product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD14
catalog :
550376
quantity :
1 mL
price :
170.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M5E2
reactivity :
crab eating macaque, African green monkey, human, mouse, dogs, rhesus macaque
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 73
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s6c
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig s5
Di Mascio M, Lifson J, Srinivasula S, Kim I, Degrange P, Keele B, et al. Evaluation of an antibody to α4β7 in the control of SIVmac239-nef-stop infection. Science. 2019;365:1025-1029 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek T, et al. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells. J Immunol. 2018;201:3006-3016 pubmed publisher
  • flow cytometry; human; loading ...; fig s4a
Yeo L, Woodwyk A, Sood S, Lorenc A, Eichmann M, Pujol Autonell I, et al. Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes. J Clin Invest. 2018;128:3460-3474 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Oei V, Siernicka M, Graczyk Jarzynka A, Hoel H, Yang W, Palacios D, et al. Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors. Cancer Immunol Res. 2018;6:467-480 pubmed publisher
  • flow cytometry; human; loading ...; fig 5c
Resheq Y, Menzner A, Bosch J, Tickle J, Li K, Wilhelm A, et al. Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13. J Immunol. 2017;199:1672-1681 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig s16b
Dowling D, van Haren S, Scheid A, Bergelson I, Kim D, Mancuso C, et al. TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth. JCI Insight. 2017;2:e91020 pubmed publisher
  • flow cytometry; human; fig 1a
Cardinaud S, Urrutia A, Rouers A, Coulon P, Kervevan J, Richetta C, et al. Triggering of TLR-3, -4, NOD2, and DC-SIGN reduces viral replication and increases T-cell activation capacity of HIV-infected human dendritic cells. Eur J Immunol. 2017;47:818-829 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Lerner T, Borel S, Greenwood D, Repnik U, Russell M, Herbst S, et al. Mycobacterium tuberculosis replicates within necrotic human macrophages. J Cell Biol. 2017;216:583-594 pubmed publisher
  • blocking or activating experiments; human; loading ...
Horvatinovich J, Grogan E, Norris M, Steinkasserer A, Lemos H, Mellor A, et al. Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes. J Immunol. 2017;198:2286-2301 pubmed publisher
  • flow cytometry; human; loading ...; fig 5
O CONNOR D, Clutterbuck E, Thompson A, Snape M, Ramasamy M, Kelly D, et al. High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine. Genome Med. 2017;9:11 pubmed publisher
  • flow cytometry; human; loading ...
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  • flow cytometry; crab eating macaque; loading ...; fig 3a
Wonderlich E, Swan Z, Bissel S, Hartman A, Carney J, O Malley K, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. J Immunol. 2017;198:1616-1626 pubmed publisher
  • flow cytometry; human; loading ...; fig 1d
Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population. J Immunol. 2016;197:4613-4625 pubmed
  • flow cytometry; human; loading ...
Wang Y, Ma C, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, et al. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016;213:2413-2435 pubmed
  • flow cytometry; human; 1:100; fig 1a
Beatson R, Tajadura Ortega V, Achkova D, Picco G, Tsourouktsoglou T, Klausing S, et al. The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9. Nat Immunol. 2016;17:1273-1281 pubmed publisher
  • flow cytometry; human
Watson D, Bayık D, Srivatsan A, Bergamaschi C, Valentin A, Niu G, et al. Efficient production and enhanced tumor delivery of engineered extracellular vesicles. Biomaterials. 2016;105:195-205 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Cerny D, Thi Le D, The T, Zuest R, Kg S, Velumani S, et al. Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence. J Allergy Clin Immunol. 2016;138:1709-1712.e11 pubmed publisher
  • flow cytometry; human; fig 2a
