F8 ELISA Kit (Human) (OKCD07761) | Aviva Systems Biology OKCD07761 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

F8 ELISA Kit (Human) (OKCD07761)

catalog :

OKCD07761

quantity :

96 Wells

product information

sku :

OKCD07761

product type :

Application Kit

category :

ELISA Kits

name :

F8 ELISA Kit (Human) (OKCD07761)

size :

96 Wells

gene symbol :

alias symbols :

FVIII; AHF; HEMA; F8B; F8C; Antihemophilic Globulin; Hemophilia A; Anti-Hemophilic Factor A; FVIII Procoagulant Component; F8 Protein

nucleotide accession num :

NP_000123.1

protein accession num :

NM_000132.3

swissprot id :

P00451

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

application :

ELISA

sensitivity :

< 30pg/mL

drywet surcharge :

Wet Ice

storage temperature :