Published Application/Species/Sample/Dilution | Reference |
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- mass cytometry; mouse; loading ...; fig s3
| Lagnado A, Leslie J, Ruchaud Sparagano M, Victorelli S, Hirsova P, Ogrodnik M, et al. Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner. EMBO J. 2021;40:e106048 pubmed publisher
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- immunohistochemistry; human; 1:200; loading ...
| Dabelsteen S, Pallesen E, Marinova I, Nielsen M, Adamopoulou M, Rømer T, et al. Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model. Dev Cell. 2020;54:669-684.e7 pubmed publisher
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- immunocytochemistry; human; fig 5i
| Bae H, Hong K, Lee C, Jang C, Lee S, Choe K, et al. Angiopoietin-2-integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance. Nat Commun. 2020;11:2980 pubmed publisher
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- immunocytochemistry; mouse; 1:50; fig 5a
| Albrengues J, Shields M, Ng D, Park C, Ambrico A, Poindexter M, et al. Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science. 2018;361: pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:100; fig 8a
| Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig s2
| Yu W, Hill W, Robson S, Zeidel M. Role of P2X4 Receptor in Mouse Voiding Function. Sci Rep. 2018;8:1838 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:100
- flow cytometry; mouse; 1:50; loading ...; fig 1c
| Peuhu E, Salomaa S, De Franceschi N, Potter C, Sundberg J, Pouwels J. Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice. PLoS ONE. 2017;12:e0186628 pubmed publisher
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- immunocytochemistry; human; fig 6b
| Lin Y, Ohbayashi N, Hongu T, Katagiri N, Funakoshi Y, Lee H, et al. Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration. Sci Rep. 2017;7:11431 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 1d
| Georgiadou M, Lilja J, Jacquemet G, Guzmán C, Rafaeva M, Alibert C, et al. AMPK negatively regulates tensin-dependent integrin activity. J Cell Biol. 2017;216:1107-1121 pubmed publisher
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- immunocytochemistry; mouse; 1:200; fig 1a
- immunohistochemistry; mouse; 1:200; loading ...; fig s9b
| Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
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- flow cytometry; mouse; 1:50; fig s3
- immunocytochemistry; human; fig 3
| Barrow McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche B, et al. Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun. 2016;7:11942 pubmed publisher
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- immunocytochemistry; human; 1:250; fig 3
| Petridou N, Skourides P. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016;7:10899 pubmed publisher
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- immunocytochemistry; human; fig 4
| Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher
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- flow cytometry; mouse; 1:200; fig 2s2
- immunocytochemistry; mouse; 1:200; fig 3
| Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed publisher
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- immunohistochemistry; mouse; 1:25; fig 6
| Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
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- flow cytometry; human; 1:200; fig 4
- immunocytochemistry; human; 1:200; fig 4
| Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed publisher
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- immunocytochemistry; hamsters; fig 3a
- immunocytochemistry; mouse; fig 1c
| Yu C, Rafiq N, Cao F, Zhou Y, Krishnasamy A, Biswas K, et al. Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force. Nat Commun. 2015;6:8672 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:10
- immunocytochemistry; mouse; 0.5 ug/ml
| Zhu Y, Matsumoto T, Nagasawa T, Mackay F, Murakami F. Chemokine Signaling Controls Integrity of Radial Glial Scaffold in Developing Spinal Cord and Consequential Proper Position of Boundary Cap Cells. J Neurosci. 2015;35:9211-24 pubmed publisher
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- flow cytometry; mouse; 1:100
| Lujan E, Zunder E, Ng Y, Goronzy I, Nolan G, Wernig M. Early reprogramming regulators identified by prospective isolation and mass cytometry. Nature. 2015;521:352-6 pubmed publisher
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- immunohistochemistry - paraffin section; mouse
- western blot; mouse
| Saito K, Fukumoto E, Yamada A, Yuasa K, Yoshizaki K, Iwamoto T, et al. Interaction between fibronectin and β1 integrin is essential for tooth development. PLoS ONE. 2015;10:e0121667 pubmed publisher
