Mrc1 Antibody (OASA05048) | Aviva Systems Biology oasa05048 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

Mrc1 Antibody (OASA05048)

catalog :

oasa05048

quantity :

25 ug

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

MR5D3

The same clone is also sold as:

Invitrogen: MA5-16870, MA5-16869, MA5-16872, MA5-16868, MA5-16871
MyBioSource: MBS215657
Santa Cruz Biotechnology: sc-58987
Bio-Rad: MCA2235PB, MCA2235B, MCA2235FB, MCA2235T, MCA2235GA, MCA2235FA, MCA2235PET, MCA2235A488, MCA2235FT, MCA2235A647T, MCA2235BT, MCA2235A647, MCA2235A488T, MCA2235P750, MCA2235PE, MCA2235, MCA2235F
OriGene: SM1857B, SM1857P, SM1857F, SM1857R, SM1857LE, SM1857PS

reactivity :

mouse

application :

flow cytometry

citations: 1

Reference
Mareninova O, Sendler M, Malla S, Yakubov I, French S, Tokhtaeva E, et al. Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis. Cell Mol Gastroenterol Hepatol. 2015;1:678-694 pubmed

product information

sku :

OASA05048

product type :

Monoclonal Antibody

category :

Monoclonal

name :

Mrc1 Antibody (OASA05048)

size :

25 ug

gene symbol :

MRC1

alias symbols :

RAT ANTI MOUSE CD206; CD206; MANNOSE RECEPTOR C TYPE 1

protein accession num :

NP_032651.2

swissprot id :

Q61830

species reactivity :

Mouse

product format :

Liquid PBS with 0.09% sodium azide

reconstitution and storage :

Store at 4 C or at -20 C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate, microcentrifuge before use. Shelf Life: 18 months from date of dispatch

description of target :

The mannose receptor, CD26, is composed of a N-terminal cysteine-rich domain, a fibronectin type II domain, eight tandemly arranged C-type lectin domains (CTLD), a transmembrane domain, and a cytoplasmic domain. The terminal cysteine-rich domain binds sulfated sugars, and the CTLD recognizes carbohydrates terminating in mannose, fucose and N-acetylglucosamine, all sugars found on microorganisms and on some endogenous proteins. Rat anti mouse CD26 antibody, clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands. Clone MR5D3 has also been shown to work in Western Blot.

host :

Rat

application :

purification :

Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

clonality :

Monoclonal

clone :

MR5D3

specificity :

Rat anti mouse CD206 antibody, clone MR5D3 recognizes the mouse mannose receptor, a 175 kDa type 1 membrane glycoprotein that is also known as CD206. CD206 is expressed on most tissue macrophages, certain endothelial cells, and in vitro derived dendritic cells.

immunogen :

Chimaeric CRD4-7-Fc protein.

application info :

FC: 1/10-1/20. Use 10 uL of the suggested working dilution to label 106 cells in 100 uL. CD206 is expressed weakly at the cell surface. Staining may be increased following membrane permeabilisation.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use their own system using appropriate negative/positive controls.

drywet surcharge :

Wet Ice

storage temperature :

-20C