Di Liberto D, Mansueto P, D Alcamo A, Lo Pizzo M, Lo Presti E, Geraci G, et al. Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet. Clin Transl Gastroenterol. 2016;7:e178 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Piepenbrink M, Samuel M, Zheng B, Carter B, Fucile C, Bunce C, et al. Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users. PLoS ONE. 2016;11:e0158641 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Ebert L, Tan L, Johan M, Min K, Cockshell M, Parham K, et al. A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis. Angiogenesis. 2016;19:463-86 pubmed publisher
  • flow cytometry; human
Pinkenburg O, Meyer T, Bannert N, Norley S, Bolte K, Czudai Matwich V, et al. The Human Antimicrobial Protein Bactericidal/Permeability-Increasing Protein (BPI) Inhibits the Infectivity of Influenza A Virus. PLoS ONE. 2016;11:e0156929 pubmed publisher
  • flow cytometry; African green monkey; loading ...; fig 2a
Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher
  • flow cytometry; human; loading ...; fig s3b
Gren S, Janciauskiene S, Sandeep S, Jonigk D, Kvist P, Gerwien J, et al. The protease inhibitor cystatin C down-regulates the release of IL-? and TNF-? in lipopolysaccharide activated monocytes. J Leukoc Biol. 2016;100:811-822 pubmed
  • flow cytometry; human; 1:200; fig 1
Hollmen M, Karaman S, Schwager S, Lisibach A, Christiansen A, Maksimow M, et al. G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer. Oncoimmunology. 2016;5:e1115177 pubmed
  • flow cytometry; rhesus macaque
Najera J, Bustamante E, Bortell N, Morsey B, Fox H, Ravasi T, et al. Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets. BMC Immunol. 2016;17:7 pubmed publisher
  • flow cytometry; human; fig 1
Yadav A, Betts M, Collman R. Statin modulation of monocyte phenotype and function: implications for HIV-1-associated neurocognitive disorders. J Neurovirol. 2016;22:584-596 pubmed
  • flow cytometry; human; fig 6
Chan Y, Gack M. A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity. Nat Immunol. 2016;17:523-30 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Coughlan A, Harmon C, Whelan S, O Brien E, O Reilly V, Crotty P, et al. Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain. Stem Cells Dev. 2016;25:530-41 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Hülsmann J, Aubin H, Wehrmann A, Jenke A, Lichtenberg A, Akhyari P. Whole-Heart Construct Cultivation Under 3D Mechanical Stimulation of the Left Ventricle. Methods Mol Biol. 2016;1502:181-94 pubmed publisher
  • flow cytometry; human; fig 6
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed publisher
  • flow cytometry; human; loading ...; fig s1f
Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher
  • flow cytometry; human; loading ...; fig 5b
Saliba J, Saint Martin C, Di Stefano A, Lenglet G, Marty C, Keren B, et al. Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. Nat Genet. 2015;47:1131-40 pubmed publisher
  • flow cytometry; human; fig 1e
Jobin C, Cloutier M, Simard C, Néron S. Heterogeneity of in vitro-cultured CD34+ cells isolated from peripheral blood. Cytotherapy. 2015;17:1472-84 pubmed publisher
  • flow cytometry; human; fig S1
Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, et al. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes. J Neuroinflammation. 2015;12:119 pubmed publisher
  • flow cytometry; human
Berent Maoz B, Montecino Rodriguez E, Fice M, Casero D, Seet C, Crooks G, et al. The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS ONE. 2015;10:e0125414 pubmed publisher
  • flow cytometry; African green monkey
Metcalf Pate K, Pohlmeyer C, Walker Sperling V, Foote J, Najarro K, Cryer C, et al. A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads. J Infect Dis. 2015;212:1387-96 pubmed publisher
  • flow cytometry; human; 2.5:100; fig 2a
Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
  • flow cytometry; human; fig 1e
Ohnuma K, Hatano R, Aune T, Otsuka H, Iwata S, Dang N, et al. Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes. J Immunol. 2015;194:3697-712 pubmed publisher
