product summary
company name :
BD Biosciences
other brands :
Transduction Laboratories, PharMingen, Difco
product type :
antibody
product name :
CD45
catalog :
339192
quantity :
100 Tests
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2D1
reactivity :
human, mouse, rhesus macaque
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 49
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 7
Hibl B, Dailey Garnes N, Kneubehl A, Vogt M, Spencer Clinton J, Rico Hesse R. Mosquito-bite infection of humanized mice with chikungunya virus produces systemic disease with long-term effects. PLoS Negl Trop Dis. 2021;15:e0009427 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Crescitelli R, Lässer C, Jang S, Cvjetkovic A, Malmhäll C, Karimi N, et al. Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation. J Extracell Vesicles. 2020;9:1722433 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 2d
Wang H, Shen L, Sun X, Liu F, Feng W, Jiang C, et al. Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity. Nat Commun. 2019;10:3254 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Ruiz Gutierrez M, Bölükbaşı Ö, Alexe G, Kotini A, Ballotti K, Joyce C, et al. Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells. JCI Insight. 2019;5: pubmed publisher
  • flow cytometry; human; loading ...; fig 2b
Fry T, Shah N, Orentas R, Stetler Stevenson M, Yuan C, Ramakrishna S, et al. CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy. Nat Med. 2018;24:20-28 pubmed publisher
  • flow cytometry; human; fig 1a
Mitterreiter J, Ouwendijk W, van Velzen M, van Nierop G, Osterhaus A, Verjans G. Satellite glial cells in human trigeminal ganglia have a broad expression of functional Toll-like receptors. Eur J Immunol. 2017;47:1181-1187 pubmed publisher
  • flow cytometry; human; fig 3d
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, et al. Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities. Oncoimmunology. 2017;6:e1283460 pubmed publisher
  • flow cytometry; human; fig 2b
Millrud C, Kågedal A, Kumlien Georén S, Winqvist O, Uddman R, Razavi R, et al. NET-producing CD16high CD62Ldim neutrophils migrate to tumor sites and predict improved survival in patients with HNSCC. Int J Cancer. 2017;140:2557-2567 pubmed publisher
  • flow cytometry; human; fig s1a
Vernot J, Bonilla X, Rodriguez Pardo V, Vanegas N. Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment. Int J Mol Sci. 2017;18: pubmed publisher
  • flow cytometry; human; loading ...
Salvatori G, Foligno S, Sirleto P, Genovese S, Russo S, Coletti V, et al. Sometimes it is better to wait: First Italian case of a newborn with transient abnormal myelopoiesis and a favorable prognosis. Oncol Lett. 2017;13:191-195 pubmed publisher
  • flow cytometry; human; loading ...; fig s1a
Vanegas N, Vernot J. Loss of quiescence and self-renewal capacity of hematopoietic stem cell in an in vitro leukemic niche. Exp Hematol Oncol. 2017;6:2 pubmed publisher
  • flow cytometry; human; loading ...; fig s1
Bolzoni M, Ronchetti D, Storti P, Donofrio G, Marchica V, Costa F, et al. IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts. Haematologica. 2017;102:773-784 pubmed publisher
  • flow cytometry; human; tbl 3
Fromm J, Thomas A, Wood B. Characterization and Purification of Neoplastic Cells of Nodular Lymphocyte Predominant Hodgkin Lymphoma from Lymph Nodes by Flow Cytometry and Flow Cytometric Cell Sorting. Am J Pathol. 2017;187:304-317 pubmed publisher
  • flow cytometry; human; loading ...
Leibacher J, Dauber K, Ehser S, Brixner V, Kollar K, Vogel A, et al. Human mesenchymal stromal cells undergo apoptosis and fragmentation after intravenous application in immune-competent mice. Cytotherapy. 2017;19:61-74 pubmed publisher
  • flow cytometry; human; fig s4a
Paquin Proulx D, Gibbs A, Bachle S, Checa A, Introini A, Leeansyah E, et al. Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion. J Immunol. 2016;197:1843-51 pubmed publisher
  • flow cytometry; human; fig 1
Seifert A, Zeng S, Zhang J, Kim T, Cohen N, Beckman M, et al. PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors. Clin Cancer Res. 2017;23:454-465 pubmed publisher
  • flow cytometry; human; loading ...
