: pubmed publisher
Kim N, Cha Y, Lee J, Lee S, Yang J, Yun J, et al. Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress. Nat Commun. 2017;8:14374 pubmed publisher
Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R. Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation. Mol Biol Cell. 2017;28:834-842 pubmed publisher
Cheng L, Ma J, Li J, Li D, Li G, Li F, et al. Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. J Clin Invest. 2017;127:269-279 pubmed publisher
Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed publisher
Tousif S, Singh D, Ahmad S, Moodley P, Bhattacharyya M, Van Kaer L, et al. Isoniazid induces apoptosis of activated CD4+ T cells: implications for post-therapy tuberculosis reactivation and reinfection. J Biol Chem. 2014;289:30190-5 pubmed publisher
Das G, Choi Y, Sicinski P, Levine E. Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells. Neural Dev. 2009;4:15 pubmed publisher
Meyer Bahlburg A, Andrews S, Yu K, Porcelli S, Rawlings D. Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med. 2008;205:155-68 pubmed publisher
Pardo J, Urban C, Galvez E, Ekert P, Muller U, Kwon Chung J, et al. The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice. J Cell Biol. 2006;174:509-19 pubmed
product information
Cat.# :
550557
Brand :
BD Pharmingen
Name :
Caspase-3, Active Form
Format :
Biotin
Clone :
C92-605
Isotype :
Rab IgG
React :
Hu , Ms
Apps :
IC/FCM
Size :
100 Tests
Status :
RUO
List Price :
330.00 USD
more info or order :
company information