Fibrinogen ELISA Kit (Human) (OKIA00063) | Aviva Systems Biology OKIA00063 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

Fibrinogen ELISA Kit (Human) (OKIA00063)

catalog :

OKIA00063

quantity :

96 Wells

product information

sku :

OKIA00063

product type :

Application Kit

category :

ELISA Kits

name :

Fibrinogen ELISA Kit (Human) (OKIA00063)

size :

96 Wells

gene symbol :

FGA

alias symbols :

Fibrinogen alpha chain, FGA

swissprot id :

P02671

species reactivity :

Human

product format :

In Solution

reconstitution and storage :

Store as indicated in product manual.

description of target :

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

application :

ELISA

homology :

Human

assay info :

Assay Methodology: Quantitative Sandwich ELISA

sensitivity :

2.088 ng/ml

drywet surcharge :

Wet Ice

storage temperature :