Ashizawa T, Iizuka A, Nonomura C, Kondou R, Maeda C, Miyata H, et al. Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse. Clin Cancer Res. 2017;23:149-158 pubmed publisher
  • flow cytometry; human; fig 1a
Sadallah S, Schmied L, Eken C, Charoudeh H, Amicarella F, Schifferli J. Platelet-Derived Ectosomes Reduce NK Cell Function. J Immunol. 2016;197:1663-71 pubmed publisher
  • flow cytometry; human; fig 1d
Di Liberto D, Mansueto P, D Alcamo A, Lo Pizzo M, Lo Presti E, Geraci G, et al. Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet. Clin Transl Gastroenterol. 2016;7:e178 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Ebert L, Tan L, Johan M, Min K, Cockshell M, Parham K, et al. A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis. Angiogenesis. 2016;19:463-86 pubmed publisher
  • flow cytometry; rhesus macaque; tbl 1
Williams D, Engle E, Shirk E, Queen S, Gama L, Mankowski J, et al. Splenic Damage during SIV Infection: Role of T-Cell Depletion and Macrophage Polarization and Infection. Am J Pathol. 2016;186:2068-2087 pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Marinov I, Illingworth A, Benko M, Sutherland D. Performance Characteristics of a Non-Fluorescent Aerolysin-Based Paroxysmal Nocturnal Hemoglobinuria (PNH) Assay for Simultaneous Evaluation of PNH Neutrophils and PNH Monocytes by Flow Cytometry, Following Published PNH Guidelines. Cytometry B Clin Cytom. 2018;94:257-263 pubmed publisher
  • flow cytometry; human; 1:100; fig 1
Marafini I, Monteleone I, Di Fusco D, Sedda S, Cupi M, Fina D, et al. Celiac Disease-Related Inflammation Is Marked by Reduction of Nkp44/Nkp46-Double Positive Natural Killer Cells. PLoS ONE. 2016;11:e0155103 pubmed publisher
  • flow cytometry; human; loading ...
Carrasco A, Fernández Bañares F, Pedrosa E, Salas A, Loras C, Rosinach M, et al. Regional Specialisation of T Cell Subsets and Apoptosis in the Human Gut Mucosa: Differences Between Ileum and Colon in Healthy Intestine and Inflammatory Bowel Diseases. J Crohns Colitis. 2016;10:1042-54 pubmed publisher
  • flow cytometry; human
Carrasco A, Esteve M, Salas A, Pedrosa E, Rosinach M, Aceituno M, et al. Immunological Differences between Lymphocytic and Collagenous Colitis. J Crohns Colitis. 2016;10:1055-66 pubmed publisher
  • flow cytometry; human
Pilge H, Fröbel J, Mrotzek S, Fischer J, Prodinger P, Zilkens C, et al. Effects of thromboprophylaxis on mesenchymal stromal cells during osteogenic differentiation: an in-vitro study comparing enoxaparin with rivaroxaban. BMC Musculoskelet Disord. 2016;17:108 pubmed publisher
  • flow cytometry; human; fig S1A
Waschbisch A, Schröder S, Schraudner D, Sammet L, Weksler B, Melms A, et al. Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System. J Immunol. 2016;196:1558-67 pubmed publisher
  • flow cytometry; human; fig 8
Kaplan J, Marshall M, C McSkimming C, Harmon D, Garmey J, Oldham S, et al. Adipocyte progenitor cells initiate monocyte chemoattractant protein-1-mediated macrophage accumulation in visceral adipose tissue. Mol Metab. 2015;4:779-94 pubmed publisher
  • flow cytometry; human; loading ...; fig s1e
Schulz A, Mälzer J, Domingo C, Jürchott K, Grützkau A, Babel N, et al. Low Thymic Activity and Dendritic Cell Numbers Are Associated with the Immune Response to Primary Viral Infection in Elderly Humans. J Immunol. 2015;195:4699-711 pubmed publisher
  • flow cytometry; human; tbl 4
Fromm J, Tagliente D, Shaver A, Neppalli V, Craig F. Case study interpretation: Report from the ICCS Annual Meeting, Seattle, 2014. Cytometry B Clin Cytom. 2015;88:413-24 pubmed publisher
  • flow cytometry; human
Yukl S, Shergill A, Girling V, Li Q, Killian M, Epling L, et al. Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults. PLoS ONE. 2015;10:e0121290 pubmed publisher
  • immunohistochemistry; human
