ELISA/assay

ATF4 ELISA Kit (Human) (OKDD00138)

OKDD00138

96 Wells

Application Kit

ELISA Kits

ATF4 ELISA Kit (Human) (OKDD00138)

96 Wells

ATF4

Activating transcription factor 4, cAMP-dependent transcription factor ATF-4, cAMP-responsive element-binding protein 2, CREB2, CREB-2, Cyclic AMP-dependent transcription factor ATF-4, Cyclic AMP-responsive element-binding protein 2, DNA-binding protein T

NM_001675.4

NP_001666.2

P18848

Human

Store as indicated in product manual.

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Quantitative Sandwich ELISA

< 0.057 ng/mL

This assay has high sensitivity and excellent specificity for detection of ATF4. No significant cross-reactivity or interference between ATF4 and analogues was observed.

Wet Ice

4C