DSC1 ELISA Kit (Human) (OKDD00242) | Aviva Systems Biology OKDD00242 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

DSC1 ELISA Kit (Human) (OKDD00242)

catalog :

OKDD00242

quantity :

96 Wells

product information

sku :

OKDD00242

product type :

Application Kit

category :

ELISA Kits

name :

DSC1 ELISA Kit (Human) (OKDD00242)

size :

96 Wells

gene symbol :

DSC1

alias symbols :

Cadherin family member 1, CDHF1, Desmocollin-1, Desmosomal glycoprotein 2/3, DG2/DG3

nucleotide accession num :

NM_004948.3

protein accession num :

NP_004939.1

swissprot id :

Q08554

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.

assay info :

Quantitative Sandwich ELISA

sensitivity :

< 0.057 ng/mL

specificity :

This assay has high sensitivity and excellent specificity for detection of DSC1. No significant cross-reactivity or interference between DSC1 and analogues was observed.

drywet surcharge :

Wet Ice

storage temperature :