  • flow cytometry; human; fig 1
Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson M, Kekäläinen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
  • flow cytometry; human
Johnson P, Challis R, Chowdhury F, Gao Y, Harvey M, Geldart T, et al. Clinical and biological effects of an agonist anti-CD40 antibody: a Cancer Research UK phase I study. Clin Cancer Res. 2015;21:1321-8 pubmed publisher
  • flow cytometry; human
Hagberg N, Theorell J, Hjorton K, Spee P, Eloranta M, Bryceson Y, et al. Functional anti-CD94/NKG2A and anti-CD94/NKG2C autoantibodies in patients with systemic lupus erythematosus. Arthritis Rheumatol. 2015;67:1000-11 pubmed publisher
  • flow cytometry; rhesus macaque
Campbell J, Ratai E, Autissier P, Nolan D, Tse S, Miller A, et al. Anti-?4 antibody treatment blocks virus traffic to the brain and gut early, and stabilizes CNS injury late in infection. PLoS Pathog. 2014;10:e1004533 pubmed publisher
  • flow cytometry; human
Weihrauch M, Richly H, von Bergwelt Baildon M, Becker H, Schmidt M, Hacker U, et al. Phase I clinical study of the toll-like receptor 9 agonist MGN1703 in patients with metastatic solid tumours. Eur J Cancer. 2015;51:146-56 pubmed publisher
  • flow cytometry; human; fig 1
Williams D, Anastos K, Morgello S, Berman J. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals. J Leukoc Biol. 2015;97:401-12 pubmed publisher
  • flow cytometry; human
Boltjes A, van Montfoort N, Biesta P, Op den Brouw M, Kwekkeboom J, van der Laan L, et al. Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function. J Infect Dis. 2015;211:1268-78 pubmed publisher
  • flow cytometry; human; fig 4
Llosa N, Cruise M, Tam A, Wicks E, Hechenbleikner E, Taube J, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discov. 2015;5:43-51 pubmed publisher
  • flow cytometry; human
Jansen D, Hameetman M, van Bergen J, Huizinga T, van der Heijde D, Toes R, et al. IL-17-producing CD4+ T cells are increased in early, active axial spondyloarthritis including patients without imaging abnormalities. Rheumatology (Oxford). 2015;54:728-35 pubmed publisher
  • immunocytochemistry; mouse
Yu J, Zuo Z, Zhang W, Yang Q, Zhang Y, Tang Y, et al. Identification of immunophenotypic subtypes with different prognoses in extranodal natural killer/T-cell lymphoma, nasal type. Hum Pathol. 2014;45:2255-62 pubmed publisher
  • flow cytometry; human
Hu H, Eller M, Zafar S, Zhou Y, Gu M, Wei Z, et al. Preferential infection of human Ad5-specific CD4 T cells by HIV in Ad5 naturally exposed and recombinant Ad5-HIV vaccinated individuals. Proc Natl Acad Sci U S A. 2014;111:13439-44 pubmed publisher
  • flow cytometry; human
Chao Y, Kaliaperumal N, Chretien A, Tang S, Lee B, Poidinger M, et al. Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα. J Leukoc Biol. 2014;96:1037-46 pubmed publisher
  • flow cytometry; human
Davey M, Morgan M, Liuzzi A, Tyler C, Khan M, Szakmany T, et al. Microbe-specific unconventional T cells induce human neutrophil differentiation into antigen cross-presenting cells. J Immunol. 2014;193:3704-3716 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Kansy B, Dißmann P, Hemeda H, Bruderek K, Westerkamp A, Jagalski V, et al. The bidirectional tumor--mesenchymal stromal cell interaction promotes the progression of head and neck cancer. Stem Cell Res Ther. 2014;5:95 pubmed publisher
  • flow cytometry; human; fig s1
Arlehamn C, Seumois G, Gerasimova A, Huang C, Fu Z, Yue X, et al. Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features. J Immunol. 2014;193:2931-40 pubmed publisher
  • flow cytometry; human
Buggert M, Tauriainen J, Yamamoto T, Frederiksen J, Ivarsson M, Michaelsson J, et al. T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection. PLoS Pathog. 2014;10:e1004251 pubmed publisher
  • immunocytochemistry; human
Campion S, Brodie T, Fischer W, Korber B, Rossetti A, Goonetilleke N, et al. Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors. J Exp Med. 2014;211:1273-80 pubmed publisher
