MMP13 ELISA Kit (Horse) (OKCD01470) | Aviva Systems Biology OKCD01470 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

MMP13 ELISA Kit (Horse) (OKCD01470)

catalog :

OKCD01470

quantity :

96 Wells

product information

sku :

OKCD01470

product type :

Application Kit

category :

ELISA Kits

name :

MMP13 ELISA Kit (Horse) (OKCD01470)

size :

96 Wells

gene symbol :

MMP13

alias symbols :

MMP13, Collagenase 3, matrix metallopeptidase 13 (collagenase 3)

nucleotide accession num :

NM_001081804.1

protein accession num :

NP_001075273.1

swissprot id :

O18927

species reactivity :

Horse

reconstitution and storage :

Store as indicated in product manual.

description of target :

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

< 0.29 ng/mL

specificity :

This assay has high sensitivity and excellent specificity for detection of Matrix Metalloproteinase 13 (MMP13). No significant cross-reactivity or interference between Matrix Metalloproteinase 13 (MMP13) and analogues was observed.

drywet surcharge :

Wet Ice

storage temperature :

2-8C