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- flow cytometry; mouse; fig 5
| Sugahara K, Braun G, de Mendoza T, Kotamraju V, French R, Lowy A, et al. Tumor-penetrating iRGD peptide inhibits metastasis. Mol Cancer Ther. 2015;14:120-8 pubmed publisher
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- blocking or activating experiments; mouse
| Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood D, Schwartz M, et al. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. J Biol Chem. 2015;290:409-22 pubmed publisher
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- immunohistochemistry; mouse; 1:50
| Pelton J, Wright C, Leitges M, Bautch V. Multiple endothelial cells constitute the tip of developing blood vessels and polarize to promote lumen formation. Development. 2014;141:4121-6 pubmed publisher
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| De Rossi G, Evans A, Kay E, Woodfin A, McKay T, Nourshargh S, et al. Shed syndecan-2 inhibits angiogenesis. J Cell Sci. 2014;127:4788-99 pubmed publisher
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- immunocytochemistry; human; 1:30
| Lakshminarayan R, Wunder C, Becken U, Howes M, Benzing C, Arumugam S, et al. Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers. Nat Cell Biol. 2014;16:595-606 pubmed publisher
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- western blot; rat
- immunohistochemistry - frozen section; mouse
- immunoprecipitation; mouse
- western blot; mouse
| Wakatsuki S, Araki T, Sehara Fujisawa A. Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing ?5 ?1 integrin-ErbB2-focal adhesion kinase complex formation. Genes Cells. 2014;19:66-77 pubmed publisher
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- immunocytochemistry; mouse; fig 8
| Zhong J, Baquiran J, Bonakdar N, Lees J, Ching Y, Pugacheva E, et al. NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS ONE. 2012;7:e35058 pubmed publisher
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| Chen H, Vandorpe D, Xie X, Alper S, Zeidel M, Yu W. Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology. Nat Commun. 2020;11:4328 pubmed publisher
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| Donnelly S, Cabrera R, Mao S, Christin J, Wu B, Guo W, et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol. 2017;216:4331-4349 pubmed publisher
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| Barbazán J, Alonso Alconada L, Elkhatib N, Geraldo S, Gurchenkov V, Glentis A, et al. Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits. Cancer Res. 2017;77:3431-3441 pubmed publisher
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| Di Russo J, Luik A, Yousif L, Budny S, Oberleithner H, Hofschröer V, et al. Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J. 2017;36:183-201 pubmed publisher
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| Broders Bondon F, Paul Gilloteaux P, Gazquez E, Heysch J, Piel M, Mayor R, et al. Control of the collective migration of enteric neural crest cells by the Complement anaphylatoxin C3a and N-cadherin. Dev Biol. 2016;414:85-99 pubmed publisher
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| Kaanta A, Virtanen C, Selfors L, Brugge J, Neel B. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Res. 2013;15:R65 pubmed
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| Wang Y, Juan H, Wong Y, Kuo W, Lu Y, Lin S, et al. Protogenin prevents premature apoptosis of rostral cephalic neural crest cells by activating the ?5?1-integrin. Cell Death Dis. 2013;4:e651 pubmed publisher
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| Chaen T, Konno T, Egashira M, Bai R, Nomura N, Nomura S, et al. Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS ONE. 2012;7:e48933 pubmed publisher
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| Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, et al. The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res. 2012;22:1479-501 pubmed publisher
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| Petrich B, Marchese P, Ruggeri Z, Spiess S, Weichert R, Ye F, et al. Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007;204:3103-11 pubmed
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| Brockbank E, Bridges J, Marshall C, Sahai E. Integrin beta1 is required for the invasive behaviour but not proliferation of squamous cell carcinoma cells in vivo. Br J Cancer. 2005;92:102-12 pubmed
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| Wang W, Kuo J, Yao C, Chen R. DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals. J Cell Biol. 2002;159:169-79 pubmed
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