  • flow cytometry; human; loading ...; fig 3d
Kleppa E, Ramsuran V, Zulu S, Karlsen G, Bere A, Passmore J, et al. Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract. PLoS ONE. 2014;9:e98593 pubmed publisher
  • flow cytometry; human
Buggert M, Norstr m M, Salemi M, Hecht F, Karlsson A. Functional avidity and IL-2/perforin production is linked to the emergence of mutations within HLA-B*5701-restricted epitopes and HIV-1 disease progression. J Immunol. 2014;192:4685-96 pubmed publisher
  • flow cytometry; human
Shey M, Nemes E, Whatney W, de Kock M, Africa H, Barnard C, et al. Maturation of innate responses to mycobacteria over the first nine months of life. J Immunol. 2014;192:4833-43 pubmed publisher
  • flow cytometry; rhesus macaque
Cartwright E, McGary C, Cervasi B, Micci L, Lawson B, Elliott S, et al. Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections. J Immunol. 2014;192:4666-73 pubmed publisher
  • flow cytometry; human
Itoua Maïga R, Lemieux J, Roy A, Simard C, Néron S. Flow cytometry assessment of in vitro generated CD138+ human plasma cells. Biomed Res Int. 2014;2014:536482 pubmed publisher
  • flow cytometry; African green monkey; loading ...; fig 9
  • flow cytometry; human; loading ...; fig 9
Trist H, Tan P, Wines B, Ramsland P, Orlowski E, Stubbs J, et al. Polymorphisms and interspecies differences of the activating and inhibitory Fc?RII of Macaca nemestrina influence the binding of human IgG subclasses. J Immunol. 2014;192:792-803 pubmed publisher
  • flow cytometry; human
Zouk H, d Hennezel E, Du X, Ounissi Benkalha H, Piccirillo C, Polychronakos C. Functional evaluation of the role of C-type lectin domain family 16A at the chromosome 16p13 locus. Clin Exp Immunol. 2014;175:485-97 pubmed publisher
  • flow cytometry; human; loading ...; fig 2
Krishnan S, Wilson E, Sheikh V, Rupert A, Mendoza D, Yang J, et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis. 2014;209:931-9 pubmed publisher
  • flow cytometry; human; fig 1
Denecke B, Horsch L, Radtke S, Fischer J, Horn P, Giebel B. Human endothelial colony-forming cells expanded with an improved protocol are a useful endothelial cell source for scaffold-based tissue engineering. J Tissue Eng Regen Med. 2015;9:E84-97 pubmed publisher
  • flow cytometry; human
Roubelakis M, Tsaknakis G, Pappa K, Anagnou N, Watt S. Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization. PLoS ONE. 2013;8:e54747 pubmed publisher
Mir R, Tonelli F, Lis P, MacArtney T, Polinski N, Martinez T, et al. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human. Biochem J. 2018;475:1861-1883 pubmed publisher
Pryke K, Abraham J, Sali T, Gall B, Archer I, Liu A, et al. A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses. MBio. 2017;8: pubmed publisher
Kotini A, Chang C, Chow A, Yuan H, Ho T, Wang T, et al. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia. Cell Stem Cell. 2017;20:315-328.e7 pubmed publisher
Cook A, McDonnell A, Lake R, Nowak A. Dexamethasone co-medication in cancer patients undergoing chemotherapy causes substantial immunomodulatory effects with implications for chemo-immunotherapy strategies. Oncoimmunology. 2016;5:e1066062 pubmed
Bzymek R, Horsthemke M, Isfort K, Mohr S, Tjaden K, Muller Tidow C, et al. Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho. Sci Rep. 2016;6:25016 pubmed publisher
Tsai H, Deng W, Lai W, Chiu W, Yang C, Tsai Y, et al. Wnts enhance neurotrophin-induced neuronal differentiation in adult bone-marrow-derived mesenchymal stem cells via canonical and noncanonical signaling pathways. PLoS ONE. 2014;9:e104937 pubmed publisher
Chen X, Laur O, Kambayashi T, Li S, Bray R, Weber D, et al. Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development. J Exp Med. 2002;195:1053-62 pubmed
product information
Cat.# :
550376
Brand :
BD Pharmingen
Name :
CD14
Format :
Purified
Clone :
M5E2
Isotype :
Ms IgG 2a
React :
Hu , Rhe , Cyno , Dog
Conc :
250 µg/ml
Apps :
FCM , IHC(Fr) , IHC(Zn
Size :
1 mL
Status :
RUO
List Price :
170.00 USD
more info or order :
company information