REN ELISA Kit (Human) : 96 Wells (OKEH00656) | Aviva Systems Biology OKEH00656 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

REN ELISA Kit (Human) : 96 Wells (OKEH00656)

catalog :

OKEH00656

quantity :

96 Wells

product information

sku :

OKEH00656

product type :

Application Kit

category :

ELISA Kits

name :

REN ELISA Kit (Human) : 96 Wells (OKEH00656)

size :

96 Wells

gene symbol :

REN

alias symbols :

Angiotensinogenase, FLJ10761, HNFJ2, Renin

nucleotide accession num :

NM_000537.3

protein accession num :

NP_000528.1

swissprot id :

P00797

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 28]

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

< 3.90 pg/mL

specificity :

This assay recognizes recombinant and natural human Renin. No significant cross-reactivity or interference was observed.

drywet surcharge :

Wet Ice

storage temperature :