NOS2 ELISA Kit (Rabbit) (OKCD01548) | Aviva Systems Biology OKCD01548 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

NOS2 ELISA Kit (Rabbit) (OKCD01548)

catalog :

OKCD01548

quantity :

96 Wells

product information

sku :

OKCD01548

product type :

Application Kit

category :

ELISA Kits

name :

NOS2 ELISA Kit (Rabbit) (OKCD01548)

size :

96 Wells

gene symbol :

NOS2

alias symbols :

NOS2, Nitric oxide synthase, inducible, nitric oxide synthase 2, inducible

nucleotide accession num :

XM_017349094.1

protein accession num :

XP_017204583.1

swissprot id :

O19114

species reactivity :

Rabbit

reconstitution and storage :

Store as indicated in product manual.

description of target :

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S1A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

< 0.064 ng/mL

specificity :

This assay has high sensitivity and excellent specificity for detection of Nitric Oxide Synthase 2, Inducible (NOS2). No significant cross-reactivity or interference between Nitric Oxide Synthase 2, Inducible (NOS2) and analogues was observed.

drywet surcharge :

Wet Ice

storage temperature :

2-8C