PSMa7 ELISA Kit (Human) (OKDD00489) | Aviva Systems Biology OKDD00489 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

PSMa7 ELISA Kit (Human) (OKDD00489)

catalog :

OKDD00489

quantity :

96 Wells

product information

sku :

OKDD00489

product type :

Application Kit

category :

ELISA Kits

name :

PSMa7 ELISA Kit (Human) (OKDD00489)

size :

96 Wells

gene symbol :

PSMa7

alias symbols :

C6, HSPC, MGC3755, Proteasome subunit alpha type-7, Proteasome subunit RC6-1, Proteasome subunit XAPC7, RC6-1, XAPC7

nucleotide accession num :

NM_002792.3

protein accession num :

NP_002783.1

swissprot id :

O14818

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 2S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

assay info :

Quantitative Sandwich ELISA

sensitivity :

< 0.055 ng/mL

specificity :

This assay has high sensitivity and excellent specificity for detection of PSMa7. No significant cross-reactivity or interference between PSMa7 and analogues was observed.

drywet surcharge :

Wet Ice

storage temperature :