DCX ELISA Kit (Mouse) (OKDD00730) | Aviva Systems Biology OKDD00730 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

DCX ELISA Kit (Mouse) (OKDD00730)

catalog :

OKDD00730

quantity :

96 Wells

product information

sku :

OKDD00730

product type :

Application Kit

category :

ELISA Kits

name :

DCX ELISA Kit (Mouse) (OKDD00730)

size :

96 Wells

gene symbol :

DCX

alias symbols :

Dbct

nucleotide accession num :

NM_001110222.1

protein accession num :

NP_001103692.1

swissprot id :

O88809

species reactivity :

Mouse

reconstitution and storage :

Store as indicated in product manual.

description of target :

This gene encodes a member of the doublecortin family. the protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. in the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. the encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. in addition, the encoded protein interacts with lis1, the regulatory gamma subunit of platelet activating factor acetylhydrolase. studies in knockout mice lacking this gene and the lis1 gene suggest that the molecular interaction of these two genes is important in both in neuronal migration and neurogenesis, and there is a cortical role of this gene in nuclear translocation and positioning of the mitotic spindle in radial glial mitotic division. multiple transcript variants encoding three different isoforms have been found for this gene.

assay info :

Quantitative Sandwich ELISA

sensitivity :

<0.051 ng/mL

specificity :

This assay has high sensitivity and excellent specificity for detection of DCX. No significant cross-reactivity or interference between DCX and analogues was observed.

drywet surcharge :

Wet Ice

storage temperature :