Strick Marchand H, Dusséaux M, Darche S, Huntington N, Legrand N, Masse Ranson G, et al. A novel mouse model for stable engraftment of a human immune system and human hepatocytes. PLoS ONE. 2015;10:e0119820 pubmed publisher
  • flow cytometry; human; fig s1
Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, et al. Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens. Immunol Cell Biol. 2015;93:727-34 pubmed publisher
  • flow cytometry; human
Bettman N, Avivi I, Rosenbaum H, Bisharat L, Katz T. Impaired migration capacity in monocytes derived from patients with Gaucher disease. Blood Cells Mol Dis. 2015;55:180-6 pubmed publisher
  • flow cytometry; human
Bigley V, McGovern N, Milne P, Dickinson R, Pagan S, Cookson S, et al. Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cells. J Leukoc Biol. 2015;97:627-34 pubmed publisher
  • flow cytometry; human; fig s1
Boltjes A, van Montfoort N, Biesta P, Op den Brouw M, Kwekkeboom J, van der Laan L, et al. Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function. J Infect Dis. 2015;211:1268-78 pubmed publisher
  • flow cytometry; human; fig 3d
  • flow cytometry; mouse; loading ...; fig 6c
Santoro S, Kim S, Motz G, Alatzoglou D, Li C, Irving M, et al. T cells bearing a chimeric antigen receptor against prostate-specific membrane antigen mediate vascular disruption and result in tumor regression. Cancer Immunol Res. 2015;3:68-84 pubmed publisher
  • flow cytometry; human; fig 4
Llosa N, Cruise M, Tam A, Wicks E, Hechenbleikner E, Taube J, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discov. 2015;5:43-51 pubmed publisher
  • flow cytometry; human; fig 4
Cai X, Dai Z, Reeves R, Caballero Benítez A, Duran K, Delrow J, et al. Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells. PLoS ONE. 2014;9:e108942 pubmed publisher
  • flow cytometry; human; 5 ul per test
Rasmussen S, Bilgrau A, Schmitz A, Falgreen S, Bergkvist K, Tramm A, et al. Stable Phenotype Of B-Cell Subsets Following Cryopreservation and Thawing of Normal Human Lymphocytes Stored in a Tissue Biobank. Cytometry B Clin Cytom. 2014;: pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Frigyesi I, Adolfsson J, Ali M, Christophersen M, Johnsson E, Turesson I, et al. Robust isolation of malignant plasma cells in multiple myeloma. Blood. 2014;123:1336-40 pubmed publisher
  • flow cytometry; human; tbl 1
Stacchini A, Aliberti S, Pacchioni D, Demurtas A, Isolato G, Gazzera C, et al. Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands. Cytopathology. 2014;25:231-40 pubmed publisher
  • flow cytometry; human
Raynaud C, Halabi N, Elliott D, Pasquier J, Elefanty A, Stanley E, et al. Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes. PLoS ONE. 2013;8:e54524 pubmed publisher
Seebach C, Henrich D, Meier S, Nau C, Bonig H, Marzi I. Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans. J Transl Med. 2016;14:314 pubmed
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
Wan X, Guloglu F, Vanmorlan A, Rowland L, Zaghouani S, Cascio J, et al. Recovery from overt type 1 diabetes ensues when immune tolerance and ?-cell formation are coupled with regeneration of endothelial cells in the pancreatic islets. Diabetes. 2013;62:2879-89 pubmed publisher
Touboul C, Lis R, Al Farsi H, Raynaud C, Warfa M, Althawadi H, et al. Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model. J Transl Med. 2013;11:28 pubmed publisher
Raynaud C, Maleki M, Lis R, Ahmed B, Al Azwani I, Malek J, et al. Comprehensive characterization of mesenchymal stem cells from human placenta and fetal membrane and their response to osteoactivin stimulation. Stem Cells Int. 2012;2012:658356 pubmed publisher
Broxmeyer H, Orschell C, Clapp D, Hangoc G, Cooper S, Plett P, et al. Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med. 2005;201:1307-18 pubmed
product information
Cat.# :
339192
Name :
CD45
Format :
AmCyan
Clone :
2D1
Isotype :
Ms IgG 1
React :
Hu
Apps :
FCM
Size :
100 Tests
Status :
RUO (GMP
more info or order :
company information