ARG2 ELISA Kit (Human) (OKCD01118) | Aviva Systems Biology OKCD01118 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

ARG2 ELISA Kit (Human) (OKCD01118)

catalog :

OKCD01118

quantity :

96 Wells

product information

sku :

OKCD01118

product type :

Application Kit

category :

ELISA Kits

name :

ARG2 ELISA Kit (Human) (OKCD01118)

size :

96 Wells

gene symbol :

ARG2

alias symbols :

Arginase-2, mitochondrial, Kidney-type arginase, Non-hepatic arginase, Type II arginase

nucleotide accession num :

NM_009705.3

protein accession num :

NP_033835

swissprot id :

P78540

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.1 Publication p>Manually curated information for which there is published experimental evidence. /p> a href="/manual/evidences#ECO:269">MoreÃ¢â‚¬Â¦ /a> /p> Manual assertion based on experiment iniRef.1"Human arginase II: crystal structure and physiological role in male and female sexual arousal." Cama E., Colleluori D.M., Emig F.A., Shin H., Kim S.W., Kim N.N., Traish A.M., Ash D.E., Christianson D.W. Biochemistry 42:8445-8451(23) [PubMed] [Europe PMC] [Abstract]Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 24-329 IN COMPLEX WITH MANGANESE IONS AND S-2-(BORONOETHYL)-L-CYSTEINE, COFACTOR, SUBUNIT, FUNCTION, CATALYTIC ACTIVITY.

application :

ELISA

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

< 1.17 ng/mL

specificity :

This assay has high sensitivity and excellent specificity for detection of Arginase II (Arg2). No significant cross-reactivity or interference between Arginase II (Arg2) and analogues was observed.

drywet surcharge :

Wet Ice

storage temperature :